FGF Signalling in the Self-Renewal of Colon Cancer Organoids

Cell type-dependent differential activation of ERK by oncogenic KRAS in colon cancer and intestinal epithelium

(2019) Raphael Brandt et al.   Nature Communications

A rectal cancer organoid platform to study individual responses to chemoradiation

(2019) Karuna Ganesh et al.   NATURE MEDICINE

Patient-derived organoids can predict response to chemotherapy in metastatic colorectal cancer patients

(2019) Salo N. Ooft et al.   Science Translational Medicine

Patient-derived organoids model treatment response of metastatic gastrointestinal cancers

(2018) Georgios Vlachogiannis et al.   SCIENCE

An overview of the binding models of FGFR tyrosine kinases in complex with small molecule inhibitors

(2017) Weiyan Cheng et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Cancer stem cells revisited

(2017) Eduard Batlle et al.   NATURE MEDICINE

A Colorectal Tumor Organoid Library Demonstrates Progressive Loss of Niche Factor Requirements during Tumorigenesis

(2016) Masayuki Fujii et al.   Cell Stem Cell

Self-renewal molecular mechanisms of colorectal cancer stem cells

(2016) Tianhui Pan et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Modeling Nonalcoholic Fatty Liver Disease with Human Pluripotent Stem Cell-Derived Immature Hepatocyte-Like Cells Reveals Activation of PLIN2 and Confirms Regulatory Functions of Peroxisome Proliferator-Activated Receptor Alpha

(2016) Nina Graffmann et al.   STEM CELLS AND DEVELOPMENT

Prospective Derivation of a Living Organoid Biobank of Colorectal Cancer Patients

(2015) Marc van de Wetering et al.   CELL

Stromal gene expression defines poor-prognosis subtypes in colorectal cancer

(2015) Alexandre Calon et al.   NATURE GENETICS

Preserved genetic diversity in organoids cultured from biopsies of human colorectal cancer metastases

(2015) Fleur Weeber et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CDH2 and CDH11 act as regulators of stem cell fate decisions

(2015) Stella Alimperti et al.   Stem Cell Research

Epiregulin: Roles in normal physiology and cancer

(2014) David J. Riese et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Resistance to Anti-EGFR Therapy in Colorectal Cancer: From Heterogeneity to Convergent Evolution

(2014) S. Misale et al.   Cancer Discovery

Wnt signaling in adult intestinal stem cells and cancer

(2013) Michaela Krausova et al.   CELLULAR SIGNALLING

Cell and tissue polarity in the intestinal tract during tumourigenesis: cells still know the right way up, but tissue organization is lost

(2013) A. Fatehullah et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

A Robust Method to Analyze Copy Number Alterations of Less than 100 kb in Single Cells Using Oligonucleotide Array CGH

(2013) Birte Möhlendick et al.   PLoS One

Mechanisms of FGFR-mediated carcinogenesis

(2012) Imran Ahmad et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

ID1 and ID3 Regulate the Self-Renewal Capacity of Human Colon Cancer-Initiating Cells through p21

(2012) Catherine A. O'Brien et al.   CANCER CELL

Comprehensive molecular characterization of human colon and rectal cancer

(2012)   NATURE

The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.

(2012) Ethan Cerami et al.   Cancer Discovery

Long-term Expansion of Epithelial Organoids From Human Colon, Adenoma, Adenocarcinoma, and Barrett's Epithelium

(2011) Toshiro Sato et al.   GASTROENTEROLOGY

Isolation and in vitro expansion of human colonic stem cells

(2011) Peter Jung et al.   NATURE MEDICINE

Stem Cell Proliferation in the Skin:  -Catenin Takes Over the Hippo Pathway

(2011) E. R. Flores et al.   Science Signaling

Analysis of Pluripotent Stem Cells by using Cryosections of Embryoid Bodies

(2010) Ismael C. Gomes et al.   Jove-Journal of Visualized Experiments

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

(2009) Toshiro Sato et al.   NATURE

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

TGFβ in Cancer

(2008) Joan Massagué   CELL