- Home
- Publications
- Publication Search
- Publication Details
Title
Gene-Specific Targeting of DNA Methylation in the Mammalian Genome
Authors
Keywords
-
Journal
Cancers
Volume 11, Issue 10, Pages 1515
Publisher
MDPI AG
Online
2019-10-09
DOI
10.3390/cancers11101515
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Reprogrammable CRISPR/dCas9-based recruitment of DNMT1 for site-specific DNA demethylation and gene regulation
- (2019) Anrui Lu et al. Cell Discovery
- Rescue of Fragile X Syndrome Neurons by DNA Methylation Editing of the FMR1 Gene
- (2018) X. Shawn Liu et al. CELL
- A modular dCas9-SunTag DNMT3A epigenome editing system overcomes pervasive off-target activity of direct fusion dCas9-DNMT3A constructs
- (2018) Christian Pflueger et al. GENOME RESEARCH
- The CRISPR tool kit for genome editing and beyond
- (2018) Mazhar Adli Nature Communications
- Targeted DNA demethylation in human cells by fusion of a plant 5-methylcytosine DNA glycosylase to a sequence-specific DNA binding domain
- (2017) Jara Teresa Parrilla-Doblas et al. Epigenetics
- Epigenetic drivers of tumourigenesis and cancer metastasis
- (2017) Aniruddha Chatterjee et al. SEMINARS IN CANCER BIOLOGY
- Stabilization of Foxp3 expression by CRISPR-dCas9-based epigenome editing in mouse primary T cells
- (2017) Masahiro Okada et al. Epigenetics & Chromatin
- Hit-and-run epigenetic editing prevents senescence entry in primary breast cells from healthy donors
- (2017) Emily A. Saunderson et al. Nature Communications
- Targeted DNA methylation in vivo using an engineered dCas9-MQ1 fusion protein
- (2017) Yong Lei et al. Nature Communications
- DNA hypermethylation enhanced telomerase reverse transcriptase expression in human-induced pluripotent stem cells
- (2017) Ken Takasawa et al. Human Cell
- Targeted DNA methylation in human cells using engineered dCas9-methyltransferases
- (2017) Tina Xiong et al. Scientific Reports
- Inhibiting DNA Methylation Causes an Interferon Response in Cancer via dsRNA Including Endogenous Retroviruses
- (2016) Katherine B. Chiappinelli et al. CELL
- Inheritable Silencing of Endogenous Genes by Hit-and-Run Targeted Epigenetic Editing
- (2016) Angelo Amabile et al. CELL
- Editing DNA Methylation in the Mammalian Genome
- (2016) X. Shawn Liu et al. CELL
- Tumour hypoxia causes DNA hypermethylation by reducing TET activity
- (2016) Bernard Thienpont et al. NATURE
- Targeted DNA demethylation in vivo using dCas9–peptide repeat and scFv–TET1 catalytic domain fusions
- (2016) Sumiyo Morita et al. NATURE BIOTECHNOLOGY
- A dual AAV system enables the Cas9-mediated correction of a metabolic liver disease in newborn mice
- (2016) Yang Yang et al. NATURE BIOTECHNOLOGY
- Epigenetic Modulators and the New Immunotherapies
- (2016) Anthony E. Dear NEW ENGLAND JOURNAL OF MEDICINE
- Efficient targeted DNA methylation with chimeric dCas9–Dnmt3a–Dnmt3L methyltransferase
- (2016) Peter Stepper et al. NUCLEIC ACIDS RESEARCH
- Repurposing the CRISPR-Cas9 system for targeted DNA methylation
- (2016) Aleksandar Vojta et al. NUCLEIC ACIDS RESEARCH
- scan_tcga tools for integrated epigenomic and transcriptomic analysis of tumor subgroups
- (2016) Aniruddha Chatterjee et al. Epigenomics
- Genome-wide methylation sequencing of paired primary and metastatic cell lines identifies common DNA methylation changes and a role for EBF3 as a candidate epigenetic driver of melanoma metastasis
- (2016) Aniruddha Chatterjee et al. Oncotarget
- CRISPR-dCas9 mediated TET1 targeting for selective DNA demethylation at BRCA1 promoter
- (2016) Samrat Roy Choudhury et al. Oncotarget
- Placental Hypomethylation Is More Pronounced in Genomic Loci Devoid of Retroelements
- (2016) Aniruddha Chatterjee et al. G3-Genes Genomes Genetics
- Reprogrammable CRISPR/Cas9-based system for inducing site-specific DNA methylation
