Impact of Oxidative Stress on Age-Associated Decline in Oocyte Developmental Competence

Melatonin regulates the activities of ovary and delays the fertility decline in female animals via MT1/AMPK pathway

(2019) Lu Zhang et al.   JOURNAL OF PINEAL RESEARCH

Direct Single-Cell Analysis of Human Polar Bodies and Cleavage-Stage Embryos Reveals No Evidence of the Telomere Theory of Reproductive Ageing in Relation to Aneuploidy Generation

(2019) Kara Turner et al.   Cells

SIRT6 participates in the quality control of aged oocytes via modulating telomere function

(2019) Juan Ge et al.   Aging-US

Mitofusin 2 plays a role in oocyte and follicle development, and is required to maintain ovarian follicular reserve during reproductive aging

(2019) Man Zhang et al.   Aging-US

Longitudinal analysis of somatic and germ-cell telomere dynamics in outbred mice

(2019) Priscila Ramos-Ibeas et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT

Mitofusin 1 is required for female fertility and to maintain ovarian follicular reserve

(2019) Man Zhang et al.   Cell Death & Disease

A Biochemical Approach to Detect Oxidative Stress in Infertile Women Undergoing Assisted Reproductive Technology Procedures

(2018) Matteo Becatti et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Clonal expansion of mitochondrial DNA deletions is a private mechanism of aging in long-lived animals

(2018) Lakshmi Narayanan Lakshmanan et al.   AGING CELL

Oxidative Stress Mediates Microcystin-LR-Induced Endoplasmic Reticulum Stress and Autophagy in KK-1 Cells and C57BL/6 Mice Ovaries

(2018) Haohao Liu et al.   Frontiers in Physiology

Alterations in oocyte mitochondrial number and function are related to spindle defects and occur with maternal aging in mice and humans†

(2018) Rolando Pasquariello et al.   BIOLOGY OF REPRODUCTION

Lycium barbarum polysaccharide improves the development of mouse oocytes vitrified at the germinal vesicle stage

(2018) Lei Yang et al.   CRYOBIOLOGY

Oxidative damage in naturally aged mouse oocytes is exacerbated by dysregulation of proteasomal activity

(2018) Bettina P. Mihalas et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Intrinsic fertility of human oocytes

(2017) Sherman J. Silber et al.   FERTILITY AND STERILITY

Clinical implications of mitochondrial DNA quantification on pregnancy outcomes: a blinded prospective non-selection study

(2017) Elpida Fragouli et al.   HUMAN REPRODUCTION

Long-term melatonin treatment delays ovarian aging

(2017) Hiroshi Tamura et al.   JOURNAL OF PINEAL RESEARCH

Intracytoplasmic oxidative stress reverses epigenetic modifications in polycystic ovary syndrome

(2017) Fatemeh Eini et al.   REPRODUCTION FERTILITY AND DEVELOPMENT

c-Abl-mediated Drp1 phosphorylation promotes oxidative stress-induced mitochondrial fragmentation and neuronal cell death

(2017) Lujun Zhou et al.   Cell Death & Disease

Mitochondrial DNA 4977 bp deletion is a common phenomenon in hair and increases with age

(2017) Yijie Zheng et al.   Bosnian Journal of Basic Medical Sciences

The lipid peroxidation product 4-hydroxynonenal contributes to oxidative stress-mediated deterioration of the ageing oocyte

(2017) Bettina P. Mihalas et al.   Scientific Reports

SIRT6, oxidative stress and aging

(2016) Chen-Yu Liao et al.   CELL RESEARCH

Role ofSirt3in mitochondrial biogenesis and developmental competence of humanin vitromatured oocytes

(2016) Hong-Cui Zhao et al.   HUMAN REPRODUCTION

Ovarian ageing: the role of mitochondria in oocytes and follicles

(2016) Pascale May-Panloup et al.   HUMAN REPRODUCTION UPDATE

Oxidative stress in oocytes during midprophase induces premature loss of cohesion and chromosome segregation errors

(2016) Adrienne T. Perkins et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Telomeres, Reproductive Aging, and Genomic Instability During Early Development

(2016) David L. Keefe   Reproductive Sciences

C-phycocyanin protects against low fertility by inhibiting reactive oxygen species in aging mice

(2016) Yan-Jiao Li et al.   Oncotarget

Both diet and gene mutation induced obesity affect oocyte quality in mice

(2016) Yan-Jun Hou et al.   Scientific Reports

Melatonin improves age-induced fertility decline and attenuates ovarian mitochondrial oxidative stress in mice

(2016) Chao Song et al.   Scientific Reports

Coenzyme Q10 restores oocyte mitochondrial function and fertility during reproductive aging

(2015) Assaf Ben-Meir et al.   AGING CELL

Resveratrol-induced mitochondrial synthesis and autophagy in oocytes derived from early antral follicles of aged cows

(2015) Miyako SUGIYAMA et al.   JOURNAL OF REPRODUCTION AND DEVELOPMENT

Sirtuin Functions in Female Fertility: Possible Role in Oxidative Stress and Aging

(2015) Carla Tatone et al.   Oxidative Medicine and Cellular Longevity

DNA damage-induced metaphase I arrest is mediated by the spindle assembly checkpoint and maternal age

(2015) Petros Marangos et al.   Nature Communications

Altered Levels of Mitochondrial DNA Are Associated with Female Age, Aneuploidy, and Provide an Independent Measure of Embryonic Implantation Potential

(2015) Elpida Fragouli et al.   PLoS Genetics

Reactive oxygen species and mitochondria: A nexus of cellular homeostasis

(2015) Joe Dan Dunn et al.   Redox Biology

Mitochondrial Fission Factor Drp1 Maintains Oocyte Quality via Dynamic Rearrangement of Multiple Organelles

(2014) Osamu Udagawa et al.   CURRENT BIOLOGY

Dynein-dependent transport of spindle assembly checkpoint proteins off kinetochores toward spindle poles

(2014) Patrícia M.A. Silva et al.   FEBS LETTERS

SIRT1 signalling protects mouse oocytes against oxidative stress and is deregulated during aging

(2014) Giovanna Di Emidio et al.   HUMAN REPRODUCTION

Exome sequencing of senescence-accelerated mice (SAM) reveals deleterious mutations in degenerative disease-causing genes

(2013) Kumpei Tanisawa et al.   BMC GENOMICS

Mitochondrial DNA Rearrangements in Health and Disease-A Comprehensive Study

(2013) Joana Damas et al.   HUMAN MUTATION

The sirtuin family’s role in aging and age-associated pathologies

(2013) Jessica A. Hall et al.   JOURNAL OF CLINICAL INVESTIGATION

Age-associated telomere shortening in mouse oocytes

(2013) Tomoko Yamada-Fukunaga et al.   Reproductive Biology and Endocrinology

Impairment of BRCA1-Related DNA Double-Strand Break Repair Leads to Ovarian Aging in Mice and Humans

(2013) S. Titus et al.   Science Translational Medicine

Induction of Autophagy Promotes Preattachment Development of Bovine Embryos by Reducing Endoplasmic Reticulum Stress1

(2012) Bong-Seok Song et al.   BIOLOGY OF REPRODUCTION

Immunohistochemical and ultrastructural visualization of different routes of oocyte elimination in adult rats

(2012) M.L. Escobar Sánchez et al.   EUROPEAN JOURNAL OF HISTOCHEMISTRY

Seven sirtuins for seven deadly diseases ofaging

(2012) Brian J. Morris   FREE RADICAL BIOLOGY AND MEDICINE

Mitochondrial Fission, Fusion, and Stress

(2012) R. J. Youle et al.   SCIENCE

Oxidative Damage Increases and Antioxidant Gene Expression Decreases with Aging in the Mouse Ovary

(2010) J. Lim et al.   BIOLOGY OF REPRODUCTION

Telomere susceptibility to cigarette smoke-induced oxidative damage and chromosomal instability of mouse embryos in vitro

(2010) Junjiu Huang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Sirt3 protects in vitro–fertilized mouse preimplantation embryos against oxidative stress–induced p53-mediated developmental arrest

(2010) Yumiko Kawamura et al.   JOURNAL OF CLINICAL INVESTIGATION

Mitochondrial function in the human oocyte and embryo and their role in developmental competence

(2010) Jonathan Van Blerkom   MITOCHONDRION

Intrinsic oxidative stress causes either 2-cell arrest or cell death depending on developmental stage of the embryos from SOD1-deficient mice

(2010) N. Kimura et al.   MOLECULAR HUMAN REPRODUCTION

Regulation of autophagy by ROS: physiology and pathology

(2010) Ruth Scherz-Shouval et al.   TRENDS IN BIOCHEMICAL SCIENCES

Ten years of NAD-dependent SIR2 family deacetylases: implications for metabolic diseases

(2010) Shin-ichiro Imai et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Recent progress in the biology and physiology of sirtuins

(2009) Toren Finkel et al.   NATURE

Age-associated increase in aneuploidy and changes in gene expression in mouse eggs

(2008) Hua Pan et al.   DEVELOPMENTAL BIOLOGY

Bovinein vitrooocyte maturation as a model for manipulation of the γ-glutamyl cycle and intraoocyte glutathione

(2008) E. C. Curnow et al.   REPRODUCTION FERTILITY AND DEVELOPMENT

Autophagy Is Essential for Preimplantation Development of Mouse Embryos

(2008) S. Tsukamoto et al.   SCIENCE

Evaluation of the relationship between follicular fluid oxidative stress, ovarian hormones, and response to gonadotropin stimulation

(2007) Malathy Appasamy et al.   FERTILITY AND STERILITY