Transcriptional regulation in model organisms: recent progress and clinical implications

Regulatory principles governing the maternal-to-zygotic transition: insights from Drosophila melanogaster

(2019) Danielle C. Hamm et al.   Open Biology

Yeast Systems Biology: Model organism and Cell Factory

(2019) Jens Nielsen   Biotechnology Journal

A sleep-inducing gene, nemuri, links sleep and immune function in Drosophila

(2019) Hirofumi Toda et al.   SCIENCE

Linking immunity and sickness-induced sleep

(2019) Grigorios Oikonomou et al.   SCIENCE

Drosophila Histone Demethylase KDM5 Regulates Social Behavior through Immune Control and Gut Microbiota Maintenance

(2019) Kun Chen et al.   Cell Host & Microbe

Visualizing Engrafted Human Cancer and Therapy Responses in Immunodeficient Zebrafish

(2019) Chuan Yan et al.   CELL

The single-cell sequencing: new developments and medical applications

(2019) Xiaoning Tang et al.   Cell and Bioscience

Mitochondrial Translation Efficiency Controls Cytoplasmic Protein Homeostasis

(2018) Tamara Suhm et al.   Cell Metabolism

Ejaculation Induced by the Activation of Crz Neurons Is Rewarding to Drosophila Males

(2018) Shir Zer-Krispil et al.   CURRENT BIOLOGY

Molecular Mechanisms for CFIm-Mediated Regulation of mRNA Alternative Polyadenylation

(2018) Yong Zhu et al.   MOLECULAR CELL

mRNAs are sorted for export or degradation before passing through nuclear speckles

(2018) Jing Fan et al.   NUCLEIC ACIDS RESEARCH

Deficiency in class III PI3-kinase confers postnatal lethality with IBD-like features in zebrafish

(2018) Shaoyang Zhao et al.   Nature Communications

Functional Gut Microbiota Remodeling Contributes to the Caloric Restriction-Induced Metabolic Improvements

(2018) Salvatore Fabbiano et al.   Cell Metabolism

Chromosomal Instability Induces Cellular Invasion in Epithelial Tissues

(2018) Najate Benhra et al.   DEVELOPMENTAL CELL

Intronless mRNAs transit through nuclear speckles to gain export competence

(2018) Ke Wang et al.   JOURNAL OF CELL BIOLOGY

Transcriptional regulation of nitrogen-associated metabolism and growth

(2018) Allison Gaudinier et al.   NATURE

A gut microbial factor modulates locomotor behaviour in Drosophila

(2018) Catherine E. Schretter et al.   NATURE

Plant mitochondria synthesize melatonin and enhance the tolerance of plants to drought stress

(2017) Lin Wang et al.   JOURNAL OF PINEAL RESEARCH

Discovery of nitrate–CPK–NLP signalling in central nutrient–growth networks

(2017) Kun-hsiang Liu et al.   NATURE

Mono-unsaturated fatty acids link H3K4me3 modifiers to C. elegans lifespan

(2017) Shuo Han et al.   NATURE

Cis and trans determinants of epigenetic silencing by Polycomb repressive complex 2 in Arabidopsis

(2017) Jun Xiao et al.   NATURE GENETICS

ALYREF mainly binds to the 5′ and the 3′ regions of the mRNA in vivo

(2017) Min Shi et al.   NUCLEIC ACIDS RESEARCH

A Nucleus-Localized Long Non-Coding RNA Enhances Drought and Salt Stress Tolerance

(2017) Tao Qin et al.   PLANT PHYSIOLOGY

Transcription elongation rate has a tissue-specific impact on alternative cleavage and polyadenylation in Drosophila melanogaster

(2017) Xiaochuan Liu et al.   RNA

Host cell attachment elicits posttranscriptional regulation in infecting enteropathogenic bacteria

(2017) Naama Katsowich et al.   SCIENCE

The intestinal microbiota regulates body composition through NFIL3 and the circadian clock

(2017) Yuhao Wang et al.   SCIENCE

Driving mosquito refractoriness toPlasmodium falciparumwith engineered symbiotic bacteria

(2017) Sibao Wang et al.   SCIENCE

A conserved KLF-autophagy pathway modulates nematode lifespan and mammalian age-associated vascular dysfunction

(2017) Paishiun N. Hsieh et al.   Nature Communications

Polycomb repressive complex 1 modifies transcription of active genes

(2017) Michelle Pherson et al.   Science Advances

Transcriptional Responses to the Auxin Hormone

(2016) Dolf Weijers et al.   Annual Review of Plant Biology

Circadian Rhythm Disruption Promotes Lung Tumorigenesis

(2016) Thales Papagiannakopoulos et al.   Cell Metabolism

Alternative polyadenylation of mRNA precursors

(2016) Bin Tian et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Hobit and Blimp1 instruct a universal transcriptional program of tissue residency in lymphocytes

