Transient expression systems for plant-derived biopharmaceuticals

In vitro stability of Cucumber mosaic virus nanoparticles carrying a Hepatitis C virus-derived epitope under simulated gastrointestinal conditions and in vivo efficacy of an edible vaccine

(2010) M. Nuzzaci et al.   JOURNAL OF VIROLOGICAL METHODS

Immunogenic properties of chimeric potato virus X particles displaying the hepatitis C virus hypervariable region I peptide R9

(2010) Kerstin Uhde-Holzem et al.   JOURNAL OF VIROLOGICAL METHODS

Plant-specific glycosylation patterns in the context of therapeutic protein production

(2010) Véronique Gomord et al.   PLANT BIOTECHNOLOGY JOURNAL

Production of antibodies in plants: status after twenty years

(2010) Benoit De Muynck et al.   PLANT BIOTECHNOLOGY JOURNAL

The production of hemagglutinin-based virus-like particles in plants: a rapid, efficient and safe response to pandemic influenza

(2010) Marc-André D’Aoust et al.   PLANT BIOTECHNOLOGY JOURNAL

Monoclonal antibody produced in plants efficiently treats West Nile virus infection in mice

(2010) H. Lai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A DNA replicon system for rapid high-level production of virus-like particles in plants

(2009) Zhong Huang et al.   BIOTECHNOLOGY AND BIOENGINEERING

Transient protein expression in three Pisum sativum (green pea) varieties

(2009) Brian J. Green et al.   Biotechnology Journal

Plant-produced human growth hormone shows biological activity in a rat model

(2009) Shailaja Rabindran et al.   BIOTECHNOLOGY PROGRESS

Models of Antigen Receptor Activation in the Design of Vaccines

(2009) Eszter Molnar et al.   CURRENT PHARMACEUTICAL DESIGN

Mimotope vaccination – from allergy to cancer

(2009) Regina Knittelfelder et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Using plant cells as influenza vaccine substrates

(2009) Jessica A Chichester et al.   Expert Review of Vaccines

Expression of Hemagglutinin-Neuraminidase glycoprotein of Newcastle Disease Virus in agroinfiltrated Nicotiana benthamiana plants

(2009) Evangelina Gómez et al.   JOURNAL OF BIOTECHNOLOGY

Cowpea mosaic virus chimeric particles bearing the ectodomain of matrix protein 2 (M2E) of the influenza a virus: Production and characterization

(2009) Yu. A. Meshcheryakova et al.   MOLECULAR BIOLOGY

Transient co-expression for fast and high-yield production of antibodies with human-likeN-glycans in plants

(2009) Louis-P. Vézina et al.   PLANT BIOTECHNOLOGY JOURNAL

Production and characterization of an orally immunogenicPlasmodiumantigen in plants using a virus-based expression system

(2009) Diane E. Webster et al.   PLANT BIOTECHNOLOGY JOURNAL

Optimization of conditions for transient Agrobacterium-mediated gene expression assays in Arabidopsis

(2009) Mi Jung Kim et al.   PLANT CELL REPORTS

Hydrophobin Fusions for High-Level Transient Protein Expression and Purification in Nicotiana benthamiana

(2009) J. J. Joensuu et al.   PLANT PHYSIOLOGY

A Plant-Derived Recombinant Human Glucocerebrosidase Enzyme—A Preclinical and Phase I Investigation

(2009) David Aviezer et al.   PLoS One

Golden Gate Shuffling: A One-Pot DNA Shuffling Method Based on Type IIs Restriction Enzymes

(2009) Carola Engler et al.   PLoS One

Plant-based strategies aimed at expressing HIV antigens and neutralizing antibodies at high levels. Nef as a case study

(2009) Carla Marusic et al.   TRANSGENIC RESEARCH

Plant-made vaccine antigens and biopharmaceuticals

(2009) Henry Daniell et al.   TRENDS IN PLANT SCIENCE

Boosted expression of the SARS-CoV nucleocapsid protein in tobacco and its immunogenicity in mice

