The genetic architecture of helminth-specific immune responses in a wild population of Soay sheep (Ovis aries)

Wild GWAS-association mapping in natural populations

(2018) Anna W. Santure et al.   Molecular Ecology Resources

CLEC16A regulates splenocyte and NK cell function in part through MEK signaling

(2018) Rahul Pandey et al.   PLoS One

Natural Selection on Antihelminth Antibodies in a Wild Mammal Population

(2018) Alexandra M. Sparks et al.   AMERICAN NATURALIST

Insights into the genetic architecture of morphological traits in two passerine bird species

(2017) C N S Silva et al.   HEREDITY

Estimating genetic and phenotypic parameters of cellular immune-associated traits in dairy cows

(2017) Scott J. Denholm et al.   JOURNAL OF DAIRY SCIENCE

Pedigree reconstruction from SNP data: parentage assignment, sibship clustering and beyond

(2017) Jisca Huisman   Molecular Ecology Resources

A tiling-deletion-based genetic screen for cis-regulatory element identification in mammalian cells

(2017) Yarui Diao et al.   NATURE METHODS

The comparative immunology of wild and laboratory mice, Mus musculus domesticus

(2017) Stephen Abolins et al.   Nature Communications

Conserved Genetic Architecture Underlying Individual Recombination Rate Variation in a Wild Population of Soay Sheep ( Ovis aries )

(2016) Susan E. Johnston et al.   GENETICS

Normalizing the environment recapitulates adult human immune traits in laboratory mice

(2016) Lalit K. Beura et al.   NATURE

Common variants at PVT1, ATG13–AMBRA1, AHI1 and CLEC16A are associated with selective IgA deficiency

(2016) Paola G Bronson et al.   NATURE GENETICS

The cellular composition of the human immune system is shaped by age and cohabitation

(2016) Edward J Carr et al.   NATURE IMMUNOLOGY

Shaping Variation in the Human Immune System

(2016) Adrian Liston et al.   TRENDS IN IMMUNOLOGY

Genomic Regions Associated with Sheep Resistance to Gastrointestinal Nematodes

(2016) Magda Vieira Benavides et al.   TRENDS IN PARASITOLOGY

Cellular and humoral immunity in a wild mammal: Variation with age & sex and association with overwinter survival

(2016) Rebecca L. Watson et al.   Ecology and Evolution

Conserved Genetic Architecture Underlying Individual Recombination Rate Variation in a Wild Population of Soay Sheep ( Ovis aries )

(2016) Susan E. Johnston et al.   GENETICS

The Genetic Architecture of the Human Immune System: A Bioresource for Autoimmunity and Disease Pathogenesis

(2015) Mario Roederer et al.   CELL

Variation in the Human Immune System Is Largely Driven by Non-Heritable Influences

(2015) Petter Brodin et al.   CELL

Genome-wide association and genome partitioning reveal novel genomic regions underlying variation in gastrointestinal nematode burden in a wild bird

(2015) Marius A. Wenzel et al.   MOLECULAR ECOLOGY

Heterogeneity of genetic architecture of body size traits in a free-living population

(2015) Camillo Bérénos et al.   MOLECULAR ECOLOGY

Replicated analysis of the genetic architecture of quantitative traits in two wild great tit populations

(2015) Anna W. Santure et al.   MOLECULAR ECOLOGY

Whole-genome resequencing of extreme phenotypes in collared flycatchers highlights the difficulty of detecting quantitative trait loci in natural populations

(2015) Marty Kardos et al.   Molecular Ecology Resources

Genome-wide association mapping in a wild avian population identifies a link between genetic and phenotypic variation in a life-history trait

(2015) A. Husby et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Evolution of the immune system in humans from infancy to old age

(2015) A. Katharina Simon et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Association of CLEC16A with human common variable immunodeficiency disorder and role in murine B cells

(2015) Jin Li et al.   Nature Communications

Multiple Sclerosis Risk Allele in CLEC16A Acts as an Expression Quantitative Trait Locus for CLEC16A and SOCS1 in CD4+ T Cells

(2015) Ingvild S. Leikfoss et al.   PLoS One

Heritable, Heterogeneous, and Costly Resistance of Sheep against Nematodes and Potential Feedbacks to Epidemiological Dynamics

(2014) Adam D. Hayward et al.   AMERICAN NATURALIST

High frequency of activated NKp46+natural killer cells in patients with new diagnosed of latent autoimmune diabetes in adults

(2014) Ye Wang et al.   AUTOIMMUNITY

Genetic and environmental variation in condition, cutaneous immunity, and haematocrit in house wrens

(2014) Scott K Sakaluk et al.   BMC EVOLUTIONARY BIOLOGY

A genome-wide association study of immune response traits in Canadian Holstein cattle

(2014) Kathleen A Thompson-Crispi et al.   BMC GENOMICS

Global Analyses of Human Immune Variation Reveal Baseline Predictors of Postvaccination Responses

(2014) John S. Tsang et al.   CELL

Natural selection on quantitative immune defence traits: a comparison between theory and data

(2014) O. Seppälä   JOURNAL OF EVOLUTIONARY BIOLOGY

Genome-wide SNP analysis reveals a genetic basis for sea-age variation in a wild population of Atlantic salmon (Salmo salar)

(2014) Susan E. Johnston et al.   MOLECULAR ECOLOGY

Estimating quantitative genetic parameters in wild populations: a comparison of pedigree and genomic approaches

(2014) Camillo Bérénos et al.   MOLECULAR ECOLOGY

Multivariate immune defences and fitness in the wild: complex but ecologically important associations among plasma antibodies, health and survival

(2014) D. H. Nussey et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

The sheep genome illuminates biology of the rumen and lipid metabolism

(2014) Y. Jiang et al.   SCIENCE

Genetic Variants Regulating Immune Cell Levels in Health and Disease

(2013) Valeria Orrù et al.   CELL

Multivariate heredity of melanin-based coloration, body mass and immunity

(2013) S-Y Kim et al.   HEREDITY

Genome-wide association and regional heritability mapping to identify loci underlying variation in nematode resistance and body weight in Scottish Blackface lambs

(2013) V Riggio et al.   HEREDITY

Introgression and the fate of domesticated genes in a wild mammal population

(2013) Philine G. D. Feulner et al.   MOLECULAR ECOLOGY

Life history trade-offs at a single locus maintain sexually selected genetic variation

(2013) Susan E. Johnston et al.   NATURE

Into the wild: digging at immunology's evolutionary roots

(2013) Rick M Maizels et al.   NATURE IMMUNOLOGY

From remote enhancers to gene regulation: charting the genome's regulatory landscapes

(2013) O. Symmons et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Identification of Immune Traits Correlated with Dairy Cow Health, Reproduction and Productivity

(2013) Georgios Banos et al.   PLoS One

Detecting genes for variation in parasite burden and immunological traits in a wild population: testing the candidate gene approach

(2012) E. A. Brown et al.   MOLECULAR ECOLOGY

Localising Loci underlying Complex Trait Variation Using Regional Genomic Relationship Mapping

(2012) Yoshitaka Nagamine et al.   PLoS One

Genome-Wide Analysis of the World's Sheep Breeds Reveals High Levels of Historic Mixture and Strong Recent Selection

(2012) James W. Kijas et al.   PLOS BIOLOGY

Genetic parameters of adaptive immune response traits in Canadian Holsteins

(2011) K.A. Thompson-Crispi et al.   JOURNAL OF DAIRY SCIENCE

Natural selection on a measure of parasite resistance varies across ages and environmental conditions in a wild mammal

(2011) A. D. HAYWARD et al.   JOURNAL OF EVOLUTIONARY BIOLOGY

Anti-CD180 (RP105) Activates B Cells To Rapidly Produce Polyclonal Ig via a T Cell and MyD88-Independent Pathway

(2011) Jay W. Chaplin et al.   JOURNAL OF IMMUNOLOGY

Wild immunology

(2011) AMY B. PEDERSEN et al.   MOLECULAR ECOLOGY

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

(2011) Stephen Sawcer et al.   NATURE

An inconvenient truth: Global worming and anthelmintic resistance

(2011) Ray M. Kaplan et al.   VETERINARY PARASITOLOGY

Genetic Diversity in Cytokines Associated with Immune Variation and Resistance to Multiple Pathogens in a Natural Rodent Population

(2011) Andrew K. Turner et al.   PLoS Genetics

GCTA: A Tool for Genome-wide Complex Trait Analysis

(2010) Jian Yang et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Consequences of immune system aging in nature: a study of immunosenescence costs in free-living Tree Swallows

(2010) Maria G. Palacios et al.   ECOLOGY

Sex-specific heritability of cell-mediated immune response in the blue tit nestlings (Cyanistes caeruleus)

(2010) S. M. DROBNIAK et al.   JOURNAL OF EVOLUTIONARY BIOLOGY

Association of IFIH1 and other autoimmunity risk alleles with selective IgA deficiency

(2010) Ricardo C Ferreira et al.   NATURE GENETICS

Genetic variation among lambs in peripheral IgE activity against the larval stages of Teladorsagia circumcincta

(2010) L. MURPHY et al.   PARASITOLOGY

Olfactomedin 4 down-regulates innate immunity against Helicobacter pylori infection

(2010) W. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fitness Correlates of Heritable Variation in Antibody Responsiveness in a Wild Mammal

(2010) Andrea L. Graham et al.   SCIENCE

Genetic parameters for resistance to trichostrongylid infection in dairy sheep

(2009) B. Gutiérrez-Gil et al.   Animal

A CLEC16A variant confers risk for juvenile idiopathic arthritis and anti-cyclic citrullinated peptide antibody negative rheumatoid arthritis

(2009) B. Skinningsrud et al.   ANNALS OF THE RHEUMATIC DISEASES

Mhc polymorphisms fail to explain the heritability of phytohaemagglutinin-induced skin swelling in a wild passerine

(2009) C. Bonneaud et al.   Biology Letters

Specific association of a CLEC16A/KIAA0350 polymorphism with NOD2/CARD15− Crohn's disease patients

(2009) Ana Márquez et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Identification of Novel Genes That Mediate Innate Immunity Using Inbred Mice

(2009) Ivana V. Yang et al.   GENETICS

Cross-fostering reveals sources of variation in innate immunity and hematocrit in nestling tree swallowsTachycineta bicolor

(2009) Erin S. Morrison et al.   JOURNAL OF AVIAN BIOLOGY

Mapping identifiers for the integration of genomic datasets with the R/Bioconductor package biomaRt

(2009) Steffen Durinck et al.   Nature Protocols

Teladorsagia circumcinctain the sheep abomasum: defining the role of dendritic cells in T cell regulation and protective immunity

(2009) T. N. MCNEILLY et al.   PARASITE IMMUNOLOGY

Pig peripheral blood mononuclear leucocyte subsets are heritable and genetically correlated with performance

(2008) M. Clapperton et al.   Animal

On multiple-testing correction in genome-wide association studies

(2008) Valentina Moskvina et al.   GENETIC EPIDEMIOLOGY

Polymorphisms inCLEC16AandCIITAat 16p13 Are Associated with Primary Adrenal Insufficiency

(2008) Beate Skinningsrud et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM