Beyond T Cells: Understanding the Role of PD-1/PD-L1 in Tumor-Associated Macrophages
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Title
Beyond T Cells: Understanding the Role of PD-1/PD-L1 in Tumor-Associated Macrophages
Authors
Keywords
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Journal
Journal of Immunology Research
Volume 2019, Issue -, Pages 1-7
Publisher
Hindawi Limited
Online
2019-11-05
DOI
10.1155/2019/1919082
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Note: Only part of the references are listed.- Tumour-associated macrophages-derived CXCL8 determines immune evasion through autonomous PD-L1 expression in gastric cancer
- (2019) Chao Lin et al. GUT
- Human tumor-associated monocytes/macrophages and their regulation of T cell responses in early-stage lung cancer
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- Nivolumab Versus Docetaxel in a Predominantly Chinese Patient Population With Previously Treated Advanced NSCLC: CheckMate 078 Randomized Phase III Clinical Trial
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- Restriction of PD-1 function by cis-PD-L1/CD80 interactions is required for optimal T cell responses
- (2019) Daisuke Sugiura et al. SCIENCE
- Pembrolizumab in patients with advanced non-small-cell lung cancer (KEYNOTE-001): 3-year results from an open-label, phase 1 study
- (2019) Natasha B Leighl et al. Lancet Respiratory Medicine
- Amphotericin B suppresses M2 phenotypes and B7-H1 expression in macrophages to prevent Raji cell proliferation
- (2018) Jing Zhang et al. BMC CANCER
- Expression patterns of programmed death ligand 1 correlate with different microenvironments and patient prognosis in hepatocellular carcinoma
- (2018) Chao-Qun Liu et al. BRITISH JOURNAL OF CANCER
- Combined blockade of IL-6 and PD-1/PD-L1 signaling abrogates mutual regulation of their immunosuppressive effects in the tumor microenvironment
- (2018) Hirotake Tsukamoto et al. CANCER RESEARCH
- The Role of Tumor-Associated Macrophages in Colorectal Carcinoma Progression
- (2018) Xiaoming Zhong et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- PD-L1+ tumor-associated macrophages and PD-1+ tumor infiltrating lymphocytes predict survival in primary testicular lymphoma
- (2018) Marjukka Pollari et al. HAEMATOLOGICA
- Regulation and Function of the PD-L1 Checkpoint
- (2018) Chong Sun et al. IMMUNITY
- The effect of IκK-16 on lipopolysaccharide-induced impaired monocytes
- (2018) Norman J. Galbraith et al. IMMUNOBIOLOGY
- PD-L1+ tumor-associated macrophages and PD-1+ tumor infiltrating lymphocytes predict survival in primary testicular lymphoma
- (2018) Marjukka Pollari et al. HAEMATOLOGICA
- PD-L1 binds to B7-1 only in cis on the same cell surface
- (2018) Apoorvi Chaudhri et al. Cancer Immunology Research
- Programmed Cell Death Ligand 1 (PD-L1) Signaling Regulates Macrophage Proliferation and Activation
- (2018) Genevieve P Hartley et al. Cancer Immunology Research
- Anti-PD-1 therapy redirects macrophages from an M2 to an M1 phenotype inducing regression of OS lung metastases
- (2018) Pooja Dhupkar et al. Cancer Medicine
- Glioblastoma stem cell-derived exosomes induce M2 macrophages and PD-L1 expression on human monocytes
- (2018) Konrad Gabrusiewicz et al. OncoImmunology
- Dual role of macrophage in tumor immunity
- (2018) Ryota Tamura et al. Immunotherapy
- Immune cell subset differentiation and tissue inflammation
- (2018) Pu Fang et al. Journal of Hematology & Oncology
- Tumor cell-released autophagosomes (TRAPs) promote immunosuppression through induction of M2-like macrophages with increased expression of PD-L1
- (2018) Zhi-Fa Wen et al. Journal for ImmunoTherapy of Cancer
- Cancer immunotherapy targeting the CD47/SIRPα axis
