Article
Nutrition & Dietetics
Ban-Hock Khor, Dina A. Tallman, Tilakavati Karupaiah, Pramod Khosla, Maria Chan, Joel D. Kopple
Summary: This study evaluated the nutrient composition of plant-based low protein diets and moderately high protein diets for chronic kidney disease patients in the Asia Pacific region. The study found that plant-based diets were deficient in essential amino acids at lower protein prescriptions, but met the Recommended Dietary Allowances at higher protein intakes. Plant-based and vegetarian diets contained higher potassium, phosphorus, and calcium content but lower long-chain n-3 polyunsaturated fatty acids and vitamin B-12 compared to conventional diets. Planning of all low protein diets, especially plant-based and vegetarian diets, should ensure the adequacy of all nutrients, particularly essential amino acids, and consider supplementing with multivitamins and trace elements.
Review
Nutrition & Dietetics
Annalisa Noce, Giulia Marrone, Georgia Wilson Jones, Manuela Di Lauro, Anna Pietroboni Zaitseva, Linda Ramadori, Roberto Celotto, Anna Paola Mitterhofer, Nicola Di Daniele
Summary: Metabolic acidosis is a severe complication of chronic kidney disease, and dietary-nutritional treatments can effectively control it, with different dietary regimens having their own advantages and limitations.
Review
Nutrition & Dietetics
Yusuke Sakaguchi, Jun-Ya Kaimori, Yoshitaka Isaka
Summary: Dietary protein restriction has long been practiced in the nutritional therapy of chronic kidney diseases (CKD), but the recommended amounts vary across guidelines due to conflicting results from previous trials. Recent studies have shown that a vegetarian, very low protein diet can reduce the risk of kidney failure among advanced CKD patients without increasing hyperkalemia. Plant-dominant low-protein diets (PLADO) are proposed as an alternative therapy for CKD patients, offering several potential benefits such as reducing toxin production, correcting metabolic imbalances, and preventing vascular calcification. However, further evidence is needed to establish the efficacy, safety, and feasibility of PLADO in real-world CKD patients.
Review
Nutrition & Dietetics
John S. Babich, Kamyar Kalantar-Zadeh, Shivam Joshi
Summary: Traditionally, diets for kidney disease restricted potassium intake from plant foods, but current evidence shows that this restriction is unnecessary. The correlation between dietary potassium and serum potassium is not significant, likely due to the effects of fiber, alkalinizing properties of fruits and vegetables, and the bioavailability of dietary potassium in plant foods. Consumption of plant foods may have multiple benefits for patients with CKD. Therefore, emerging dietary recommendations for kidney health should not restrict potassium intake from plant foods.
JOURNAL OF RENAL NUTRITION
(2022)
Review
Nutrition & Dietetics
Micaela Costacurta, Michele Basilicata, Giulia Marrone, Manuela Di Lauro, Vincenzo Campolattano, Patrizio Bollero, Raffaella Docimo, Nicola Di Daniele, Annalisa Noce
Summary: Several studies have shown a strong link between periodontal diseases and chronic kidney disease, possibly due to malnutrition, vitamin dysregulation, oxidative stress, metabolic acidosis, and low-grade inflammation. It is important for a multidisciplinary team to manage patients with these two conditions and develop treatment strategies.
Review
Nutrition & Dietetics
Paulina Mertowska, Sebastian Mertowski, Julia Wojnicka, Izabela Korona-Glowniak, Ewelina Grywalska, Anna Blazewicz, Wojciech Zaluska
Summary: Chronic kidney disease is a progressive and irreversible condition that can lead to alterations in the gut microbiota and activation of the immune system, with dietary factors playing a significant role in immune cell activation and microbiota balance. Understanding the relationship between intestinal microbiota and kidney dysfunction is crucial in the progression of kidney diseases.
Article
Nutrition & Dietetics
Almudena Perez-Torres, M. Elena Gonzalez Garcia, Marta Ossorio-Gonzalez, Laura Alvarez Garcia, M. Auxiliadora Bajo, Gloria del Peso, Ana Castillo Plaza, Rafael Selgas
Summary: Individualized nutrition education for patients with end-stage kidney disease has long-term positive effects on nutritional status, reducing hospitalizations, and increasing survival rates. Patients who did not receive nutritional interventions had higher mortality odds ratio.
Article
Nutrition & Dietetics
Yu-Jin Kwon, Kyongmin Park, Jun-Hyuk Lee
Summary: Protein intake, especially plant proteins, was negatively associated with the incidence of new-onset CKD in middle-aged and older Korean adults.
EUROPEAN JOURNAL OF NUTRITION
(2022)
Article
Multidisciplinary Sciences
Yuya Yoshida, Naoya Matsunaga, Takaharu Nakao, Kengo Hamamura, Hideaki Kondo, Tomomi Ide, Hiroyuki Tsutsui, Akito Tsuruta, Masayuki Kurogi, Michio Nakaya, Hitoshi Kurose, Satoru Koyanagi, Shigehiro Ohdo
Summary: Dysfunction of the circadian clock is linked to cardiovascular disease pathogenesis. Even in the presence of high blood pressure and elevated levels of angiotensin II, Clk/Clk mice with chronic kidney disease show reduced cardiac inflammation and fibrosis. The monocytic expression of GPR68, induced by altered CLOCK activation, exacerbates heart inflammation and fibrosis under CKD conditions.
NATURE COMMUNICATIONS
(2021)
Review
Nutrition & Dietetics
Kelly Picard, Diana R. Mager, Caroline Richard
Summary: Evidence suggests that higher plant-protein intake is associated with lower serum phosphate levels in adults with CKD, although not consistently significant. Increasing the proportion of plant protein in the diet may lead to lower phosphorus intake but equivalent serum phosphate concentrations. The relationship between plant protein intake and serum phosphate concentrations is not clear-cut, and longer intervention trials with larger sample sizes are needed for further evaluation.
ADVANCES IN NUTRITION
(2021)
Review
Nutrition & Dietetics
Marta Potrykus, Sylwia Czaja-Stolc, Sylwia Malgorzewicz, Monika Proczko-Stepaniak, Alicja Debska-Slizien
Summary: Morbid obesity is a prevalent disease in the 21st century, contributing to increased mortality and decreased life expectancy. It is associated with various metabolic abnormalities and is particularly prevalent among patients with chronic kidney disease (CKD). The management of obesity in CKD patients presents unique challenges due to the concomitant disorders and complications associated with impaired kidney function. This study aims to analyze the bariatric treatment of obesity in CKD patients and compare the recommendations in bariatrics and CKD management.
Article
Nutrition & Dietetics
Sofia Cecchi, Silvio Di Stante, Sara Belcastro, Veronica Bertuzzi, Assunta Cardillo, Laura Diotallevi, Xhensila Grabocka, Hrissa Kulurianu, Mauro Martello, Valentina Nastasi, Osmy Paci Della Costanza, Francesca Pizzolante, Marina Di Luca
Summary: Supplemented very low-protein diet (sVLPD) has been effective in delaying the start of dialysis treatment for stage 5 chronic renal failure patients, but it may increase the risk of malnutrition and is difficult to implement. By prescribing sVLPD supplemented with essential amino acids instead of keto-analogues, the progression of chronic kidney disease was slowed down and the start of dialysis treatment was delayed without evidence of malnutrition.
Review
Nutrition & Dietetics
Tania Naber, Sharad Purohit
Summary: Chronic kidney disease affects millions of adults in the US, interfering with the body's physiological mechanisms. Monitoring protein and other nutrients can slow disease progression, while plant-based diets show potential benefits and medical nutrition therapy is crucial in CKD intervention.
Review
Nutrition & Dietetics
Carolina Constantin, Mihaela Surcel, Adriana Munteanu, Monica Neagu, Jean Christopher Chamcheu
Summary: Psoriasis, an autoimmune chronic inflammatory skin condition, is influenced by genetic factors, immune disturbances, and environmental factors, especially the Western lifestyle and overall diet. Obesity is identified as a significant risk factor for psoriasis, aggravating the disease, while weight reduction can improve clinical outcomes. The connection between obesity and psoriasis lies in the pro-inflammatory effects of white adipose tissue, which is an important endocrine organ. This paper emphasizes the importance of nutrition strategies in psoriasis management.
Review
Geriatrics & Gerontology
B. Abiri, F. Hosseinpanah, Z. Seifi, S. Amini, Majid Valizadeh
Summary: This systematic review examines the potential dietary factors that may contribute to the development of sarcopenic obesity in the elderly population. The study found that appropriate intake of calories, macronutrients, micronutrients, antioxidant nutrients, vegetables, fruits, and overall dietary quality have been shown to be effective in preventing and treating sarcopenic obesity. A combination of hypocaloric diet and high protein intake may be necessary for managing both obesity and sarcopenia in older individuals.
JOURNAL OF NUTRITION HEALTH & AGING
(2023)
Article
Endocrinology & Metabolism
Holly Kramer, Robert E. Boucher, David Leehey, Linda Fried, Guo Wei, Tom Greene, Sylvia E. Rosas, Richard Cooper, Guichan Cao, Srinivasan Beddhu
Article
Urology & Nephrology
Talar W. Markossian, Holly J. Kramer, Nicholas J. Burge, Ivan V. Pacold, David J. Leehey, Zhiping Huo, Julia Schneider, Benjamin Ling, Kevin T. Stroupe
HEMODIALYSIS INTERNATIONAL
(2019)
Editorial Material
Transplantation
Kamyar Kalantar-Zadeh, Holly M. Kramer, Denis Fouque
NEPHROLOGY DIALYSIS TRANSPLANTATION
(2020)
Article
Obstetrics & Gynecology
Aelia Akbar, Kiang Liu, Erin D. Michos, Linda Brubaker, Talar Markossian, Michael P. Bancks, Holly Kramer
Summary: The study found that the prevalence of stress urinary incontinence and mixed urinary incontinence was significantly lower among black women compared to white women, but no significant differences were noted for Chinese or Hispanic women. There were no racial and ethnic differences in urgency urinary incontinence prevalence after adjusting for covariates. Most women with urinary incontinence reported significant bother regardless of race and ethnicity and urinary incontinence subtype.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Gautam R. Shroff, Otto A. Sanchez, Michael D. Miedema, Holly Kramer, Joachim H. Ix, Daniel A. Duprez, David R. Jacobs
Article
Peripheral Vascular Disease
Aelia Akbar, Kiang Liu, Erin D. Michos, Michael P. Bancks, Linda Brubaker, Talar Markossian, Ramon Durazo-Arvizu, Holly Kramer
Summary: The study found that overactive bladder (OAB) may lead to higher blood pressure and have negative effects on blood pressure control in men.
AMERICAN JOURNAL OF HYPERTENSION
(2022)
Article
Peripheral Vascular Disease
Leo Gozdecki, Holly Kramer, Matthew Thomas, Karam Gardezi, Elizabeth Tarlov, Ashley Hughes, Kevin Stroupe, Meghan O'Halloran
Summary: This 20-week quality improvement study examines the implementation of a hypertension identification and management program using a standardized oscillometric blood pressure measurement protocol. The study found that the implementation of the protocol reduced digit preference and improved hypertension treatment.
JOURNAL OF HUMAN HYPERTENSION
(2023)
Editorial Material
Urology & Nephrology
Emily Janak, Holly Kramer
CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Yuni Choi, David R. Jacobs, Gautam R. Shroff, Holly Kramer, Alexander R. Chang, Daniel A. Duprez
Summary: This study found that progression to higher CKD risk categories was common among young to middle-aged adults, and it was associated with cardiovascular disease and mortality.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2022)
Article
Peripheral Vascular Disease
Meghan O'Halloran, Ashley M. Hughes, Zhiping Huo, Frances Weaver, Kevin Stroupe, Elizabeth Tarlov, Holly Kramer
Summary: This study examines the accuracy of blood pressure measurement in Veterans Affairs (VA) medical centers and the perceptions of clinicians regarding blood pressure measurement. The results show that terminal digit preference (TDP) exists in VA medical centers, indicating a bias in BP measurement. The study also finds that the level of TDP varies among different centers and is associated with higher blood pressure control rates. Clinicians reported using semi-automated oscillometric devices for BP measurement, but still relied on auscultatory methods for confirmation. This highlights the importance of addressing TDP and improving the accuracy of BP measurement in VA medical centers.
JOURNAL OF CLINICAL HYPERTENSION
(2023)
Article
Health Care Sciences & Services
Talar W. Markossian, Jason Boyda, Jennifer Taylor, Bella Etingen, Francois Modave, Ron Price, Holly J. Kramer
Summary: Chronic kidney disease (CKD) is a common and costly condition that can be better managed through the use of mobile apps to enhance patient self-management, which in turn can improve overall management of CKD.
JMIR HUMAN FACTORS
(2021)
Article
Urology & Nephrology
Nicolas Krepostman, Holly Kramer
Article
Urology & Nephrology
Tara Chang, Guo Wei, Robert Boucher, Holly Kramer, Glenn M. Chertow, Alfred K. Cheung, Tom Greene, Paul K. Whelton, Srinivasan Beddhu
Article
Urology & Nephrology
Talar W. Markossian, Holly J. Kramer, Nicholas J. Burge, Ivan V. Pacold, David J. Leehey, Zhiping Huo, Julia Schneider, Benjamin Ling, Kevin T. Stroupe
CLINICAL KIDNEY JOURNAL
(2019)
Review
Nutrition & Dietetics
Chong-Su Kim
Summary: The gut microbiota plays a crucial role in brain function through the gut-brain axis. This review highlights the effects of gut microbiota-derived dietary metabolites on cell-to-cell interactions in the central nervous system, particularly microglia, astrocytes, and neuronal cells, affecting cognitive function, mood, and behavior. The review also discusses the potential of diet-induced microbial metabolite-based therapies as novel approaches to mental health treatment.
ADVANCES IN NUTRITION
(2024)