Technological Challenges and Future Issues for the Detection of Circulating MicroRNAs in Patients With Cancer

µLAS: Sizing of expanded trinucleotide repeats with femtomolar sensitivity in less than 5 minutes

(2019) Rémi Malbec et al.   Scientific Reports

Normalization strategies differently affect circulating miRNA profile associated with the training status

(2019) Martina Faraldi et al.   Scientific Reports

Emergence of MicroRNAs as Key Players in Cancer Cell Metabolism

(2019) Sugarniya Subramaniam et al.   CLINICAL CHEMISTRY

Emerging Function and Clinical Values of Exosomal microRNAs in Cancer

(2019) Man Wang et al.   Molecular Therapy-Nucleic Acids

Liquid Biopsy Approach for Pancreatic Ductal Adenocarcinoma

(2019) Etienne Buscail et al.   Cancers

Detection and localization of surgically resectable cancers with a multi-analyte blood test

(2018) Joshua D. Cohen et al.   SCIENCE

Lateral flow test for visual detection of multiple MicroRNAs

(2018) Wanli Zheng et al.   SENSORS AND ACTUATORS B-CHEMICAL

Spatial Analysis of Nanofluidic-Embedded Biosensors for Wash-Free Single-Nucleotide Difference Discrimination

(2018) Jean Cacheux et al.   ACS Sensors

Towards personalised rapid label free miRNA detection for cancer and liver injury diagnostics in cell lysates and blood based samples

(2018) James Duffy et al.   Nanoscale

Nucleic acid hybridization on an electrically reconfigurable network of gold-coated magnetic nanoparticles enables microRNA detection in blood

(2018) Roya Tavallaie et al.   Nature Nanotechnology

MicroRNA therapeutics: towards a new era for the management of cancer and other diseases

(2017) Rajesha Rupaimoole et al.   NATURE REVIEWS DRUG DISCOVERY

Steps to achieve quantitative measurements of microRNA using two step droplet digital PCR

(2017) Erica V. Stein et al.   PLoS One

PCR-Free, Multiplexed Expression Profiling of microRNAs Using Silicon Photonic Microring Resonators

(2016) Richard M. Graybill et al.   ANALYTICAL CHEMISTRY

High-throughput miRNA sequencing and identification of biomarkers for forensically relevant biological fluids

(2016) Sarah Seashols-Williams et al.   ELECTROPHORESIS

DNA separation and enrichment using electro-hydrodynamic bidirectional flows in viscoelastic liquids

(2016) Hubert Ranchon et al.   LAB ON A CHIP

A methodological procedure for evaluating the impact of hemolysis on circulating microRNAs

(2016) Sara Pizzamiglio et al.   Oncology Letters

Assessing cellular and circulating miRNA recovery: the impact of the RNA isolation method and the quantity of input material

(2016) Victoria El-Khoury et al.   Scientific Reports

Label-Free Nanoplasmonic-Based Short Noncoding RNA Sensing at Attomolar Concentrations Allows for Quantitative and Highly Specific Assay of MicroRNA-10b in Biological Fluids and Circulating Exosomes

(2015) Gayatri K. Joshi et al.   ACS Nano

Detection of microRNA in clinical tumor samples by isothermal enzyme-free amplification and label-free graphene oxide-based SYBR Green I fluorescence platform

(2015) Debin Zhu et al.   BIOSENSORS & BIOELECTRONICS

Optimized microRNA purification from TRIzol-treated plasma

(2015) Janice Duy et al.   BMC GENOMICS

MicroRNAs in cancer: from developmental genes in worms to their clinical application in patients

(2015) M Pichler et al.   BRITISH JOURNAL OF CANCER

On-chip surface acoustic wave lysis and ion-exchange nanomembrane detection of exosomal RNA for pancreatic cancer study and diagnosis

