LNDriver: identifying driver genes by integrating mutation and expression data based on gene-gene interaction network

Integration of somatic mutation, expression and functional data reveals potential driver genes predictive of breast cancer survival

(2015) Chen Suo et al.   BIOINFORMATICS

Advances in computational approaches for prioritizing driver mutations and significantly mutated genes in cancer genomes

(2015) Feixiong Cheng et al.   BRIEFINGS IN BIOINFORMATICS

Comprehensive genomic characterization of head and neck squamous cell carcinomas

(2015)   NATURE

An Evolutionary Approach for Identifying Driver Mutations in Colorectal Cancer

(2015) Jasmine Foo et al.   PLoS Computational Biology

SHP2E76K mutant promotes lung tumorigenesis in transgenic mice

(2014) Valentina E. Schneeberger et al.   CARCINOGENESIS

Tyrosine phosphatase SHP2 increases cell motility in triple-negative breast cancer through the activation of SRC-family kinases

(2014) N Sausgruber et al.   ONCOGENE

VarWalker: Personalized Mutation Network Analysis of Putative Cancer Genes from Next-Generation Sequencing Data

(2014) Peilin Jia et al.   PLoS Computational Biology

Long noncoding RNAHOTAIRis relevant to cellular proliferation, invasiveness, and clinical relapse in small-cell lung cancer

(2014) Hiroshi Ono et al.   Cancer Medicine

Identification of mutated core cancer modules by integrating somatic mutation, copy number variation, and gene expression data

(2013) Junhua Zhang et al.   BMC Systems Biology

RB1 in cancer: Different mechanisms of RB1 inactivation and alterations of pRb pathway in tumorigenesis

(2013) Riccardo Di Fiore et al.   JOURNAL OF CELLULAR PHYSIOLOGY

DriverNet: uncovering the impact of somatic driver mutations on transcriptional networks in cancer

(2013) Ali Bashashati et al.   GENOME BIOLOGY

Efficient methods for identifying mutated driver pathways in cancer

(2012) Junfei Zhao et al.   BIOINFORMATICS

MuSiC: Identifying mutational significance in cancer genomes

(2012) N. D. Dees et al.   GENOME RESEARCH

Sequence analysis of mutations and translocations across breast cancer subtypes

(2012) Shantanu Banerji et al.   NATURE

Comprehensive genomic characterization of squamous cell lung cancers

(2012)   NATURE

Functional impact bias reveals cancer drivers

(2012) Abel Gonzalez-Perez et al.   NUCLEIC ACIDS RESEARCH

Metasample-Based Sparse Representation for Tumor Classification

(2011) Chun-Hou Zheng et al.   IEEE-ACM Transactions on Computational Biology and Bioinformatics

Molecular Pattern Discovery Based on Penalized Matrix Decomposition

(2011) Chun-Hou Zheng et al.   IEEE-ACM Transactions on Computational Biology and Bioinformatics

The expression of phospho-AKT1 and phospho-MTOR is associated with a favorable prognosis independent of PTEN expression in intrahepatic cholangiocarcinomas

(2011) Dakeun Lee et al.   MODERN PATHOLOGY

Exome Sequencing of Head and Neck Squamous Cell Carcinoma Reveals Inactivating Mutations in NOTCH1

(2011) N. Agrawal et al.   SCIENCE

Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation

(2010) Ramin Nazarian et al.   NATURE

International network of cancer genome projects

(2010) Thomas J. Hudson (Chairperson) et al.   NATURE

A method and server for predicting damaging missense mutations

(2010) Ivan A Adzhubei et al.   NATURE METHODS

The RASopathies: developmental syndromes of Ras/MAPK pathway dysregulation

(2009) William E Tidyman et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Amplification and overexpression ofPPFIA1, a putative 11q13 invasion suppressor gene, in head and neck squamous cell carcinoma

(2008) Kaia Davis Tan et al.   GENES CHROMOSOMES & CANCER

Somatic mutations affect key pathways in lung adenocarcinoma

(2008) Li Ding et al.   NATURE

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

(2008) Roger McLendon et al.   NATURE

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

(2008) Da Wei Huang et al.   NUCLEIC ACIDS RESEARCH

Human Protein Reference Database--2009 update

(2008) T. S. Keshava Prasad et al.   NUCLEIC ACIDS RESEARCH

Core Signaling Pathways in Human Pancreatic Cancers Revealed by Global Genomic Analyses

(2008) S. Jones et al.   SCIENCE