- (2017) Kipp Weiskopf EUROPEAN JOURNAL OF CANCER
- Upregulation of PD-L1 by SPP1 mediates macrophage polarization and facilitates immune escape in lung adenocarcinoma
- (2017) Yan Zhang et al. EXPERIMENTAL CELL RESEARCH
- Nivolumab Versus Docetaxel in Previously Treated Patients With Advanced Non–Small-Cell Lung Cancer: Two-Year Outcomes From Two Randomized, Open-Label, Phase III Trials (CheckMate 017 and CheckMate 057)
- (2017) Leora Horn et al. JOURNAL OF CLINICAL ONCOLOGY
- Nivolumab in patients with advanced gastric or gastro-oesophageal junction cancer refractory to, or intolerant of, at least two previous chemotherapy regimens (ONO-4538-12, ATTRACTION-2): a randomised, double-blind, placebo-controlled, phase 3 trial
- (2017) Yoon-Koo Kang et al. LANCET
- PD-1 expression by tumour-associated macrophages inhibits phagocytosis and tumour immunity
- (2017) Sydney R. Gordon et al. NATURE
- COX2/mPGES1/PGE2pathway regulates PD-L1 expression in tumor-associated macrophages and myeloid-derived suppressor cells
- (2017) Victor Prima et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pyruvate Kinase M2 Is Required for the Expression of the Immune Checkpoint PD-L1 in Immune Cells and Tumors
- (2017) Eva M. Palsson-McDermott et al. Frontiers in Immunology
- An IL-27/Stat3 axis induces expression of programmed cell death 1 ligands (PD-L1/2) on infiltrating macrophages in lymphoma
- (2016) Hasita Horlad et al. CANCER SCIENCE
- Association of Pembrolizumab With Tumor Response and Survival Among Patients With Advanced Melanoma
- (2016) Antoni Ribas et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- CD47-blocking immunotherapies stimulate macrophage-mediated destruction of small-cell lung cancer
- (2016) Kipp Weiskopf et al. JOURNAL OF CLINICAL INVESTIGATION
- Durable antitumor responses to CD47 blockade require adaptive immune stimulation
- (2016) Jonathan T. Sockolosky et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- NF-κB Regulates PD-1 Expression in Macrophages
- (2015) Alexander P. R. Bally et al. JOURNAL OF IMMUNOLOGY
- Pembrolizumab for the Treatment of Non–Small-Cell Lung Cancer
- (2015) Edward B. Garon et al. NEW ENGLAND JOURNAL OF MEDICINE
- Human cancer immunotherapy with antibodies to the PD-1 and PD-L1 pathway
- (2015) Kim C. Ohaegbulam et al. TRENDS IN MOLECULAR MEDICINE
- Programmed Death 1 Deficiency Induces the Polarization of Macrophages/Microglia to the M1 Phenotype After Spinal Cord Injury in Mice
- (2014) Anhui Yao et al. Neurotherapeutics
- Gliomas Promote Immunosuppression through Induction of B7-H1 Expression in Tumor-Associated Macrophages
- (2013) O. Bloch et al. CLINICAL CANCER RESEARCH
- Chitin induces upregulation of B7-H1 on macrophages and inhibits T-cell proliferation
- (2010) Claudia J. Wagner et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- PD-1 negatively regulates interleukin-12 expression by limiting STAT-1 phosphorylation in monocytes/macrophages duringchronic hepatitis C virus infection
- (2010) Cheng J. Ma et al. IMMUNOLOGY
- Expression of PD-L1 and PD-L2 on human macrophages is up-regulated by HIV-1 and differentially modulated by IL-10
- (2010) M. Rodriguez-Garcia et al. JOURNAL OF LEUKOCYTE BIOLOGY
- PD-1 expression by macrophages plays a pathologic role in altering microbial clearance and the innate inflammatory response to sepsis
- (2009) X. Huang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Interferon-sensitive response element (ISRE) is mainly responsible for IFN-α-induced upregulation of programmed death-1 (PD-1) in macrophages
- (2008) Hae-Yun Cho et al. Biochimica et Biophysica Acta-Gene Regulatory Mechanisms
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