- (2016) James I. McDonald et al. Biology Open
- A CRISPR-based approach for targeted DNA demethylation
- (2016) Xingxing Xu et al. Cell Discovery
- DNA-Demethylating Agents Target Colorectal Cancer Cells by Inducing Viral Mimicry by Endogenous Transcripts
- (2015) David Roulois et al. CELL
- Molecular Pathways: At the Crossroads of Cancer Epigenetics and Immunotherapy
- (2015) M. Maio et al. CLINICAL CANCER RESEARCH
- Genome-wide specificity of DNA binding, gene regulation, and chromatin remodeling by TALE- and CRISPR/Cas9-based transcriptional activators
- (2015) Lauren R. Polstein et al. GENOME RESEARCH
- Epigenetic silencing of TH1-type chemokines shapes tumour immunity and immunotherapy
- (2015) Dongjun Peng et al. NATURE
- Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers
- (2015) Isaac B Hilton et al. NATURE BIOTECHNOLOGY
- Epigenetic activation of a cryptic TBC1D16 transcript enhances melanoma progression by targeting EGFR
- (2015) Miguel Vizoso et al. NATURE MEDICINE
- Highly specific epigenome editing by CRISPR-Cas9 repressors for silencing of distal regulatory elements
- (2015) Pratiksha I Thakore et al. NATURE METHODS
- A genome-wide analysis of Cas9 binding specificity using ChIP-seq and targeted sequence capture
- (2015) Henriette O'Geen et al. NUCLEIC ACIDS RESEARCH
- In vivo gene editing in dystrophic mouse muscle and muscle stem cells
- (2015) M. Tabebordbar et al. SCIENCE
- In vivo genome editing improves muscle function in a mouse model of Duchenne muscular dystrophy
- (2015) C. E. Nelson et al. SCIENCE
- DNA methylation and epigenomics: new technologies and emerging concepts
- (2015) Aniruddha Chatterjee et al. GENOME BIOLOGY
- Alterations of immune response of non-small cell lung cancer with Azacytidine
- (2015) John Wrangle et al. Oncotarget
- A Protein-Tagging System for Signal Amplification in Gene Expression and Fluorescence Imaging
- (2014) Marvin E. Tanenbaum et al. CELL
- Genome-wide identification of CRISPR/Cas9 off-targets in human genome
- (2014) Jinzhi Duan et al. CELL RESEARCH
- DNA demethylation, Tet proteins and 5-hydroxymethylcytosine in epigenetic reprogramming: An emerging complex story
- (2014) Peter W.S. Hill et al. GENOMICS
- Hypermethylation of the alternative AWT1 promoter in hematological malignancies is a highly specific marker for acute myeloid leukemias despite high expression levels
- (2014) Amy Guillaumet-Adkins et al. Journal of Hematology & Oncology
- Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells
- (2014) Xuebing Wu et al. NATURE BIOTECHNOLOGY
- In vivo interrogation of gene function in the mammalian brain using CRISPR-Cas9
- (2014) Lukasz Swiech et al. NATURE BIOTECHNOLOGY
- Cationic lipid-mediated delivery of proteins enables efficient protein-based genome editing in vitro and in vivo
- (2014) John A Zuris et al. NATURE BIOTECHNOLOGY
- A Comprehensive View of the Epigenetic Landscape Part I: DNA Methylation, Passive and Active DNA Demethylation Pathways and Histone Variants
- (2014) Anna Sadakierska-Chudy et al. NEUROTOXICITY RESEARCH
- Analysis of an artificial zinc finger epigenetic modulator: widespread binding but limited regulation
- (2014) Matthew R. Grimmer et al. NUCLEIC ACIDS RESEARCH
- The new frontier of genome engineering with CRISPR-Cas9
- (2014) J. A. Doudna et al. SCIENCE
- 5-hydroxymethylcytosine: a potential therapeutic target in cancer
- (2014) Euan J Rodger et al. Epigenomics
- Cancer statistics, 2013
- (2013) Rebecca Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- CRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes
- (2013) Luke A. Gilbert et al. CELL
- Specific transcriptional enhancement of inducible nitric oxide synthase by targeted promoter demethylation
- (2013) David J Gregory et al. Epigenetics
- Basic concepts of epigenetics
- (2013) Michal Inbar-Feigenberg et al. FERTILITY AND STERILITY
