Targeting the JAK/STAT Pathway in T Cell Lymphoproliferative Disorders
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Title
Targeting the JAK/STAT Pathway in T Cell Lymphoproliferative Disorders
Authors
Keywords
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Journal
Current Hematologic Malignancy Reports
Volume -, Issue -, Pages -
Publisher
Springer Science and Business Media LLC
Online
2019-11-18
DOI
10.1007/s11899-019-00545-5
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Note: Only part of the references are listed.- ECPIRM, a Potential Therapeutic Agent for Cutaneous T-Cell Lymphoma, Inhibits Cell Proliferation and Promotes Apoptosis via a JAK/STAT Pathway
- (2018) Hua Yang et al. Anti-Cancer Agents in Medicinal Chemistry
- The 2017 WHO update on mature T- and natural killer (NK) cell neoplasms
- (2018) E. Matutes International Journal of Laboratory Hematology
- The Genomics and Molecular Biology of Natural Killer/T-Cell Lymphoma: Opportunities for Translation
- (2018) Sanjay de Mel et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Oncogenic activation of JAK3-STAT signaling confers clinical sensitivity to PRN371, a novel selective and potent JAK3 inhibitor, in natural killer/T-cell lymphoma
- (2018) M. -L. Nairismägi et al. LEUKEMIA
- Molecular advances in cutaneous T-cell lymphoma
- (2018) Armando N. Bastidas Torres et al. SEMINARS IN CUTANEOUS MEDICINE AND SURGERY
- Aggressive natural killer-cell leukemia mutational landscape and drug profiling highlight JAK-STAT signaling as therapeutic target
- (2018) Olli Dufva et al. Nature Communications
- Inhibiting Janus Kinase 1 and BCL-2 to treat T cell acute lymphoblastic leukemia with IL7-Rα mutations
- (2018) Emilee Senkevitch et al. Oncotarget
- STAT5 inhibition induces TRAIL/DR4 dependent apoptosis in peripheral T-cell lymphoma
- (2018) Haley M. Simpson et al. Oncotarget
- Oncogenic activation of the STAT3 pathway drives PD-L1 expression in natural killer/T-cell lymphoma
- (2018) Tammy Linlin Song et al. BLOOD
- Frequent Mutations in Natural Killer/T Cell Lymphoma
- (2018) Yanjie Zhang et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Frequent activating STAT3 mutations and novel recurrent genomic abnormalities detected in breast implant-associated anaplastic large cell lymphoma
- (2018) Piers Blombery et al. Oncotarget
- JAK/STAT pathway inhibition overcomes IL7-induced glucocorticoid resistance in a subset of human T-cell acute lymphoblastic leukemias
- (2017) C Delgado-Martin et al. LEUKEMIA
- JAK/STAT pathway directed therapy of T-cell leukemia/lymphoma: Inspired by functional and structural genomics
- (2017) Thomas A. Waldmann MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Jak Stat signaling and cancer: Opportunities, benefits and side effects of targeted inhibition
- (2017) Bernd Groner et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- The Genetic Basis of Hepatosplenic T-cell Lymphoma
- (2017) Matthew McKinney et al. Cancer Discovery
- The effect of the JAK2 inhibitor TG101209 against T cell acute lymphoblastic leukemia (T-ALL) is mediated by inhibition of JAK-STAT signaling and activation of the crosstalk between apoptosis and autophagy signaling
- (2017) Zhao Cheng et al. Oncotarget
- JAK-STAT signaling in cancer: From cytokines to non-coding genome
- (2016) Jan Pencik et al. CYTOKINE
- FrequentBCORaberrations in extranodal NK/T-Cell lymphoma, nasal type
- (2016) Akito Dobashi et al. GENES CHROMOSOMES & CANCER
- The JAK-STAT Pathway: Impact on Human Disease and Therapeutic Intervention
- (2015) John J. O'Shea et al. Annual Review of Medicine
- Receptor-type tyrosine-protein phosphatase directly targets STAT3 activation for tumor suppression in nasal NK/T-cell lymphoma
- (2015) Y.-W. Chen et al. BLOOD
- Whole-genome sequencing reveals oncogenic mutations in mycosis fungoides
- (2015) L. Y. McGirt et al. BLOOD
- Convergent Mutations and Kinase Fusions Lead to Oncogenic STAT3 Activation in Anaplastic Large Cell Lymphoma
- (2015) Ramona Crescenzo et al. CANCER CELL
- JAK kinase targeting in hematologic malignancies: a sinuous pathway from identification of genetic alterations towards clinical indications
- (2015) L. Springuel et al. HAEMATOLOGICA
- Exome sequencing identifies somatic mutations of DDX3X in natural killer/T-cell lymphoma
- (2015) Lu Jiang et al. NATURE GENETICS
- The mutational landscape of cutaneous T cell lymphoma and Sézary syndrome
- (2015) Ana Carolina da Silva Almeida et al. NATURE GENETICS
- Selective targeting of JAK/STAT signaling is potentiated by Bcl-xL blockade in IL-2–dependent adult T-cell leukemia
- (2015) Meili Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Activating mutations of STAT5B and STAT3 in lymphomas derived from γδ-T or NK cells
- (2015) Can Küçük et al. Nature Communications
- Genetic alterations of JAK/STAT cascade and histone modification in extranodal NK/T-cell lymphoma nasal type
- (2015) Seungbok Lee et al. Oncotarget
- JAK kinase targeting in hematologic malignancies: a sinuous pathway from identification of genetic alterations towards clinical indications
- (2015) L. Springuel et al. HAEMATOLOGICA
- STAT5b in LGL leukemia – a novel therapeutic target?
- (2015) Hanna L. M. Rajala et al. Oncotarget
- Integrated genomic sequencing reveals mutational landscape of T-cell prolymphocytic leukemia
- (2014) M. J. Kiel et al. BLOOD
- Recurrent mutation ofJAK3in T-cell prolymphocytic leukemia
- (2014) Anke K. Bergmann et al. GENES CHROMOSOMES & CANCER
- Frequent STAT5B mutations in γδ hepatosplenic T-cell lymphomas
- (2014) A Nicolae et al. LEUKEMIA
- A targeted mutational landscape of angioimmunoblastic T-cell lymphoma
- (2013) O. Odejide et al. BLOOD
- Discovery of somatic STAT5b mutations in large granular lymphocytic leukemia
- (2013) H. L. M. Rajala et al. BLOOD
- Recurrent JAK1 and JAK3 somatic mutations in T-cell prolymphocytic leukemia
- (2013) D Bellanger et al. LEUKEMIA
- JAK3 deregulation by activating mutations confers invasive growth advantage in extranodal nasal-type natural killer cell lymphoma
- (2013) A Bouchekioua et al. LEUKEMIA
- STAT3 mutations are frequent in CD30+ T-cell lymphomas and T-cell large granular lymphocytic leukemia
- (2013) R S Ohgami et al. LEUKEMIA
- Rare occurrence ofJAK3mutations in natural killer cell neoplasms in Japan
- (2013) Hiroshi Kimura et al. LEUKEMIA & LYMPHOMA
- TYK2–STAT1–BCL2 Pathway Dependence in T-cell Acute Lymphoblastic Leukemia
- (2013) Takaomi Sanda et al. Cancer Discovery
- STAT3 mutations unify the pathogenesis of chronic lymphoproliferative disorders of NK cells and T-cell large granular lymphocyte leukemia
- (2012) A. Jerez et al. BLOOD
- Mutation of the receptor tyrosine phosphatase PTPRC (CD45) in T-cell acute lymphoblastic leukemia
- (2012) M. Porcu et al. BLOOD
- Genetic Alterations Activating Kinase and Cytokine Receptor Signaling in High-Risk Acute Lymphoblastic Leukemia
- (2012) Kathryn G. Roberts et al. CANCER CELL
- Newly described activating JAK3 mutations in T-cell acute lymphoblastic leukemia
- (2012) T Bains et al. LEUKEMIA
- The genetic basis of early T-cell precursor acute lymphoblastic leukaemia
- (2012) Jinghui Zhang et al. NATURE
- SomaticSTAT3Mutations in Large Granular Lymphocytic Leukemia
- (2012) Hanna L.M. Koskela et al. NEW ENGLAND JOURNAL OF MEDICINE
- Janus Kinase 3–Activating Mutations Identified in Natural Killer/T-cell Lymphoma
- (2012) Ghee Chong Koo et al. Cancer Discovery
- PTPN2 negatively regulates oncogenic JAK1 in T-cell acute lymphoblastic leukemia
- (2011) M. Kleppe et al. BLOOD
- Gain-of-function mutations ininterleukin-7 receptor-α(IL7R) in childhood acute lymphoblastic leukemias
- (2011) Chen Shochat et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Oncogenic IL7R gain-of-function mutations in childhood T-cell acute lymphoblastic leukemia
- (2011) Priscila P Zenatti et al. NATURE GENETICS
- Deletion of the protein tyrosine phosphatase gene PTPN2 in T-cell acute lymphoblastic leukemia
- (2010) Maria Kleppe et al. NATURE GENETICS
- Somatic Mutations of JAK1 and JAK3 in Acute Leukemias and Solid Cancers
- (2008) E. G. Jeong et al. CLINICAL CANCER RESEARCH
- Somatically acquiredJAK1mutations in adult acute lymphoblastic leukemia
- (2008) Elisabetta Flex et al. JOURNAL OF EXPERIMENTAL MEDICINE
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