Review
Medicine, Research & Experimental
Naoual El Menyiy, Aicha El Allam, Sara Aboulaghras, Imane Jaouadi, Saad Bakrim, Nasreddine El Omari, Mohammad Ali Shariati, Alevtin Miftakhutdinov, Polrat Wilairatana, Mohammad S. Mubarak, Abdelhakim Bouyahya
Summary: Autoimmune diseases are caused by the overactivity of the immune system towards self-constituents. Natural compounds derived from medicinal plants have shown potential in modulating the inflammatory responses of these diseases, presenting a promising approach for treatment and prevention.
BIOMEDICINE & PHARMACOTHERAPY
(2022)
Review
Biochemistry & Molecular Biology
Priscila Schilrreff, Ulrike Alexiev
Summary: This review discusses the crucial role of chronic inflammation in chronic wounds and its close association with immune regulation. The dysregulation of the immune system leads to persistent inflammation and impaired wound healing, resulting in chronic skin wounds. Furthermore, it explores the potential of natural bioactive compounds in wound treatment, particularly focusing on compounds with antioxidant, anti-inflammatory, and antibacterial activities, as well as recent advancements in wound treatments utilizing nanotechnology or new biomaterial platforms.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Review
Microbiology
Shankar Prasad Sha, Debabrata Modak, Sourav Sarkar, Sudipta Kumar Roy, Sumit Prasad Sah, Kriti Ghatani, Soumen Bhattacharjee
Summary: Fruit waste has potential value and can be a rich source of secondary metabolites with multiple biological activities. By extracting and recovering bioactive compounds from waste, they can be applied in pharmaceuticals, nutraceuticals, and value-added products, potentially combating chronic diseases.
FRONTIERS IN MICROBIOLOGY
(2023)
Review
Immunology
Paraskevi C. Fragkou, Dareilena Karaviti, Michael Zemlin, Chrysanthi Skevaki
Summary: The first 1000 days of life, including the intrauterine period, are crucial for human development, with nutrition playing a key role in proper child development and affecting the composition of the gut microbiota. The gut microbiota, comprising various microorganisms, is highly influenced by diet and lifestyle, in turn affecting the immune system in complex ways. Many noncommunicable diseases associated with dysbiosis are programmed during childhood, highlighting the importance of nutrition on microbiota composition and the development of such diseases.
FRONTIERS IN IMMUNOLOGY
(2021)
Article
Health Care Sciences & Services
Zhenni Ni, Yiying Wang, Yuxing Qian
Summary: The study found that most chronic disease management apps in China have privacy policies, but the compliance rate of the policy content is low, especially in terms of information storage and protection. Furthermore, the scoring rate for rights of personal information subjects is generally low, indicating that China has a long way to go in terms of compliance around personal privacy protection.
JMIR MHEALTH AND UHEALTH
(2021)
Review
Nutrition & Dietetics
Chiara Frazzoli, Gerardo Grasso, Danladi Chiroma Husaini, Doris Nnenna Ajibo, Fortune Chiemelie Orish, Orish E. Orisakwe
Summary: Despite a high disease burden, the African continent has reported the lowest death rate with over 6 million coronavirus pandemic deaths. This resilience is attributed to climate, weather conditions, herd immunity, repeated exposure to infectious organisms, and a large youth population. Functional foods, herbal remedies, and dietary supplements containing micronutrients and bioactive compounds also contribute to immune system support.
Review
Food Science & Technology
Aurora Garza-Juarez, Esther Perez-Carrillo, Eder Ubaldo Arredondo-Espinoza, Jose Francisco Islas, Diego Francisco Benitez-Chao, Erandi Escamilla-Garcia
Summary: The high rate of deaths from noncommunicable diseases (NCDs) worldwide is primarily caused by poor diets lacking in nutrients and lifestyle and environmental factors that contribute to predisposing factors. International organizations such as the WHO, PAHO, and FAO have been developing strategic plans to promote food security and nutrition through government and economic policies. This review highlights the importance of functional foods and their bioactive compounds, known as nutraceuticals, in preventing and treating NCDs, considering the multifactorial aspects of these diseases.
Review
Food Science & Technology
Teresa Pinto, Alfredo Aires, Fernanda Cosme, Eunice Bacelar, Maria Cristina Morais, Ivo Oliveira, Jorge Ferreira-Cardoso, Rosario Anjos, Alice Vilela, Berta Goncalves
Summary: Polyphenols and volatile compounds are crucial for the quality and characteristics of vegetables and medicinal and aromatic plants, possessing various bioactivities and disease prevention properties. Researchers are focusing on polyphenols, volatile compounds, and the new challenges in enhancing positive characteristics of plants.
