Albumin evokes Ca2+-induced cell oxidative stress and apoptosis through TRPM2 channel in renal collecting duct cells reduced by curcumin

Increasing the TRPM2 Channel Expression in Human Neuroblastoma SH-SY5Y Cells Augments the Susceptibility to ROS-Induced Cell Death

(2019) Xinfang An et al.   Cells

Multiple molecular mechanisms form a positive feedback loop driving amyloid β42 peptide-induced neurotoxicity via activation of the TRPM2 channel in hippocampal neurons

(2018) Xin Li et al.   Cell Death & Disease

Alpha lipoic acid attenuates hypoxia-induced apoptosis, inflammation and mitochondrial oxidative stress via inhibition of TRPA1 channel in human glioblastoma cell line

(2018) Haci Ahmet Deveci et al.   BIOMEDICINE & PHARMACOTHERAPY

Curcumin enhances the effects of irinotecan on colorectal cancer cells through the generation of reactive oxygen species and activation of the endoplasmic reticulum stress pathway

(2017) Yan-Feng Huang et al.   Oncotarget

Involvement of TRPM2 and TRPV1 channels on hyperalgesia, apoptosis and oxidative stress in rat fibromyalgia model: Protective role of selenium

(2017) Esra Yüksel et al.   Scientific Reports

Activation of endogenous TRPV1 fails to induce overstimulation-based cytotoxicity in breast and prostate cancer cells but not in pain-sensing neurons

(2016) László Pecze et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Endogenous TRPV1 stimulation leads to the activation of the inositol phospholipid pathway necessary for sustained Ca 2+ oscillations

(2016) László Pecze et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Curcumin inhibits oxidative stress-induced TRPM2 channel activation, calcium ion entry and apoptosis values in SH-SY5Y neuroblastoma cells: Involvement of transfection procedure

(2016) Ahmi Öz et al.   MOLECULAR MEMBRANE BIOLOGY

Modulation of Diabetes-Induced Oxidative Stress, Apoptosis, and Ca2+ Entry Through TRPM2 and TRPV1 Channels in Dorsal Root Ganglion and Hippocampus of Diabetic Rats by Melatonin and Selenium

(2016) Mehmet Cemal Kahya et al.   MOLECULAR NEUROBIOLOGY

Endoplasmic reticulum stress drives proteinuria-induced kidney lesions via Lipocalin 2

(2016) Khalil El Karoui et al.   Nature Communications

Cancer-selective cytotoxic Ca2+ overload in acute myeloid leukemia cells and attenuation of disease progression in mice by synergistically acting polyphenols curcumin and carnosic acid

(2016) Stella Pesakhov et al.   Oncotarget

Curcumin inhibits activation of TRPM2 channels in rat hepatocytes

(2016) E. Kheradpezhouh et al.   Redox Biology

Altered calcium signaling in cancer cells

(2015) Teneale A. Stewart et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Routes of Ca2+Shuttling during Ca2+Oscillations

(2015) László Pecze et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protection of curcumin against amyloid-β-induced cell damage and death involves the prevention from NMDA receptor-mediated intracellular Ca2+elevation

(2015) Han-Chang Huang et al.   JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION

Curcumin inhibits apoptosis by regulating intracellular calcium release, reactive oxygen species and mitochondrial depolarization levels in SH-SY5Y neuronal cells

(2015) Abdülhadi Cihangir Uğuz et al.   JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION

CKD Prevalence Varies across the European General Population

(2015) K. Bru ck et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

ROS and oxidative stress in CKD patients: is it the mitochondria that keeps CKD patients in bed?

(2015) H. Hagmann et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Homocysteine and cytosolic GSH depletion induce apoptosis and oxidative toxicity through cytosolic calcium overload in the hippocampus of aged mice: Involvement of TRPM2 and TRPV1 channels

(2015) İ.S. Övey et al.   NEUROSCIENCE

Curcumin protects against gallic acid-induced oxidative stress, suppression of glutathione antioxidant defenses, hepatic and renal damage in rats

(2015) Sunny O. Abarikwu et al.   RENAL FAILURE

Current and Potential Therapeutic Strategies for Hemodynamic Cardiorenal Syndrome

(2015) Yoshitsugu Obi et al.   CardioRenal Medicine

The balance of powers: Redox regulation of fibrogenic pathways in kidney injury

(2015) Daryl M. Okamura et al.   Redox Biology

ROS Function in Redox Signaling and Oxidative Stress

(2014) Michael Schieber et al.   CURRENT BIOLOGY

Calcium Ion – The Key Player in Cerebral Ischemia

(2014) V.S. Kumar et al.   CURRENT MEDICINAL CHEMISTRY

TRPM2 mediates ischemic kidney injury and oxidant stress through RAC1

(2014) Guofeng Gao et al.   JOURNAL OF CLINICAL INVESTIGATION

Lys1110of TRPM2 is critical for channel activation

(2013) Taek-Keun Kim et al.   BIOCHEMICAL JOURNAL

Modulation of albumin-induced endoplasmic reticulum stress in renal proximal tubule cells by upregulation of mapk phosphatase-1

(2013) Alejandra Gorostizaga et al.   CHEMICO-BIOLOGICAL INTERACTIONS

ATP Releasing Connexin 30 Hemichannels Mediate Flow-Induced Calcium Signaling in the Collecting Duct

(2013) Per Svenningsen et al.   Frontiers in Physiology

Renoprotective effect of the antioxidant curcumin: Recent findings

(2013) Joyce Trujillo et al.   Redox Biology

Reprint of “Glutathione Peroxidase Activity in Selenium-Deficient Rat Liver”

(2012) Richard A. Lawrence   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Curcumin Suppresses T Cell Activation by Blocking Ca 2+ Mobilization and Nuclear Factor of Activated T Cells (NFAT) Activation

(2012) Christian Kliem et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TRPM2 channel protective properties of N-acetylcysteine on cytosolic glutathione depletion dependent oxidative stress and Ca2+ influx in rat dorsal root ganglion

(2012) C Özgül et al.   PHYSIOLOGY & BEHAVIOR

Loss of glutathione homeostasis associated with neuronal senescence facilitates TRPM2 channel activation in cultured hippocampal pyramidal neurons

(2012) Jillian C Belrose et al.   Molecular Brain

Discovery of curcumin, a component of golden spice, and its miraculous biological activities

(2011) Subash C Gupta et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Lipocalin-2 (24p3/Neutrophil Gelatinase-associated Lipocalin (NGAL)) Receptor Is Expressed in Distal Nephron and Mediates Protein Endocytosis

(2011) Christian Langelueddecke et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ratiometric high-resolution imaging of JC-1 fluorescence reveals the subcellular heterogeneity of astrocytic mitochondria

(2011) Vera C. Keil et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

ER Tubules Mark Sites of Mitochondrial Division

(2011) J. R. Friedman et al.   SCIENCE

Determination of Mitochondrial Membrane Potential and Reactive Oxygen Species in Live Rat Cortical Neurons

(2011) Dinesh C. Joshi et al.   Jove-Journal of Visualized Experiments

Decreased renal corin expression contributes to sodium retention in proteinuric kidney diseases

(2010) Danny Polzin et al.   KIDNEY INTERNATIONAL

Mitochondrial calcium and the permeability transition in cell death

(2009) John J. Lemasters et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Production, concentration and titration of pseudotyped HIV-1-based lentiviral vectors

(2009) Robert H Kutner et al.   Nature Protocols

Effects of antioxidants on calcium influx through TRPM2 channels in transfected cells activated by hydrogen peroxide

(2008) Mustafa Nazıroğlu et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES