Mimicking in-vivo exposures to drug combinations in-vitro: anti-tuberculosis drugs in lung lesions and the hollow fiber model of infection

Moxifloxacin target site concentrations in patients with pulmonary TB utilizing microdialysis: a clinical pharmacokinetic study

(2017) M Tobias Heinrichs et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

High-dose rifampicin, moxifloxacin, and SQ109 for treating tuberculosis: a multi-arm, multi-stage randomised controlled trial

(2017) Martin J Boeree et al.   LANCET INFECTIOUS DISEASES

Prediction of Drug Penetration in Tuberculosis Lesions

(2016) Jansy P. Sarathy et al.   ACS Infectious Diseases

Population Pharmacokinetic Analysis of Isoniazid, Acetylisoniazid, and Isonicotinic Acid in Healthy Volunteers

(2015) Kok-Yong Seng et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Cavitary Penetration of Levofloxacin among Patients with Multidrug-Resistant Tuberculosis

(2015) Russell R. Kempker et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Systematic Analysis of Hollow Fiber Model of Tuberculosis Experiments

(2015) Jotam G. Pasipanodya et al.   CLINICAL INFECTIOUS DISEASES

Strategic Regulatory Evaluation and Endorsement of the Hollow Fiber Tuberculosis System as a Novel Drug Development Tool: Figure 1.

(2015) Klaus Romero et al.   CLINICAL INFECTIOUS DISEASES

The association between sterilizing activity and drug distribution into tuberculosis lesions

(2015) Brendan Prideaux et al.   NATURE MEDICINE

Comprehensive physicochemical, pharmacokinetic and activity profiling of anti-TB agents

(2014) Suresh B. Lakshminarayana et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Analysis of Combination Drug Therapy to Develop Regimens with Shortened Duration of Treatment for Tuberculosis

(2014) George L. Drusano et al.   PLoS One

Feasibility of a Fixed-Dose Regimen of Pyrazinamide and Its Impact on Systemic Drug Exposure and Liver Safety in Patients with Tuberculosis

(2012) Tarjinder Sahota et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

A Semimechanistic Pharmacokinetic-Enzyme Turnover Model for Rifampin Autoinduction in Adult Tuberculosis Patients

(2012) Wynand Smythe et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

PK/PD: new insights for antibacterial and antiviral applications

(2008) S SCHMIDT et al.   CURRENT OPINION IN PHARMACOLOGY