Article
Biochemistry & Molecular Biology
Shweta Sharma, Viveka Katoch, Satish Kumar, Subhrajyoti Chatterjee
Summary: Vegetables are essential components of a healthy diet, providing a wide range of nutrients and functional compounds that protect against disease. The color of vegetables plays a crucial role in assessing maturity and acceptability, with colored vegetables containing bioactive compounds with various health benefits. There is a shift towards consuming fresh fruits and vegetables for a disease-free life, leading to a focus on nutrition security and the development of color-rich cultivars with enhanced bioactive compounds.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY
(2021)
Review
Food Science & Technology
Inderjeet Kaur, Arun Dev Sharma, Mrinal Samtiya, Gema Pereira-Caro, Raquel Rodriguez-Solana, Tejpal Dhewa, Jose Manuel Moreno-Rojas
Summary: Underutilized fruit-bearing plants in nature have great potential in contributing to food sustainability, revenue generation, and ecological stability. This review article provides a comprehensive summary of 14 underutilized plants, highlighting their potential applications in various industries such as food and pharmaceuticals. The bioactive compounds found in different parts of these plants, such as fruits, leaves, and bark, have significant phytonutrient significance and exhibit diverse biological activities, making them alternative sources for therapeutic bioactive compounds.
EUROPEAN FOOD RESEARCH AND TECHNOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Flora C. Amagloh, Archileo N. Kaaya, Gaston A. Tumuhimbise, Arnold Katungisa, Francis K. Amagloh, Benard Yada
Summary: The bioactive compounds and antioxidant activities in sweetpotato storage roots are impacted by different cooking methods, with unpeeled sweetpotatoes containing more bioactive compounds and antioxidants. Microwaving retains the highest level of vitamin C among the cooking methods.
Review
Food Science & Technology
Esther Ramirez-Moreno, Jose Arias-Rico, Reyna Cristina Jimenez-Sanchez, Diego Estrada-Luna, Angelica Sarai Jimenez-Osorio, Quinatzin Yadira Zafra-Rojas, Jose Alberto Ariza-Ortega, Olga Rocio Flores-Chavez, Lizbeth Morales-Castillejos, Eli Mireya Sandoval-Gallegos
Summary: Obesity is a disease characterized by inflammation in adipose tissue, caused by immune cell infiltration, increased proinflammatory molecule secretion, and decreased anti-inflammatory molecule secretion. It also increases the risk of cardiovascular diseases, diabetes, and cancer. Natural products such as polyphenols and fiber have potential anti-inflammatory effects and play an important role in the prevention and treatment of obesity and other non-communicable diseases.
Review
Biochemistry & Molecular Biology
Marco Bocchetti, Marianna Scrima, Federica Melisi, Amalia Luce, Rossella Sperlongano, Michele Caraglia, Silvia Zappavigna, Alessia Maria Cossu
Summary: lncRNAs play a crucial role in regulating gene transcription during inflammatory responses, and recent studies have shown their dysregulation in human diseases is linked to immune mechanisms, offering insights into resolving complex disease relationships.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Review
Food Science & Technology
Shengyu Liu, Donald Grierson, Wanpeng Xi
Summary: This review provides a comprehensive understanding of the distribution, properties, and environmental response of bitter compounds in fruits and vegetables. It also discusses the potential applications of bitter compounds in breeding, agricultural technologies, and the development of natural pesticides and health-promoting medicines.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Article
Cardiac & Cardiovascular Systems
Dong D. Wang, Yanping Li, Shilpa N. Bhupathiraju, Bernard A. Rosner, Qi Sun, Edward L. Giovannucci, Eric B. Rimm, JoAnn E. Manson, Walter C. Willett, Meir J. Stampfer, Frank B. Hu
Summary: The study found that consuming approximately 5 servings of fruits and vegetables per day was associated with lower total mortality and mortality from cancer, cardiovascular disease, and respiratory disease. Higher intake beyond this level did not provide additional risk reduction.
Article
Nutrition & Dietetics
Rosa Casas, Margarida Ribo-Coll, Emilio Ros, Montserrat Fito, Rosa-Maria Lamuela-Raventos, Jordi Salas-Salvado, Itziar Zazpe, Miguel-Angel Martinez-Gonzalez, Jose Sorli, Ramon Estruch, Emilio Sacanella
Summary: This study assessed the adherence to the Mediterranean diet and cardiovascular risk factors in middle-aged and elderly participants, finding similar improvements in both groups after 3 years. It indicates that regardless of age, improving dietary habits and managing cardiovascular risk factors are achievable.
EUROPEAN JOURNAL OF NUTRITION
(2022)
Article
Cardiac & Cardiovascular Systems
Dimitrios Tsiachris, Christos-Konstantinos Antoniou, Ioannis Doundoulakis, Panagiota Manolakou, Athanasios Kordalis, Dimitrios Konstantinou, Konstantinos Gatzoulis, Konstantinos Tsioufis, Christodoulos Stefanadis
Summary: This study compared the clinical outcomes of a three-dimensional electroanatomical mapping (3D-EAM)-based strategy targeting slow pathway (SP) elimination with the conventional fluoroscopic approach in atrioventricular node reentrant tachycardia (AVNRT) ablation. The results showed that 3D-EAM improved procedural parameters, reduced fluoroscopy time and dose, and increased SP elimination frequency. Follow-up results demonstrated lower recurrence rates and redo procedure rates in the 3D-EAM-based group.
