RB1 in cancer: Different mechanisms of RB1 inactivation and alterations of pRb pathway in tumorigenesis

Molecular Changes in Mesothelioma With an Impact on Prognosis and Treatment

(2012) Didier Jean et al.   ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE

Perturbation of Rb, p53, and Brca1 or Brca2 Cooperate in Inducing Metastatic Serous Epithelial Ovarian Cancer

(2012) Ludmila Szabova et al.   CANCER RESEARCH

Emerging insights into the molecular and cellular basis of glioblastoma

(2012) G. P. Dunn et al.   GENES & DEVELOPMENT

Induction of ZEB Proteins by Inactivation of RB Protein Is Key Determinant of Mesenchymal Phenotype of Breast Cancer

(2012) Yoshimi Arima et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dissecting Pin1 and phospho-pRb regulation

(2012) Flavio Rizzolio et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Cooperation between Rb and Arf in suppressing mouse retinoblastoma

(2012) Karina Conkrite et al.   JOURNAL OF CLINICAL INVESTIGATION

NEDDylation controls the target specificity of E2F1 and apoptosis induction

(2012) I Aoki et al.   ONCOGENE

A cluster of cooperating tumor-suppressor gene candidates in chromosomal deletions

(2012) W. Xue et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The retinoblastoma family of proteins and their regulatory functions in the mammalian cell division cycle

(2012) Shauna A Henley et al.   Cell Division

E2F2 represses cell cycle regulators to maintain quiescence

(2011) Arantza Infante et al.   CELL CYCLE

Making sense of cancer genomic data

(2011) Lynda Chin et al.   GENES & DEVELOPMENT

Downregulation of CDKN2A and Suppression of Cyclin D1 Gene Expressions in Malignant Gliomas

(2011) Weidong Liu et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

E2F7 represses a network of oscillating cell cycle genes to control S-phase progression

(2011) Bart Westendorp et al.   NUCLEIC ACIDS RESEARCH

E2F5 status significantly improves malignancy diagnosis of epithelial ovarian cancer

(2010) Narasimhan Kothandaraman et al.   BMC CANCER

E2F8 Contributes to Human Hepatocellular Carcinoma via Regulating Cell Proliferation

(2010) Q. Deng et al.   CANCER RESEARCH

RB's original CIN?

(2010) J. Sage et al.   GENES & DEVELOPMENT

The E2F5 repressor is an activator of E6/E7 transcription and of the S-phase entry in HPV18-associated cells

(2010) S Teissier et al.   ONCOGENE

E2F1-Mediated Apoptosis as a Target of Cancer Therapy

(2010) Zhenlong Wu et al.   Current Molecular Pharmacology

Deficiency of pRb Family Proteins and p53 in Invasive Urothelial Tumorigenesis

(2009) F. He et al.   CANCER RESEARCH

Paclitaxel and beta-lapachone synergistically induce apoptosis in human retinoblastoma Y79 cells by downregulating the levels of phospho-Akt

(2009) Antonella D'Anneo et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Cdk2 and Cdk4 Regulate the Centrosome Cycle and Are Critical Mediators of Centrosome Amplification in p53-Null Cells

(2009) A. M. Adon et al.   MOLECULAR AND CELLULAR BIOLOGY

E2f1–3 switch from activators in progenitor cells to repressors in differentiating cells

(2009) Jean-Leon Chong et al.   NATURE

Modeling the effect of the RB tumor suppressor on disease progression: dependence on oncogene network and cellular context

(2009) J L Dean et al.   ONCOGENE

Atypical E2Fs: new players in the E2F transcription factor family

(2009) Tim Lammens et al.   TRENDS IN CELL BIOLOGY

How the Rb tumor suppressor structure and function was revealed by the study of Adenovirus and SV40

(2009) James A. DeCaprio   VIROLOGY

Cyclin D1 Overexpression, p16 Loss, and pRb Inactivation Play a Key Role in Pulmonary Carcinogenesis and have a Prognostic Implication for the Long-term Survival in Non-small Cell Lung Carcinoma Patients

(2009) Na-Hye Myong   Cancer Research and Treatment

Cancer risk in patients with constitutional chromosome deletions: a nationwide British cohort study

(2008) A J Swerdlow et al.   BRITISH JOURNAL OF CANCER

Rb Depletion Results in Deregulation of E-Cadherin and Induction of Cellular Phenotypic Changes that Are Characteristic of the Epithelial-to-Mesenchymal Transition

(2008) Y. Arima et al.   CANCER RESEARCH

The Retinoblastoma Family Member pRb2/p130 Is an Independent Predictor of Survival in Human Soft Tissue Sarcomas

(2008) V. Masciullo et al.   CLINICAL CANCER RESEARCH

E2F7 and E2F8 Keep the E2F Family in Balance

(2008) Nam-Sung Moon et al.   DEVELOPMENTAL CELL

Synergistic Function of E2F7 and E2F8 Is Essential for Cell Survival and Embryonic Development

(2008) Jing Li et al.   DEVELOPMENTAL CELL

Loss of RB1 induces non-proliferative retinoma: increasing genomic instability correlates with progression to retinoblastoma

(2008) Helen Dimaras et al.   HUMAN MOLECULAR GENETICS

G1 to S phase cell cycle transition in somatic and embryonic stem cells

(2008) Irina Neganova et al.   JOURNAL OF ANATOMY

Loss of 9p leads to p16INK4A down-regulation and enables RB/E2F1-dependent cell cycle promotion in gastrointestinal stromal tumours (GISTs)

(2008) F Haller et al.   JOURNAL OF PATHOLOGY

The Retinoblastoma Protein Tumor Suppressor Is Important for Appropriate Osteoblast Differentiation and Bone Development

(2008) S. D. Berman et al.   MOLECULAR CANCER RESEARCH

Inhibition of pituitary tumors in Rb mutant chimeras through E2f4 loss reveals a key suppressive role for the pRB/E2F pathway in urothelium and ganglionic carcinogenesis

(2008) T Parisi et al.   ONCOGENE

Insights from mouse models into human retinoblastoma

(2008) David MacPherson   Cell Division