The biological activity of bispecific trastuzumab/pertuzumab plant biosimilars may be drastically boosted by disulfiram increasing formaldehyde accumulation in cancer cells
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Title
The biological activity of bispecific trastuzumab/pertuzumab plant biosimilars may be drastically boosted by disulfiram increasing formaldehyde accumulation in cancer cells
Authors
Keywords
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Journal
Scientific Reports
Volume 9, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2019-11-07
DOI
10.1038/s41598-019-52507-9
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Note: Only part of the references are listed.- Disulfiram and BKM120 in Combination with Chemotherapy Impede Tumor Progression and Delay Tumor Recurrence in Tumor Initiating Cell-Rich TNBC
- (2019) Ling Wu et al. Scientific Reports
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- (2019) Zhi Yang et al. BIOMEDICINE & PHARMACOTHERAPY
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- (2019) Claudio Vernieri et al. CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
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- (2019) Yue Hao et al. PLoS One
- Suppressing autophagy enhances disulfiram/copper-induced apoptosis in non-small cell lung cancer
- (2018) Xi Wu et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Blocking distinct interactions between Glioblastoma cells and their tissue microenvironment: A novel multi-targeted therapeutic approach
- (2018) Melanie Mettang et al. Scientific Reports
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- (2018) Sijia Huang et al. mAbs
- Mechanisms Underlying the Action and Synergism of Trastuzumab and Pertuzumab in Targeting HER2-Positive Breast Cancer
- (2018) Babak Nami et al. Cancers
- Human Endogenous Formaldehyde as an Anticancer Metabolite: Its Oxidation Downregulation May Be a Means of Improving Therapy
- (2018) Yuri L. Dorokhov et al. BIOESSAYS
- Pertuzumab and breast cancer: another piece in the anti-HER2 puzzle
- (2017) Lorenzo Gerratana et al. EXPERT OPINION ON BIOLOGICAL THERAPY
- The making of bispecific antibodies
- (2017) Ulrich Brinkmann et al. mAbs
- Alcohol-abuse drug disulfiram targets cancer via p97 segregase adaptor NPL4
- (2017) Zdenek Skrott et al. NATURE
- Plant-Made Antibodies: Properties and Therapeutic Applications
- (2017) Tatiana V. Komarova et al. CURRENT MEDICINAL CHEMISTRY
- Transcriptome-wide identification of mRNAs and lincRNAs associated with trastuzumab-resistance in HER2-positive breast cancer
- (2016) Callie R. Merry et al. Oncotarget
- Targeting HER2 for the Treatment of Breast Cancer
- (2015) Mothaffar F. Rimawi et al. Annual Review of Medicine
- Disulfiram-induced cytotoxicity and endo-lysosomal sequestration of zinc in breast cancer cells
- (2015) Helen L. Wiggins et al. BIOCHEMICAL PHARMACOLOGY
- Alternative molecular formats and therapeutic applications for bispecific antibodies
- (2015) Christoph Spiess et al. MOLECULAR IMMUNOLOGY
- Disulfiram (DSF) acts as a copper ionophore to induce copper-dependent oxidative stress and mediate anti-tumor efficacy in inflammatory breast cancer
- (2015) Jennifer L. Allensworth et al. Molecular Oncology
- Metabolic Methanol: Molecular Pathways and Physiological Roles
- (2015) Yuri L. Dorokhov et al. PHYSIOLOGICAL REVIEWS
- HER2-directed therapy: current treatment options for HER2-positive breast cancer
- (2015) Shahid Ahmed et al. Breast Cancer
- A conceptually new treatment approach for relapsed glioblastoma: Coordinated undermining of survival paths with nine repurposed drugs (CUSP9) by the International Initiative for Accelerated Improvement of Glioblastoma Care.
- (2015) Richard E. Kast et al. Oncotarget
- Inhibitory effect of Disulfiram/copper complex on non-small cell lung cancer cells
- (2014) Lincan Duan et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Endogenous Methanol Regulates Mammalian Gene Activity
- (2014) Tatiana V. Komarova et al. PLoS One
- Pertuzumab for the treatment of human epidermal growth factor receptor type 2-positive metastatic breast cancer
- (2013) C. Chung et al. AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY
- Bispecific Antibody to ErbB2 Overcomes Trastuzumab Resistance through Comprehensive Blockade of ErbB2 Heterodimerization
- (2013) B. Li et al. CANCER RESEARCH
- In vitro study on cytotoxicity and intracellular formaldehyde concentration changes after exposure to formaldehyde and its derivatives
- (2013) YJ Ke et al. HUMAN & EXPERIMENTAL TOXICOLOGY
- Recombinant antibody mixtures: Production strategies and cost considerations
- (2012) Søren K. Rasmussen et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- HER2-Associated Radioresistance of Breast Cancer Stem Cells Isolated from HER2-Negative Breast Cancer Cells
- (2012) N. Duru et al. CLINICAL CANCER RESEARCH
- Inhibition of protein–protein interaction of HER2–EGFR and HER2–HER3 by a rationally designed peptidomimetic
- (2012) Sashikanth Banappagari et al. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
- Disulfiram, and Disulfiram Derivatives as Novel Potential Anticancer Drugs Targeting the Ubiquitin Proteasome System in Both Preclinical and Clinical Studies
- (2011) F. R. Kona et al. CURRENT CANCER DRUG TARGETS
- Nonprofit drugs as the salvation of the world's healthcare systems: the case of Antabuse (disulfiram)
- (2011) Boris Cvek DRUG DISCOVERY TODAY
- Plant-Made Trastuzumab (Herceptin) Inhibits HER2/Neu+ Cell Proliferation and Retards Tumor Growth
- (2011) Tatiana V. Komarova et al. PLoS One
- High Affinity Antigen Recognition of the Dual Specific Variants of Herceptin Is Entropy-Driven in Spite of Structural Plasticity
- (2011) Jenny Bostrom et al. PLoS One
- Transient expression systems for plant-derived biopharmaceuticals
- (2010) Tatiana V Komarova et al. Expert Review of Vaccines
- Disulfiram is a DNA demethylating agent and inhibits prostate cancer cell growth
- (2010) Jianqing Lin et al. PROSTATE
- Disulfiram/copper complex inhibiting NFκB activity and potentiating cytotoxic effect of gemcitabine on colon and breast cancer cell lines
- (2009) Xiaoxia Guo et al. CANCER LETTERS
- Strongly Enhanced Antitumor Activity of Trastuzumab and Pertuzumab Combination Treatment on HER2-Positive Human Xenograft Tumor Models
- (2009) W. Scheuer et al. CANCER RESEARCH
- Resistance to Trastuzumab in Breast Cancer
- (2009) P. R. Pohlmann et al. CLINICAL CANCER RESEARCH
- High-Throughput Cell-Based Screening of 4910 Known Drugs and Drug-like Small Molecules Identifies Disulfiram as an Inhibitor of Prostate Cancer Cell Growth
- (2009) K. Iljin et al. CLINICAL CANCER RESEARCH
- Differential binding of human immunoagents and Herceptin to the ErbB2 receptor
- (2008) Fulvia Troise et al. FEBS Journal
- HER2 regulates the mammary stem/progenitor cell population driving tumorigenesis and invasion
- (2008) H Korkaya et al. ONCOGENE
- Generation of glyco-engineered Nicotiana benthamiana for the production of monoclonal antibodies with a homogeneous human-like N-glycan structure
- (2008) Richard Strasser et al. PLANT BIOTECHNOLOGY JOURNAL
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