Methylene Blue Reduces Neuronal Apoptosis and Improves Blood-Brain Barrier Integrity After Traumatic Brain Injury

SS-31 Provides Neuroprotection by Reversing Mitochondrial Dysfunction after Traumatic Brain Injury

(2018) Yihao Zhu et al.   Oxidative Medicine and Cellular Longevity

Blood-Brain Barrier: From Physiology to Disease and Back

(2018) Melanie D. Sweeney et al.   PHYSIOLOGICAL REVIEWS

Anti-inflammatory and immunomodulatory mechanisms of atorvastatin in a murine model of traumatic brain injury

(2017) Xin Xu et al.   Journal of Neuroinflammation

Synaptic Mitochondria Sustain More Damage than Non-Synaptic Mitochondria after Traumatic Brain Injury and Are Protected by Cyclosporine A

(2017) Jacqueline R. Kulbe et al.   JOURNAL OF NEUROTRAUMA

From Mitochondrial Function to Neuroprotection—an Emerging Role for Methylene Blue

(2017) Donovan Tucker et al.   MOLECULAR NEUROBIOLOGY

Mitochondrial DNA and primary mitochondrial dysfunction in Parkinson's disease

(2017) Maria Pia Giannoccaro et al.   MOVEMENT DISORDERS

Mitochondria and microRNA crosstalk in traumatic brain injury

(2017) Wang-Xia Wang et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Protective Role of Methylene Blue in Alzheimer's Disease via Mitochondria and Cytochrome c Oxidase

(2017) Hani Atamna et al.   JOURNAL OF ALZHEIMERS DISEASE

Predicting Intracranial Pressure and Brain Tissue Oxygen Crises in Patients With Severe Traumatic Brain Injury

(2016) Risa B. Myers et al.   CRITICAL CARE MEDICINE

Delayed Methylene Blue Improves Lesion Volume, Multi-Parametric Quantitative Magnetic Resonance Imaging Measurements, and Behavioral Outcome after Traumatic Brain Injury

(2016) Lora Talley Watts et al.   JOURNAL OF NEUROTRAUMA

Melatonin attenuates neuronal apoptosis through up-regulation of K+-Cl−cotransporter KCC2 expression following traumatic brain injury in rats

(2016) Haijian Wu et al.   JOURNAL OF PINEAL RESEARCH

Transfer of mitochondria from astrocytes to neurons after stroke

(2016) Kazuhide Hayakawa et al.   NATURE

Dual effects of carbon monoxide on pericytes and neurogenesis in traumatic brain injury

(2016) Yoon Kyung Choi et al.   NATURE MEDICINE

Epigenetic changes following traumatic brain injury and their implications for outcome, recovery and therapy

(2016) Victor S. Wong et al.   NEUROSCIENCE LETTERS

TIA1 oxidation inhibits stress granule assembly and sensitizes cells to stress-induced apoptosis

(2016) Kyoko Arimoto-Matsuzaki et al.   Nature Communications

Traumatic Brain Injury and Mitochondrial Dysfunction

(2015) John B. Hiebert et al.   AMERICAN JOURNAL OF THE MEDICAL SCIENCES

Methylene Blue Attenuates Traumatic Brain Injury-Associated Neuroinflammation and Acute Depressive-Like Behavior in Mice

(2015) Ashley M. Fenn et al.   JOURNAL OF NEUROTRAUMA

Methylene blue exerts a neuroprotective effect against traumatic brain injury by promoting autophagy and inhibiting microglial activation

(2015) MINGFEI ZHAO et al.   Molecular Medicine Reports

Anatomy and physiology of the blood–brain barrier

(2015) Yonatan Serlin et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Methylene blue treatment delays progression of perfusion–diffusion mismatch to infarct in permanent ischemic stroke

(2014) Pavel Rodriguez et al.   BRAIN RESEARCH

Methylene Blue Is Neuroprotective against Mild Traumatic Brain Injury

(2014) Lora Talley Watts et al.   JOURNAL OF NEUROTRAUMA

Induction of oxidative and nitrosative damage leads to cerebrovascular inflammation in an animal model of mild traumatic brain injury induced by primary blast

(2013) P.M. Abdul-Muneer et al.   FREE RADICAL BIOLOGY AND MEDICINE

Changing patterns in the epidemiology of traumatic brain injury

(2013) Bob Roozenbeek et al.   Nature Reviews Neurology

Therapeutic and preventive effects of methylene blue on Alzheimer's disease pathology in a transgenic mouse model

(2013) V. Paban et al.   NEUROPHARMACOLOGY

Neuroprotective Efficacy of Methylene Blue in Ischemic Stroke: An MRI Study

(2013) Qiang Shen et al.   PLoS One

Mitochondria in traumatic brain injury and mitochondrial-targeted multipotential therapeutic strategies

(2012) Gang Cheng et al.   BRITISH JOURNAL OF PHARMACOLOGY

Alternative Mitochondrial Electron Transfer as a Novel Strategy for Neuroprotection

(2011) Yi Wen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of Bcl-2 family proteins and caspases in the regulation of apoptosis

(2011) Mohammad Shamsul Ola et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Involvement of ROS in BBB dysfunction

(2009) Pamela B. L. Pun et al.   FREE RADICAL RESEARCH

Alterations in Blood-Brain Barrier Permeability to Large and Small Molecules and Leukocyte Accumulation after Traumatic Brain Injury: Effects of Post-Traumatic Hypothermia

(2009) George Lotocki et al.   JOURNAL OF NEUROTRAUMA

Something Old... Something Blue

(2009) S. Scheindlin   MOLECULAR INTERVENTIONS

Methylene blue delays cellular senescence and enhances key mitochondrial biochemical pathways

(2007) Hani Atamna et al.   FASEB JOURNAL