Structure biology of selective autophagy receptors

The receptor proteins: pivotal roles in selective autophagy

(2015) Zhijie Xu et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Molecular basis of ubiquitin recognition by the autophagy receptor CALCOCO2

(2015) Xingqiao Xie et al.   Autophagy

Amino-terminal arginylation as a degradation signal for selective autophagy

(2015) Hyunjoo Cha-Molstad et al.   BMB Reports

Swapping of interaction partners with ATG5 for autophagosome maturation

(2015) Jun Hoe Kim et al.   BMB Reports

p62/SQSTM1 functions as a signaling hub and an autophagy adaptor

(2015) Yoshinori Katsuragi et al.   FEBS Journal

Post-translationally-modified structures in the autophagy machinery: an integrative perspective

(2015) Hana Popelka et al.   FEBS Journal

Autophagy receptor defects and ALS-FTLD

(2015) Veronika Majcher et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Cryo-EM: A Unique Tool for the Visualization of Macromolecular Complexity

(2015) Eva Nogales et al.   MOLECULAR CELL

The PINK1-PARKIN Mitochondrial Ubiquitylation Pathway Drives a Program of OPTN/NDP52 Recruitment and TBK1 Activation to Promote Mitophagy

(2015) Jin-Mi Heo et al.   MOLECULAR CELL

Regulation of endoplasmic reticulum turnover by selective autophagy

(2015) Aliaksandr Khaminets et al.   NATURE

Receptor-mediated selective autophagy degrades the endoplasmic reticulum and the nucleus

(2015) Keisuke Mochida et al.   NATURE

The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy

(2015) Michael Lazarou et al.   NATURE

Amino-terminal arginylation targets endoplasmic reticulum chaperone BiP for autophagy through p62 binding

(2015) Hyunjoo Cha-Molstad et al.   NATURE CELL BIOLOGY

Structure of the Atg101–Atg13 complex reveals essential roles of Atg101 in autophagy initiation

(2015) Hironori Suzuki et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structure of the Atg101–Atg13 complex reveals essential roles of Atg101 in autophagy initiation

(2015) Hironori Suzuki et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The Selective Autophagy Receptor p62 Forms a Flexible Filamentous Helical Scaffold

(2015) Rodolfo Ciuffa et al.   Cell Reports

A Designed Conformational Shift To Control Protein Binding Specificity

(2014) Servaas Michielssens et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Autophagy revisited: A conversation with Christian de Duve

(2014) Daniel J. Klionsky   Autophagy

Insights into autophagosome maturation revealed by the structures of ATG5 with its interacting partners

(2014) Jun Hoe Kim et al.   Autophagy

Autophagic Clearance of PolyQ Proteins Mediated by Ubiquitin-Atg8 Adaptors of the Conserved CUET Protein Family

(2014) Kefeng Lu et al.   CELL

Atomistic Autophagy: The Structures of Cellular Self-Digestion

(2014) James H. Hurley et al.   CELL

Solution Structure of the Ubiquitin-associated (UBA) Domain of Human Autophagy Receptor NBR1 and Its Interaction with Ubiquitin and Polyubiquitin

(2014) Erik Walinda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dynamic regulation of macroautophagy by distinctive ubiquitin-like proteins

(2014) Daniel J Klionsky et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural basis of starvation-induced assembly of the autophagy initiation complex

(2014) Yuko Fujioka et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Optineurin is an autophagy receptor for damaged mitochondria in parkin-mediated mitophagy that is disrupted by an ALS-linked mutation

(2014) Yvette C. Wong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Super-Resolution in Solution X-Ray Scattering and Its Applications to Structural Systems Biology

(2013) Robert P. Rambo et al.   Annual Review of Biophysics

Structures of Atg7-Atg3 and Atg7-Atg10 reveal noncanonical mechanisms of E2 recruitment by the autophagy E1