(2016) L. K. Mackay et al.   SCIENCE

Immune modulation by MANF promotes tissue repair and regenerative success in the retina

(2016) J. Neves et al.   SCIENCE

Evolution and Biological Roles of Alternative 3′UTRs

(2016) Christine Mayr   TRENDS IN CELL BIOLOGY

The Polycomb Group Protein Regulatory Network

(2015) Iva Mozgova et al.   Annual Review of Plant Biology

Xenograft models for normal and malignant stem cells

(2015) S. Goyama et al.   BLOOD

Global cancer statistics, 2012

(2015) Lindsey A. Torre et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Subcellular RNA profiling links splicing and nuclear DICER1 to alternative cleavage and polyadenylation

(2015) Jonathan Neve et al.   GENOME RESEARCH

Targeting Polycomb systems to regulate gene expression: modifications to a complex story

(2015) Neil P. Blackledge et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Branched-chain amino acid catabolism is a conserved regulator of physiological ageing

(2015) Johannes Mansfeld et al.   Nature Communications

Systematic Profiling of Poly(A)+ Transcripts Modulated by Core 3’ End Processing and Splicing Factors Reveals Regulatory Rules of Alternative Cleavage and Polyadenylation

(2015) Wencheng Li et al.   PLoS Genetics

Regeneration of the aged thymus by a single transcription factor

(2014) N. Bredenkamp et al.   DEVELOPMENT

CFIm25 links alternative polyadenylation to glioblastoma tumour suppression

(2014) Chioniso P. Masamha et al.   NATURE

Timing Mechanism Dependent on Cell Division Is Invoked by Polycomb Eviction in Plant Stem Cells

(2014) B. Sun et al.   SCIENCE

Cell Surface ABP1-TMK Auxin-Sensing Complex Activates ROP GTPase Signaling

(2014) T. Xu et al.   SCIENCE

Improving Microbial Biogasoline Production in Escherichia coli Using Tolerance Engineering

(2014) Jee Loon Foo et al.   mBio

A Genome-Scale Resource for the Functional Characterization of Arabidopsis Transcription Factors

(2014) Jose L. Pruneda-Paz et al.   Cell Reports

Landscape of transcription in human cells

(2012) Sarah Djebali et al.   NATURE

Foxn1 maintains thymic epithelial cells to support T-cell development via mcm2 in zebrafish

(2012) D. Ma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A neuropeptide circuit that coordinates sperm transfer and copulation duration in Drosophila

(2012) T. D. Tayler et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sexual Deprivation Increases Ethanol Intake in Drosophila

(2012) G. Shohat-Ophir et al.   SCIENCE

Genome-wide Analysis of Pre-mRNA 3′ End Processing Reveals a Decisive Role of Human Cleavage Factor I in the Regulation of 3′ UTR Length

(2012) Georges Martin et al.   Cell Reports

Definition and classification of cancer cachexia: an international consensus

(2011) Kenneth Fearon et al.   LANCET ONCOLOGY

Transcriptional Activators Enhance Polyadenylation of mRNA Precursors

(2011) Takashi Nagaike et al.   MOLECULAR CELL

A type III effector protease NleC from enteropathogenic Escherichia coli targets NF-κB for degradation

(2011) Jaclyn S. Pearson et al.   MOLECULAR MICROBIOLOGY

Transcriptional activity regulates alternative cleavage and polyadenylation

(2011) Z. Ji et al.   Molecular Systems Biology

Cell Surface- and Rho GTPase-Based Auxin Signaling Controls Cellular Interdigitation in Arabidopsis

(2010) Tongda Xu et al.   CELL

NleC, a Type III Secretion Protease, Compromises NF-κB Activation by Targeting p65/RelA

(2010) Hilo Yen et al.   PLoS Pathogens

Enterohaemorrhagic Escherichia coli serogroup O111 inhibits NF- B-dependent innate responses in a manner independent of a type III secreted OspG orthologue

(2009) R. Nobe et al.   MICROBIOLOGY-SGM

Mammalian pre-mRNA 3′ End Processing Factor CF Im68 Functions in mRNA Export

(2009) Marc-David Ruepp et al.   MOLECULAR BIOLOGY OF THE CELL

The nodule inception-like protein 7 modulates nitrate sensing and metabolism in Arabidopsis

(2008) Loren Castaings et al.   PLANT JOURNAL