(2015) Daniel Taller et al.   LAB ON A CHIP

First-in-man Phase 1 Clinical Trial of Gene Therapy for Advanced Pancreatic Cancer: Safety, Biodistribution, and Preliminary Clinical Findings

(2015) Louis Buscail et al.   MOLECULAR THERAPY

Circulating microRNA Biomarkers as Liquid Biopsy for Cancer Patients: Pros and Cons of Current Assays

(2015) Shigeshi Ono et al.   Journal of Clinical Medicine

Salivary MicroRNA in Pancreatic Cancer Patients

(2015) Marine Humeau et al.   PLoS One

Methodological challenges in utilizing miRNAs as circulating biomarkers

(2014) Leni Moldovan et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Absolute and Direct MicroRNA Quantification Using DNA–Gold Nanoparticle Probes

(2014) Federica Degliangeli et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

miRNA in Plasma Exosome is Stable under Different Storage Conditions

(2014) Qinyu Ge et al.   MOLECULES

DNA-Conjugated Quantum Dot Nanoprobe for High-Sensitivity Fluorescent Detection of DNA and micro-RNA

(2013) Shao Su et al.   ACS Applied Materials & Interfaces

Designing a Polycationic Probe for Simultaneous Enrichment and Detection of MicroRNAs in a Nanopore

(2013) Kai Tian et al.   ACS Nano

Exosomes: the future of biomarkers in medicine

(2013) Francesca Properzi et al.   Biomarkers in Medicine

Visual detection of microRNA with lateral flow nucleic acid biosensor

(2013) Xuefei Gao et al.   BIOSENSORS & BIOELECTRONICS

Pre-analytical variables in miRNA analysis

(2013) Nils Becker et al.   CLINICAL BIOCHEMISTRY

Optimizing the purification and analysis of miRNAs from urinary exosomes

(2013) Sarath Kiran Channavajjhala et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Multi-Platform Analysis of MicroRNA Expression Measurements in RNA from Fresh Frozen and FFPE Tissues

(2013) Christopher P. Kolbert et al.   PLoS One

Identification of a pan-cancer oncogenic microRNA superfamily anchored by a central core seed motif

(2013) Mark P. Hamilton et al.   Nature Communications

Comparison of Methods for miRNA Extraction from Plasma and Quantitative Recovery of RNA from Cerebrospinal Fluid

(2013) Melissa A. McAlexander et al.   Frontiers in Genetics

Trace and Label-Free MicroRNA Detection Using Oligonucleotide Encapsulated Silver Nanoclusters as Probes

(2012) Haifeng Dong et al.   ANALYTICAL CHEMISTRY

Sample Preparation-Free, Real-Time Detection of microRNA in Human Serum Using Piezoelectric Cantilever Biosensors at Attomole Level

(2012) Blake N. Johnson et al.   ANALYTICAL CHEMISTRY

Electrochemical determination of microRNA-21 based on graphene, LNA integrated molecular beacon, AuNPs and biotin multifunctional bio bar codes and enzymatic assay system

(2012) Huanshun Yin et al.   BIOSENSORS & BIOELECTRONICS

MicroRNA Analysis: Is It Ready for Prime Time?

(2012) G. J. Tsongalis et al.   CLINICAL CHEMISTRY

Impact of serum storage conditions on microRNA stability

(2012) S Grasedieck et al.   LEUKEMIA

Short Structured RNAs with Low GC Content Are Selectively Lost during Extraction from a Small Number of Cells

(2012) Young-Kook Kim et al.   MOLECULAR CELL

Arrays of nanoelectromechanical biosensors functionalized by microcontact printing

(2012) S Salomon et al.   NANOTECHNOLOGY

The Majority of MicroRNAs Detectable in Serum and Saliva Is Concentrated in Exosomes

(2012) Alessia Gallo et al.   PLoS One

Size Matters: Problems and Advantages Associated with Highly Miniaturized Sensors

(2012) Andreas B. Dahlin   SENSORS

An enzyme-linked assay for the rapid quantification of microRNAs based on the viral suppressor of RNA silencing protein p19