(2013) Stephen E. Kaiser et al.   Autophagy

Structural basis for phosphorylation-triggered autophagic clearance ofSalmonella

(2013) Vladimir V. Rogov et al.   BIOCHEMICAL JOURNAL

Historical landmarks of autophagy research

(2013) Yoshinori Ohsumi   CELL RESEARCH

The Atg8 family: multifunctional ubiquitin-like key regulators of autophagy

(2013) Moran Rawet Slobodkin et al.   Essays in Biochemistry

The LC3 interactome at a glance

(2013) P. Wild et al.   JOURNAL OF CELL SCIENCE

Phosphorylation of p62 Activates the Keap1-Nrf2 Pathway during Selective Autophagy

(2013) Yoshinobu Ichimura et al.   MOLECULAR CELL

Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization

(2013) Shireen A. Sarraf et al.   NATURE

The ubiquitin ligase parkin mediates resistance to intracellular pathogens

(2013) Paolo S. Manzanillo et al.   NATURE

Structural and biochemical insights into the homotypic PB1-PB1 complex between PKCζ and p62

(2013) Jun Ren et al.   Science China-Life Sciences

A Correction to the Editors' Choice Summary Titled "Not So Different After All" by Annalisa M. VanHook

(2013)   Science Signaling

Structural basis for recognition of autophagic receptor NDP52 by the sugar receptor galectin-8

(2013) Byeong-Won Kim et al.   Nature Communications

Structure of the autophagic E2 enzyme Atg10

(2012) Seung Beom Hong et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Extracellular M. tuberculosis DNA Targets Bacteria for Autophagy by Activating the Host DNA-Sensing Pathway

(2012) Robert O. Watson et al.   CELL

Ubiquitination and selective autophagy

(2012) S Shaid et al.   CELL DEATH AND DIFFERENTIATION

Microtubule-associated Protein 1 Light Chain 3 (LC3) Interacts with Bnip3 Protein to Selectively Remove Endoplasmic Reticulum and Mitochondria via Autophagy

(2012) Rita A. Hanna et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ubiquitin-independent function of optineurin in autophagic clearance of protein aggregates

(2012) J. Korac et al.   JOURNAL OF CELL SCIENCE

NBR1 acts as an autophagy receptor for peroxisomes

(2012) E. Deosaran et al.   JOURNAL OF CELL SCIENCE

LC3C, Bound Selectively by a Noncanonical LIR Motif in NDP52, Is Required for Antibacterial Autophagy

(2012) Natalia von Muhlinen et al.   MOLECULAR CELL

Galectin 8 targets damaged vesicles for autophagy to defend cells against bacterial invasion

(2012) Teresa L. M. Thurston et al.   NATURE

Autophagy receptors link myosin VI to autophagosomes to mediate Tom1-dependent autophagosome maturation and fusion with the lysosome

(2012) David A. Tumbarello et al.   NATURE CELL BIOLOGY

Noncanonical E2 recruitment by the autophagy E1 revealed by Atg7–Atg3 and Atg7–Atg10 structures

(2012) Stephen E Kaiser et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Starch-binding domain-containing protein 1 (Stbd1) and glycogen metabolism: Identification of the Atg8 family interacting motif (AIM) in Stbd1 required for interaction with GABARAPL1

(2011) Sixin Jiang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

NBR1 and p62 as cargo receptors for selective autophagy of ubiquitinated targets

(2011) Trond Lamark et al.   CELL CYCLE

Crystal Structure of the Ubiquitin-associated (UBA) Domain of p62 and Its Interaction with Ubiquitin

(2011) Shin Isogai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

p62 and NDP52 Proteins Target IntracytosolicShigellaandListeriato Different Autophagy Pathways

(2011) Serge Mostowy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Characterization of the Interaction of GABARAPL-1 with the LIR Motif of NBR1

(2011) Alexis Rozenknop et al.   JOURNAL OF MOLECULAR BIOLOGY

Autophagy in immunity and inflammation

(2011) Beth Levine et al.   NATURE

Insights into noncanonical E1 enzyme activation from the structure of autophagic E1 Atg7 with Atg8

(2011) Seung Beom Hong et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Phosphorylation of the Autophagy Receptor Optineurin Restricts Salmonella Growth

(2011) P. Wild et al.   SCIENCE

Antigen Potency and Maximal Efficacy Reveal a Mechanism of Efficient T Cell Activation

(2011) O. Dushek et al.   Science Signaling

Bnip3-mediated mitochondrial autophagy is independent of the mitochondrial permeability transition pore

(2010) Melissa N. Quinsay et al.   Autophagy

Nix: A receptor protein for mitophagy in mammals

(2010) Tomotake Kanki   Autophagy

LC3 and GATE-16/GABARAP subfamilies are both essential yet act differently in autophagosome biogenesis

(2010) Hilla Weidberg et al.   EMBO JOURNAL

Atg8-family interacting motif crucial for selective autophagy

(2010) Nobuo N. Noda et al.   FEBS LETTERS

p62/SQSTM1Is a Target Gene for Transcription Factor NRF2 and Creates a Positive Feedback Loop by Inducing Antioxidant Response Element-driven Gene Transcription

(2010) Ashish Jain et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PCS-based structure determination of protein–protein complexes

(2010) Tomohide Saio et al.   JOURNAL OF BIOMOLECULAR NMR

Network organization of the human autophagy system

(2010) Christian Behrends et al.   NATURE

Selective autophagy: ubiquitin-mediated recognition and beyond

(2010) Claudine Kraft et al.   NATURE CELL BIOLOGY

Eaten alive: a history of macroautophagy

(2010) Zhifen Yang et al.   NATURE CELL BIOLOGY

Role of BNIP3 and NIX in cell death, autophagy and mitophagy

(2009) J Zhang et al.   CELL DEATH AND DIFFERENTIATION

Atg32 Is a Mitochondrial Protein that Confers Selectivity during Mitophagy

(2009) Tomotake Kanki et al.   DEVELOPMENTAL CELL

Mitochondria-Anchored Receptor Atg32 Mediates Degradation of Mitochondria via Selective Autophagy

(2009) Koji Okamoto et al.   DEVELOPMENTAL CELL

Nix is a selective autophagy receptor for mitochondrial clearance

(2009) Ivana Novak et al.   EMBO REPORTS

The NMR structure of the p62 PB1 domain, a key protein in autophagy and NF-κB signaling pathway

(2009) Tomohide Saio et al.   JOURNAL OF BIOMOLECULAR NMR

The Adaptor Protein p62/SQSTM1 Targets Invading Bacteria to the Autophagy Pathway

(2009) Y. T. Zheng et al.   JOURNAL OF IMMUNOLOGY

Dimerisation of the UBA Domain of p62 Inhibits Ubiquitin Binding and Regulates NF-κB Signalling

(2009) Jed Long et al.   JOURNAL OF MOLECULAR BIOLOGY

A Role for Ubiquitin in Selective Autophagy

(2009) Vladimir Kirkin et al.   MOLECULAR CELL

A Role for NBR1 in Autophagosomal Degradation of Ubiquitinated Substrates

(2009) Vladimir Kirkin et al.   MOLECULAR CELL

Autophagy regulates lipid metabolism

(2009) Rajat Singh et al.   NATURE

Mutations in FAM134B, encoding a newly identified Golgi protein, cause severe sensory and autonomic neuropathy

(2009) Ingo Kurth et al.   NATURE GENETICS

The TBK1 adaptor and autophagy receptor NDP52 restricts the proliferation of ubiquitin-coated bacteria

(2009) Teresa L M Thurston et al.   NATURE IMMUNOLOGY

Dynamics and diversity in autophagy mechanisms: lessons from yeast

(2009) Hitoshi Nakatogawa et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Structural basis of target recognition by Atg8/LC3 during selective autophagy

(2008) Nobuo N. Noda et al.   GENES TO CELLS

Structural Basis for Sorting Mechanism of p62 in Selective Autophagy

(2008) Yoshinobu Ichimura et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mature ribosomes are selectively degraded upon starvation by an autophagy pathway requiring the Ubp3p/Bre5p ubiquitin protease

(2008) Claudine Kraft et al.   NATURE CELL BIOLOGY

Conformation and dynamics of the three-helix bundle UBA domain of p62 from experiment and simulation

(2007) Clare-Louise Evans et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS