Leptin, Obesity, and Leptin Resistance: Where Are We 25 Years Later?
Published 2019 View Full Article
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Title
Leptin, Obesity, and Leptin Resistance: Where Are We 25 Years Later?
Authors
Keywords
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Journal
Nutrients
Volume 11, Issue 11, Pages 2704
Publisher
MDPI AG
Online
2019-11-09
DOI
10.3390/nu11112704
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- (2019) Martina Theresa Hackl et al. Nature Communications
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- (2018) Warren W. Pan et al. NATURE REVIEWS NEUROSCIENCE
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- (2018) Maximilian Kleinert et al. Molecular Metabolism
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- (2018) Luke Harrison et al. INTERNATIONAL JOURNAL OF OBESITY
- Maternal Obesity in the Mouse Compromises the Blood-Brain Barrier in the Arcuate Nucleus of Offspring
- (2016) Dong Won Kim et al. ENDOCRINOLOGY
- Hypothalamic leptin action is mediated by histone deacetylase 5
- (2016) Dhiraj G. Kabra et al. Nature Communications
- Meta-chlorophenylpiperazine enhances leptin sensitivity in diet-induced obese mice
- (2015) Chunling Yan et al. BRITISH JOURNAL OF PHARMACOLOGY
- Leptin and Insulin Act on POMC Neurons to Promote the Browning of White Fat
- (2015) Garron T. Dodd et al. CELL
- Diet-Induced Obese Mice Retain Endogenous Leptin Action
- (2015) Nickki Ottaway et al. Cell Metabolism
- PASylation of Murine Leptin Leads to Extended Plasma Half-Life and Enhanced in Vivo Efficacy
- (2015) Volker Morath et al. MOLECULAR PHARMACEUTICS
- Peptides and the blood–brain barrier
- (2015) William A. Banks PEPTIDES
- Therapeutic potential of flurbiprofen against obesity in mice
- (2014) Toru Hosoi et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
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- (2014) Eglantine Balland et al. Cell Metabolism
- Flurbiprofen ameliorated obesity by attenuating leptin resistance induced by endoplasmic reticulum stress
- (2014) Toru Hosoi et al. EMBO Molecular Medicine
- Clusterin/ApoJ enhances central leptin signaling through Lrp2-mediated endocytosis
- (2014) K. Byun et al. EMBO REPORTS
- Endospanin 1 silencing in the hypothalamic arcuate nucleus contributes to sustained weight loss of high fat diet obese mice
- (2014) V Vauthier et al. GENE THERAPY
- Pluronic modified leptin with increased systemic circulation, brain uptake and efficacy for treatment of obesity
- (2014) Xiang Yi et al. JOURNAL OF CONTROLLED RELEASE
- GLP-1/Glucagon Coagonism Restores Leptin Responsiveness in Obese Mice Chronically Maintained on an Obesogenic Diet
- (2013) C. Clemmensen et al. DIABETES
- Reciprocal cross-regulation between RNF41 and USP8 controls cytokine receptor sorting and processing
- (2013) L. De Ceuninck et al. JOURNAL OF CELL SCIENCE
- Restoration of leptin responsiveness in diet-induced obese mice using an optimized leptin analog in combination with exendin-4 or FGF21
- (2012) Timo D. Müller et al. JOURNAL OF PEPTIDE SCIENCE
- Deficiency of PTP1B in POMC neurons leads to alterations in energy balance and homeostatic response to cold exposure
- (2011) Bart C. De Jonghe et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Effects of chronic weight perturbation on energy homeostasis and brain structure in mice
- (2011) Y. Ravussin et al. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
- Intranasal Leptin Reduces Appetite and Induces Weight Loss in Rats with Diet-Induced Obesity (DIO)
- (2011) Carla Schulz et al. ENDOCRINOLOGY
- Endospanins Regulate a Postinternalization Step of the Leptin Receptor Endocytic Pathway
- (2011) Karin Séron et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Fall in Leptin Concentration Is a Major Determinant of the Metabolic Adaptation Induced by Caloric Restriction Independently of the Changes in Leptin Circadian Rhythms
- (2011) Virgile Lecoultre et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Functional Role of Suppressor of Cytokine Signaling 3 Upregulation in Hypothalamic Leptin Resistance and Long-Term Energy Homeostasis
- (2010) A. S. Reed et al. DIABETES
- PTP1B and SHP2 in POMC neurons reciprocally regulate energy balance in mice
- (2010) Ryoichi Banno et al. JOURNAL OF CLINICAL INVESTIGATION
- Transport across the Blood-Brain Barrier of Pluronic Leptin
- (2010) T. O. Price et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Inhibition of PTP1B by Trodusquemine (MSI-1436) Causes Fat-specific Weight Loss in Diet-induced Obese Mice
- (2010) Kristen A. Lantz et al. Obesity
- The design of barriers in the hypothalamus allows the median eminence and the arcuate nucleus to enjoy private milieus: The former opens to the portal blood and the latter to the cerebrospinal fluid
- (2010) Esteban M. Rodríguez et al. PEPTIDES
- Multi-hormonal weight loss combinations in diet-induced obese rats: Therapeutic potential of cholecystokinin?
- (2010) James L. Trevaskis et al. PHYSIOLOGY & BEHAVIOR
- Endoplasmic Reticulum Stress Plays a Central Role in Development of Leptin Resistance
- (2009) Lale Ozcan et al. Cell Metabolism
- Leptin-based glycopeptide induces weight loss and simultaneously restores fertility in animal models
- (2009) I. Kovalszky et al. DIABETES OBESITY & METABOLISM
- Pegylated Leptin Antagonist Is a Potent Orexigenic Agent: Preparation and Mechanism of Activity
- (2009) Eran Elinav et al. ENDOCRINOLOGY
- Tat-modified Leptin is more Accessible to Hypothalamus through Brain-blood Barrier with a Significant Inhibition of Body-weight Gain in High-fat-diet Fed Mice
- (2009) C. Zhang et al. EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES
- Requirement of Bardet-Biedl syndrome proteins for leptin receptor signaling
- (2009) Seongjin Seo et al. HUMAN MOLECULAR GENETICS
- Enhanced Weight Loss With Pramlintide/Metreleptin: An Integrated Neurohormonal Approach to Obesity Pharmacotherapy
- (2009) Eric Ravussin et al. Obesity
- High-Fat Diet Induces Apoptosis of Hypothalamic Neurons
- (2009) Juliana C. Moraes et al. PLoS One
- Astrocyte Leptin Receptor (ObR) and Leptin Transport in Adult-Onset Obese Mice
- (2008) Weihong Pan et al. ENDOCRINOLOGY
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- (2008) Michael Rosenbaum et al. JOURNAL OF CLINICAL INVESTIGATION
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