(2011) Neda Nasheri et al.   ANALYTICAL BIOCHEMISTRY

Anti-DNA:RNA Antibodies and Silicon Photonic Microring Resonators: Increased Sensitivity for Multiplexed microRNA Detection

(2011) Abraham J. Qavi et al.   ANALYTICAL CHEMISTRY

Amplified Detection of MicroRNA Based on Ruthenium Oxide Nanoparticle-Initiated Deposition of an Insulating Film

(2011) Yanfen Peng et al.   ANALYTICAL CHEMISTRY

A highly sensitive and specific biosensor for ligation- and PCR-free detection of MicroRNAs

(2011) Zhiqiang Gao et al.   BIOSENSORS & BIOELECTRONICS

Blood Cell Origin of Circulating MicroRNAs: A Cautionary Note for Cancer Biomarker Studies

(2011) C. C. Pritchard et al.   Cancer Prevention Research

Post-transcriptional generation of miRNA variants by multiple nucleotidyl transferases contributes to miRNA transcriptome complexity

(2011) S. K. Wyman et al.   GENOME RESEARCH

Non-coding RNAs as theranostics in human cancers

(2011) Roxana S Redis et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Plasma Components Affect Accuracy of Circulating Cancer-Related MicroRNA Quantitation

(2011) Dong-Ja Kim et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

RETRACTED: Cell Adhesion-Dependent Control of MicroRNA Decay

(2011) Young-Kook Kim et al.   MOLECULAR CELL

MicroRNA history: Discovery, recent applications, and next frontiers

(2011) Maria I. Almeida et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Characterization of extracellular circulating microRNA

(2011) Andrey Turchinovich et al.   NUCLEIC ACIDS RESEARCH

Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasma

(2011) J. D. Arroyo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Surface Plasmon Resonance Biosensor for Rapid Label-Free Detection of Microribonucleic Acid at Subfemtomole Level

(2010) Hana Šípová et al.   ANALYTICAL CHEMISTRY

Epigenetic Silencing of miR-137 Is an Early Event in Colorectal Carcinogenesis

(2010) F. Balaguer et al.   CANCER RESEARCH

Circulating microRNA in body fluid: a new potential biomarker for cancer diagnosis and prognosis

(2010) Nobuyoshi Kosaka et al.   CANCER SCIENCE

The Silencing of MicroRNA 148a Production by DNA Hypermethylation Is an Early Event in Pancreatic Carcinogenesis

(2010) N. Hanoun et al.   CLINICAL CHEMISTRY

Many ways to generate microRNA-like small RNAs: non-canonical pathways for microRNA production

(2010) Keita Miyoshi et al.   MOLECULAR GENETICS AND GENOMICS

MicroRNA isolation and stability in stored RNA samples

(2009) M. Mraz et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Label-free direct detection of MiRNAs with silicon nanowire biosensors

(2009) Guo-Jun Zhang et al.   BIOSENSORS & BIOELECTRONICS

Biogenesis of small RNAs in animals

(2009) V. Narry Kim et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Interaction of biomolecules sequentially deposited at the same location using a microcantilever-based spotter

(2008) Nathalie Berthet-Duroure et al.   BIOMEDICAL MICRODEVICES

Detection of elevated levels of tumour-associated microRNAs in serum of patients with diffuse large B-cell lymphoma

(2008) Charles H. Lawrie et al.   BRITISH JOURNAL OF HAEMATOLOGY

Evaluation and Validation of Total RNA Extraction Methods for MicroRNA Expression Analyses in Formalin-Fixed, Paraffin-Embedded Tissues

(2008) Martina Doleshal et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

Detection of microRNA Expression in Human Peripheral Blood Microvesicles

(2008) Melissa Piper Hunter et al.   PLoS One

Circulating microRNAs as stable blood-based markers for cancer detection

(2008) P. S. Mitchell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA