PLGA Porous Microspheres Dry Powders for Codelivery of Afatinib‐Loaded Solid Lipid Nanoparticles and Paclitaxel: Novel Therapy for EGFR Tyrosine Kinase Inhibitors Resistant Nonsmall Cell Lung Cancer

Cancer statistics, 2019

(2019) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Nilotinib Alters the Efflux Transporter-Mediated Pharmacokinetics of Afatinib in Mice

(2019) Ronilda R. D’Cunha et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Anhydrous reverse micelle lecithin nanoparticles/PLGA composite microspheres for long-term protein delivery with reduced initial burst

(2018) Longkai Chen et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Determination of tyrosine kinase inhibitor afatinib in rat plasma using LC–MS/MS and its application to in vivo pharmacokinetic studies of afatinib liposomes

(2018) Xiaoyan Lu et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Development of levofloxacin-loaded PLGA microspheres of suitable properties for sustained pulmonary release

(2018) Marisa C. Gaspar et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Exploring polyvinylpyrrolidone in the engineering of large porous PLGA microparticles via single emulsion method with tunable sustained release in the lung: In vitro and in vivo characterization

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Co-activation of STAT3 and YES-Associated Protein 1 (YAP1) Pathway in EGFR-Mutant NSCLC

(2017) Imane Chaib et al.   JNCI-Journal of the National Cancer Institute

Functionalizing PLGA and PLGA Derivatives for Drug Delivery and Tissue Regeneration Applications

(2017) Cláudia Martins et al.   Advanced Healthcare Materials

Toward a Single-Dose Vaccination Strategy with Self-Encapsulating PLGA Microspheres

(2017) Brittany A. Bailey et al.   Advanced Healthcare Materials

Co-activation of STAT3 and YES-Associated Protein 1 (YAP1) Pathway in EGFR-Mutant NSCLC

(2017) Imane Chaib et al.   JNCI-Journal of the National Cancer Institute

Tricolor R/G/B Laser Diode Based Eye-Safe White Lighting Communication Beyond 8 Gbit/s

(2017) Tsai-Chen Wu et al.   Scientific Reports

Characterization and release kinetics of liposomes inserted by pH-responsive bola-polymer

(2016) Weiju Hao et al.   COLLOID AND POLYMER SCIENCE

Afatinib-based combination regimens for the treatment of solid tumors: rationale, emerging strategies and recent progress

(2016) Jaafar Bennouna et al.   Future Oncology

Understanding Mechanisms of Resistance in the Epithelial Growth Factor Receptor in Non‐Small Cell Lung Cancer and the Role of Biopsy at Progression

(2016) Mark A. Socinski et al.   ONCOLOGIST

Afatinib beyond progression in patients with non-small-cell lung cancer following chemotherapy, erlotinib/gefitinib and afatinib: phase III randomized LUX-Lung 5 trial

(2015) M. Schuler et al.   ANNALS OF ONCOLOGY

AZD9291, an Irreversible EGFR TKI, Overcomes T790M-Mediated Resistance to EGFR Inhibitors in Lung Cancer

(2014) D. A. E. Cross et al.   Cancer Discovery

Analysis of Tumor Specimens at the Time of Acquired Resistance to EGFR-TKI Therapy in 155 Patients with EGFR-Mutant Lung Cancers

(2013) H. A. Yu et al.   CLINICAL CANCER RESEARCH

Alternative carriers in dry powder inhaler formulations

(2013) Yahya Rahimpour et al.   DRUG DISCOVERY TODAY

Validation of a General In Vitro Approach for Prediction of Total Lung Deposition in Healthy Adults for Pharmaceutical Inhalation Products

(2013) Bo Olsson et al.   Journal of Aerosol Medicine and Pulmonary Drug Delivery

Modeling of drug release from delivery systems based on hydroxypropyl methylcellulose (HPMC)

(2012) J. Siepmann et al.   ADVANCED DRUG DELIVERY REVIEWS

Biodegradation and biocompatibility of PLA and PLGA microspheres

(2012) James M. Anderson et al.   ADVANCED DRUG DELIVERY REVIEWS

Doxorubicin-loaded highly porous large PLGA microparticles as a sustained- release inhalation system for the treatment of metastatic lung cancer

(2012) Insoo Kim et al.   BIOMATERIALS

Building and maintaining the epithelium of the lung

(2012) Craig R. Rackley et al.   JOURNAL OF CLINICAL INVESTIGATION

Afatinib pharmacokinetics and metabolism after oral administration to healthy male volunteers

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The Tumor Lysis Syndrome

(2011) Scott C. Howard et al.   NEW ENGLAND JOURNAL OF MEDICINE

PLGA Microparticles Encapsulating Prostaglandin E1-Hydroxypropyl-β-cyclodextrin (PGE1-HPβCD) Complex for the Treatment of Pulmonary Arterial Hypertension (PAH)

(2011) Vivek Gupta et al.   PHARMACEUTICAL RESEARCH

Recommendations for the evaluation of risk and prophylaxis of tumour lysis syndrome (TLS) in adults and children with malignant diseases: an expert TLS panel consensus

(2010) Mitchell S. Cairo et al.   BRITISH JOURNAL OF HAEMATOLOGY

Preparation of budesonide-loaded porous PLGA microparticles and their therapeutic efficacy in a murine asthma model

(2010) Yu Jin Oh et al.   JOURNAL OF CONTROLLED RELEASE

Choosing inhaler devices for people with asthma: Current knowledge and outstanding research needs

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Development of highly porous large PLGA microparticles for pulmonary drug delivery

(2009) Yan Yang et al.   BIOMATERIALS

Development of a standardized dissolution test method for inhaled pharmaceutical formulations

(2009) Yoen-Ju Son et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Short- and long-term stability study of lyophilized solid lipid nanoparticles for gene therapy

(2008) A. del Pozo-Rodríguez et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Principles of encapsulating hydrophobic drugs in PLA/PLGA microparticles

(2008) Christian Wischke et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Insulin-loaded PLGA/cyclodextrin large porous particles with improved aerosolization properties: In vivo deposition and hypoglycaemic activity after delivery to rat lungs

(2008) Francesca Ungaro et al.   JOURNAL OF CONTROLLED RELEASE

In vitro dissolution studies of uranium bearing material in simulated lung fluid

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