Behavioral analysis in mice deficient for GAREM2 (Grb2-associated regulator of Erk/MAPK subtype2) that is a subtype of highly expressing in the brain

The dynamic and stress-adaptive signaling hub of 14-3-3: emerging mechanisms of regulation and context-dependent protein–protein interactions

(2018) KL Pennington et al.   ONCOGENE

Behavioral and neuroanatomical analyses in a genetic mouse model of 2q13 duplication

(2017) Keiko Kishimoto et al.   GENES TO CELLS

Intersectin 1 is a component of the Reelin pathway to regulate neuronal migration and synaptic plasticity in the hippocampus

(2017) Burkhard Jakob et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Comprehensive pancancer genomic analysis reveals (RTK)-RAS-RAF-MEK as a key dysregulated pathway in cancer: Its clinical implications

(2017) Robin Imperial et al.   SEMINARS IN CANCER BIOLOGY

The Dark Side of Cell Signaling: Positive Roles for Negative Regulators

(2016) Mark A. Lemmon et al.   CELL

Reduced Anxiety-Like Behavior and Altered Hippocampal Morphology in Female p75NTRexon IV−/− Mice

(2016) Zoe Puschban et al.   Frontiers in Behavioral Neuroscience

Functional relationship between CABIT, SAM and 14-3-3 binding domains of GAREM1 that play a role in its subcellular localization

(2015) Tasuku Nishino et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Targeting Signaling Transduction Pathways in Bladder Cancer

(2015) Phillip H. Abbosh et al.   Current Oncology Reports

Targeting SH2 domains in breast cancer

(2014) Pietro Morlacchi et al.   Future Medicinal Chemistry

SHP-2 Regulates Growth Factor Dependent Vascular Signalling and Function

(2014) Hanna Mannell et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Common dysregulation network in the human prefrontal cortex underlies two neurodegenerative diseases

(2014) M. Narayanan et al.   Molecular Systems Biology

A Brain-specific Grb2-associated Regulator of Extracellular Signal-regulated Kinase (Erk)/Mitogen-activated Protein Kinase (MAPK) (GAREM) Subtype, GAREM2, Contributes to Neurite Outgrowth of Neuroblastoma Cells by Regulating Erk Signaling

(2013) Tomonori Taniguchi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Vertebrate Intersectin1 Is Repurposed to Facilitate Cortical Midline Connectivity and Higher Order Cognition

(2013) A. S. Sengar et al.   JOURNAL OF NEUROSCIENCE

Impairments in Neurogenesis Are Not Tightly Linked to Depressive Behavior in a Transgenic Mouse Model of Alzheimer's Disease

(2013) Daniel M. Iascone et al.   PLoS One

EGF receptor trafficking: consequences for signaling and cancer

(2013) Alejandra Tomas et al.   TRENDS IN CELL BIOLOGY

GAB2--a Scaffolding Protein in Cancer

(2012) S. J. Adams et al.   MOLECULAR CANCER RESEARCH

Intersectin (ITSN) Family of Scaffolds Function as Molecular Hubs in Protein Interaction Networks

(2012) Katy A. Wong et al.   PLoS One

MAPK Signaling Determines Anxiety in the Juvenile Mouse Brain but Depression-Like Behavior in Adults

(2012) Benedikt Wefers et al.   PLoS One

The insulin receptor substrate (IRS) proteins

(2011) Leslie M. Shaw   CELL CYCLE

ERK2 Contributes to the Control of Social Behaviors in Mice

(2011) Y. Satoh et al.   JOURNAL OF NEUROSCIENCE

Order and disorder in large multi-site docking proteins of the Gab family—implications for signalling complex formation and inhibitor design strategies

(2011) Philip C. Simister et al.   Molecular BioSystems

Post-translational modification of 14-3-3 isoforms and regulation of cellular function

(2011) Alastair Aitken   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Cell Signaling by Receptor Tyrosine Kinases

(2010) Mark A. Lemmon et al.   CELL

Decreased Exploratory Activity in a Mouse Model of 15q Duplication Syndrome; Implications for Disturbance of Serotonin Signaling

(2010) Kota Tamada et al.   PLoS One

Anti-depressant and anxiolytic like behaviors in PKCI/HINT1 knockout mice associated with elevated plasma corticosterone level

(2009) Elisabeth Barbier et al.   BMC NEUROSCIENCE

GAREM, a Novel Adaptor Protein for Growth Factor Receptor-bound Protein 2, Contributes to Cellular Transformation through the Activation of Extracellular Signal-regulated Kinase Signaling

(2009) Kyoko Tashiro et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Abnormal social behavior, hyperactivity, impaired remote spatial memory, and increased D1-mediated dopaminergic signaling in neuronal nitric oxide synthase knockout mice

(2009) Koichi Tanda et al.   Molecular Brain