- Cancer Development, Progression, and Therapy: An Epigenetic Overview
- (2013) Sibaji Sarkar et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Methylation of the TERT promoter and risk stratification of childhood brain tumours: an integrative genomic and molecular study
- (2013) Pedro Castelo-Branco et al. LANCET ONCOLOGY
- Charting a dynamic DNA methylation landscape of the human genome
- (2013) Michael J. Ziller et al. NATURE
- Targeted DNA demethylation and activation of endogenous genes using programmable TALE-TET1 fusion proteins
- (2013) Morgan L Maeder et al. NATURE BIOTECHNOLOGY
- RNA-guided gene activation by CRISPR-Cas9–based transcription factors
- (2013) Pablo Perez-Pinera et al. NATURE METHODS
- Genome engineering using the CRISPR-Cas9 system
- (2013) F Ann Ran et al. Nature Protocols
- The future of epigenetic therapy in solid tumours—lessons from the past
- (2013) Nilofer Azad et al. Nature Reviews Clinical Oncology
- DNA methylation: roles in mammalian development
- (2013) Zachary D. Smith et al. NATURE REVIEWS GENETICS
- Induced DNA demethylation by targeting Ten-Eleven Translocation 2 to the human ICAM-1 promoter
- (2013) Hui Chen et al. NUCLEIC ACIDS RESEARCH
- Cancer Genome Landscapes
- (2013) B. Vogelstein et al. SCIENCE
- AID/APOBEC deaminases disfavor modified cytosines implicated in DNA demethylation
- (2012) Christopher S Nabel et al. Nature Chemical Biology
- Epigenetic mechanisms in neurological disease
- (2012) Mira Jakovcevski et al. NATURE MEDICINE
- Functions of DNA methylation: islands, start sites, gene bodies and beyond
- (2012) Peter A. Jones NATURE REVIEWS GENETICS
- TALENs: a widely applicable technology for targeted genome editing
- (2012) J. Keith Joung et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- DNA Methylation and Its Basic Function
- (2012) Lisa D Moore et al. NEUROPSYCHOPHARMACOLOGY
- A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity
- (2012) M. Jinek et al. SCIENCE
- Expression of the TIMP2 gene is not regulated by promoter hypermethylation in the Caski cell line
- (2012) GAURAV PARASHAR et al. Oncology Letters
- Thymine DNA Glycosylase Is Essential for Active DNA Demethylation by Linked Deamination-Base Excision Repair
- (2011) Salvatore Cortellino et al. CELL
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- Epigenetic Control of Angiogenesis via DNA Methylation
- (2011) Marcus P. Cooper et al. CIRCULATION
- Cancer epigenetics reaches mainstream oncology
- (2011) Manuel Rodríguez-Paredes et al. NATURE MEDICINE
- hTERT promoter activity and CpG methylation in HPV-induced carcinogenesis
- (2010) Jillian de Wilde et al. BMC CANCER
- Targeting DNA Double-Strand Breaks with TAL Effector Nucleases
- (2010) M. Christian et al. GENETICS
- Direct detection of DNA methylation during single-molecule, real-time sequencing
- (2010) Benjamin A Flusberg et al. NATURE METHODS
- Genome editing with engineered zinc finger nucleases
- (2010) Fyodor D. Urnov et al. NATURE REVIEWS GENETICS
- Tumor-associated CpG demethylation augments hypoxia-induced effects by positive autoregulation of HIF-1α
- (2010) M Koslowski et al. ONCOGENE
- Epigenetics in cancer
- (2009) S. Sharma et al. CARCINOGENESIS
- Targeting DNA Methylation
- (2009) J.-P. J. Issa et al. CLINICAL CANCER RESEARCH
- Efficacy of azacitidine compared with that of conventional care regimens in the treatment of higher-risk myelodysplastic syndromes: a randomised, open-label, phase III study
- (2009) Pierre Fenaux et al. LANCET ONCOLOGY
- Coordinated Activation of Candidate Proto-Oncogenes and Cancer Testes Antigens via Promoter Demethylation in Head and Neck Cancer and Lung Cancer
- (2009) Ian M. Smith et al. PLoS One
- Epigenetics in Cancer
- (2008) Manel Esteller NEW ENGLAND JOURNAL OF MEDICINE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now