Antigen Potency and Maximal Efficacy Reveal a Mechanism of Efficient T Cell Activation
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Title
Antigen Potency and Maximal Efficacy Reveal a Mechanism of Efficient T Cell Activation
Authors
Keywords
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Journal
Science Signaling
Volume 4, Issue 176, Pages ra39-ra39
Publisher
American Association for the Advancement of Science (AAAS)
Online
2011-06-08
DOI
10.1126/scisignal.2001430
References
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Related references
Note: Only part of the references are listed.- Single and Dual Amino Acid Substitutions in TCR CDRs Can Enhance Antigen-Specific T Cell Functions
- (2014) Paul F. Robbins et al. JOURNAL OF IMMUNOLOGY
- Strength of TCR-Peptide/MHC Interactions and In Vivo T Cell Responses
- (2011) E. Corse et al. JOURNAL OF IMMUNOLOGY
- Dependence of T Cell Antigen Recognition on T Cell Receptor-Peptide MHC Confinement Time
- (2010) Milos Aleksic et al. IMMUNITY
- TCR ligand density and affinity determine peripheral induction of Foxp3 in vivo
- (2010) Rachel A. Gottschalk et al. JOURNAL OF EXPERIMENTAL MEDICINE
- The kinetics of two-dimensional TCR and pMHC interactions determine T-cell responsiveness
- (2010) Jun Huang et al. NATURE
- TCR–peptide–MHC interactions in situ show accelerated kinetics and increased affinity
- (2010) Johannes B. Huppa et al. NATURE
- Fast on-rates allow short dwell time ligands to activate T cells
- (2010) C. C. Govern et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Goldilocks Model for TCR—Too Much Attraction Might Not Be Best for Vaccine Design
- (2010) Jill E. Slansky et al. PLOS BIOLOGY
- Attenuated T Cell Responses to a High-Potency Ligand In Vivo
- (2010) Emily Corse et al. PLOS BIOLOGY
- T Cell Activation
- (2009) Jennifer E. Smith-Garvin et al. Annual Review of Immunology
- Digital Signaling and Hysteresis Characterize Ras Activation in Lymphoid Cells
- (2009) Jayajit Das et al. CELL
- The Impact of TCR-Binding Properties and Antigen Presentation Format on T Cell Responsiveness
- (2009) A. S. Chervin et al. JOURNAL OF IMMUNOLOGY
- A Role for Rebinding in Rapid and Reliable T Cell Responses to Antigen
- (2009) Omer Dushek et al. PLoS Computational Biology
- Studying Molecular Interactions at the Single Bond Level with a Laminar Flow Chamber
- (2008) Anne Pierres et al. Cellular and Molecular Bioengineering
- Control of HIV-1 immune escape by CD8 T cells expressing enhanced T-cell receptor
- (2008) Angel Varela-Rohena et al. NATURE MEDICINE
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