Polydatin Inhibits NLRP3 Inflammasome in Dry Eye Disease by Attenuating Oxidative Stress and Inhibiting the NF-κB Pathway

The Protective Effect of Polygonum cuspidatum (PCE) Aqueous Extract in a Dry Eye Model

(2018) Bongkyun Park et al.   Nutrients

Conjunctival Inflammatory Gene Expression Profiling in Dry Eye Disease: Correlations With HLA-DRA and HLA-DRB1

(2018) Karima Kessal et al.   Frontiers in Immunology

Inhibiting effects of dietary polyphenols on chronic eye diseases

(2017) Zhihan Xu et al.   Journal of Functional Foods

Polydatin protects the respiratory system from PM2.5 exposure

(2017) Xiao-Dan Yan et al.   Scientific Reports

Mechanism and Regulation of NLRP3 Inflammasome Activation

(2016) Yuan He et al.   TRENDS IN BIOCHEMICAL SCIENCES

Topical Application of Apricot Kernel Extract Improves Dry Eye Symptoms in a Unilateral Exorbital Lacrimal Gland Excision Mouse

(2016) Chan-Sik Kim et al.   Nutrients

Relationships between human vitality and mitochondrial respiratory parameters, reactive oxygen species production and dNTP levels in peripheral blood mononuclear cells

(2016) Scott Maynard et al.   Aging-US

Molecular mechanisms regulating NLRP3 inflammasome activation

(2015) Eun-Kyeong Jo et al.   Cellular & Molecular Immunology

Reactive oxygen species activated NLRP3 inflammasomes initiate inflammation in hyperosmolarity stressed human corneal epithelial cells and environment-induced dry eye patients

(2015) Qinxiang Zheng et al.   EXPERIMENTAL EYE RESEARCH

Upregulation of NLRP3 Inflammasome in the Tears and Ocular Surface of Dry Eye Patients

(2015) Liangliang Niu et al.   PLoS One

Oxidative Stress Markers Induced by Hyperosmolarity in Primary Human Corneal Epithelial Cells

(2015) Ruzhi Deng et al.   PLoS One

Extraorbital Lacrimal Gland Excision

(2014) William Stevenson et al.   CORNEA

Reactive oxygen species activated NLRP3 inflammasomes prime environment-induced murine dry eye

(2014) Qinxiang Zheng et al.   EXPERIMENTAL EYE RESEARCH

The role and treatment of inflammation in dry eye disease

(2014) Ayse Yagci et al.   INTERNATIONAL OPHTHALMOLOGY

Polydatin inhibits growth of lung cancer cells by inducing apoptosis and causing cell cycle arrest

(2013) YUSONG ZHANG et al.   Oncology Letters

Dry Eye Disease

(2012) William Stevenson   ARCHIVES OF OPHTHALMOLOGY

Polydatin ameliorates experimental diabetes-induced fibronectin through inhibiting the activation of NF-κB signaling pathway in rat glomerular mesangial cells

(2012) Xi Xie et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Cutting Edge: Reactive Oxygen Species Inhibitors Block Priming, but Not Activation, of the NLRP3 Inflammasome

(2011) F. Bauernfeind et al.   JOURNAL OF IMMUNOLOGY

Interleukin-1 as a Phenotypic Immunomodulator in Keratinizing Squamous Metaplasia of the Ocular Surface in Sjögren's Syndrome

(2010) Ying-Ting Chen et al.   AMERICAN JOURNAL OF PATHOLOGY

Innate instruction of adaptive immunity revisited: the inflammasome

(2009) Stephanie C. Eisenbarth et al.   EMBO Molecular Medicine

Inflammasomes: guardians of cytosolic sanctity

(2008) Mohamed Lamkanfi et al.   IMMUNOLOGICAL REVIEWS