(2009) Nuoyan Zheng et al.   VACCINE

Immunological assessment of plant-derived avian flu H5/HA1 variants

(2009) S. Spitsin et al.   VACCINE

Plant-produced potato virus X chimeric particles displaying an influenza virus-derived peptide activate specific CD8+ T cells in mice

(2009) Chiara Lico et al.   VACCINE

Immunogenicity of hemagglutinin from A/Bar-headed Goose/Qinghai/1A/05 and A/Anhui/1/05 strains of H5N1 influenza viruses produced in Nicotiana benthamiana plants

(2009) Yoko Shoji et al.   VACCINE

Efficient generation of cowpea mosaicvirus empty virus-like particles by the proteolytic processing of precursors in insect cells and plants

(2009) Keith Saunders et al.   VIROLOGY

Insertion in the coding region of the movement protein improves stability of the plasmid encoding a tomato mosaic virus-based expression vector

(2008) Koji Dohi et al.   ARCHIVES OF VIROLOGY

Production of recombinant proteins in clonal root cultures using episomal expression vectors

(2008) Marina Skarjinskaia et al.   BIOTECHNOLOGY AND BIOENGINEERING

A model ofAgrobacterium tumefaciensvacuum infiltration into harvested leaf tissue and subsequent in planta transgene transient expression

(2008) Christopher W. Simmons et al.   BIOTECHNOLOGY AND BIOENGINEERING

Expression of HIV-1 antigens in plants as potential subunit vaccines

(2008) Ann Meyers et al.   BMC BIOTECHNOLOGY

Plant-produced vaccines: promise and reality

(2008) Edward P. Rybicki   DRUG DISCOVERY TODAY

Recent progress in the development of plant derived vaccines

(2008) Vidadi Yusibov et al.   Expert Review of Vaccines

Genetically engineered Tobacco mosaic virus as nanoparticle vaccines

(2008) Alison A McCormick et al.   Expert Review of Vaccines

A simple and effective system for foreign gene expression in plants via root absorption of agrobacterial suspension

(2008) L YANG et al.   JOURNAL OF BIOTECHNOLOGY

Viral vectors for production of recombinant proteins in plants

(2008) Chiara Lico et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Nicotiana benthamiana: Its History and Future as a Model for Plant–Pathogen Interactions

(2008) Michael M. Goodin et al.   MOLECULAR PLANT-MICROBE INTERACTIONS

Influenza virus-like particles produced by transient expression inNicotiana benthamianainduce a protective immune response against a lethal viral challenge in mice

(2008) Marc-André D’Aoust et al.   PLANT BIOTECHNOLOGY JOURNAL

Plant pharming of a full-sized, tumour-targeting antibody using different expression strategies

(2008) Maria Elena Villani et al.   PLANT BIOTECHNOLOGY JOURNAL

Extremely High-Level and Rapid Transient Protein Production in Plants without the Use of Viral Replication

(2008) F. Sainsbury et al.   PLANT PHYSIOLOGY

Agrobacterium tumefaciens-Induced Bacteraemia Does Not Lead to Reporter Gene Expression in Mouse Organs

(2008) Igor V. Petrunia et al.   PLoS One

Plant-produced idiotype vaccines for the treatment of non-Hodgkin's lymphoma: Safety and immunogenicity in a phase I clinical study

(2008) A. A. McCormick et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An efficient plant viral expression system generating orally immunogenic Norwalk virus-like particles

(2008) Luca Santi et al.   VACCINE

Plant-derived hemagglutinin protects ferrets against challenge infection with the A/Indonesia/05/05 strain of avian influenza

(2008) Yoko Shoji et al.   VACCINE

Development of a new cucumber mosaic virus-based plant expression vector with truncated 3a movement protein

(2008) Masaaki Fujiki et al.   VIROLOGY

Three heterologous proteins simultaneously expressed from a chimeric potyvirus: Infectivity, stability and the correlation of genome and virion lengths

(2008) Jani Kelloniemi et al.   VIRUS RESEARCH