JOURNAL OF ARRHYTHMIA
(2022)
Article
Food Science & Technology
Sara Castro-Barquero, Rosa Casas, Eric B. Rimm, Anna Tresserra-Rimbau, Dora Romaguera, J. Alfredo Martinez, Jordi Salas-Salvado, Miguel A. Martinez-Gonzalez, Josep Vidal, Miguel Ruiz-Canela, Jadwiga Konieczna, Emilio Sacanella, Jesus Francisco Garcia-Gavilan, Montse Fito, Ana Garcia-Arellano, Ramon Estruch
Summary: This study found that excessive visceral adipose tissue is associated with increased secretion of pro-inflammatory molecules, leading to systemic inflammation and obesity-related metabolic disturbances. The reduction in visceral adipose tissue is associated with improvements in various inflammatory and adiposity markers, especially insulin, c-peptide, and PAI-1 levels, which may contribute to a decrease in cardiometabolic disturbances observed in obesity.
MOLECULAR NUTRITION & FOOD RESEARCH
(2023)
Article
Biochemistry & Molecular Biology
Emily P. Laveriano-Santos, Paola Quifer-Rada, Maria Marhuenda-Munoz, Camila Arancibia-Riveros, Anna Vallverdu-Queralt, Anna Tresserra-Rimbau, Ana Maria Ruiz-Leon, Rosa Casas, Ramon Estruch, Patricia Bodega, Mercedes de Miguel, Amaya de Cos-Gandoy, Jesus Martinez-Gomez, Gloria Santos-Beneit, Juan M. Fernandez-Alvira, Rodrigo Fernandez-Jimenez, Rosa M. Lamuela-Raventos
Summary: The study found that gallic acid, urolithin A, and urolithin B were inversely associated with the prevalence of MetS or some of its clinical features in adolescents.
Article
Nutrition & Dietetics
Indira Paz-Graniel, Montserrat Fito, Emilio Ros, Pilar Buil-Cosiales, Dolores Corella, Nancy Babio, J. Alfredo Martinez, Angel M. Alonso-Gomez, Julia Warnberg, Jesus Vioque, Dora Romaguera, Jose Lopez-Miranda, Ramon Estruch, Francisco J. Tinahones, Jose Lapetra, Lluis Serra-Majem, Aurora Bueno-Cavanillas, Josep A. Tur, Vicente Martin-Sanchez, Xavier Pinto, Jose Juan Gaforio, Pilar Matia-Martin, Josep Vidal, Clotilde Vazquez, Lidia Daimiel, Jesus F. Garcia-Gavilan, Estefania Toledo, Stephanie K. Nishi, Jose Sorli, Olga Castaner, Antonio Garcia-Rios, Manoli Garcia de la Hera, Francisco Javier Baron-Lopez, Miguel Ruiz-Canela, Marga Morey, Rosa Casas, Eva Maria Garrido-Garrido, Lucas Tojal-Sierra, Jose C. Fernandez-Garcia, Zenaida Vazquez-Ruiz, Rebeca Fernandez-Carrion, Albert Goday, Patricia J. Pena-Orihuela, Laura Compan-Gabucio, Helmut Schroder, Miguel A. Martinez-Gonzalez, Jordi Salas-Salvado
Summary: The COVID-19 pandemic has affected the ongoing PREDIMED-Plus study on weight-loss and cardiovascular disease prevention. Mitigating strategies were implemented to maintain the trial's integrity and minimize the effects on adiposity.
FRONTIERS IN NUTRITION
(2023)
Editorial Material
Nutrition & Dietetics
Olga Castaner, Anna Tresserra-Rimbau, Letizia Bresciani, Rosa Casas
FRONTIERS IN NUTRITION
(2023)
Article
Nutrition & Dietetics
Jiaqi Ni, Stephanie K. Nishi, Nancy Babio, Emilio Ros, F. Javier Basterra-Gortari, Dolores Corella, O. Castaner, J. Alfredo Martinez, Angel M. Alonso-Gomez, Julia Warnberg, Jesus Vioque, Dora Romaguera, Jose Lopez-Miranda, Ramon Estruch, Francisco J. Tinahones, Jose Manuel Santos-Lozano, Lluis Serra-Majem, Naomi Cano-Ibanez, Josep A. Tur, Jose Manuel Fernandez-Garcia, Xavier Pinto, Miguel Delgado-Rodriguez, Pilar Matia-Martin, Josep Vidal, Clotilde Vazquez, Lidia Daimiel, Fernando Fernandez-Aranda, Miguel Ruiz-Canela, Cristina Mestres Sola, Olga Portoles, Aleix Sala-Vila, Antonio Garcia-Rios, Laura Maria Compan-Gabucio, Enrique Gomez-Gracia, M. Angeles Zulet, Alice Chaplin, Rosa Casas, Silvia Martinez-Diz, Lucas Tojal-Sierra, Ana Maria Gomez-Perez, Estefania Toledo, Santiago Rios, Carolina Ortega-Azorin, Rafael de la Torre, Patricia J. Pena-Orihuela, Manuela Garcia-de la Hera, Carmen Sayon-Orea, Mireia Malcampo, PREDIMED Plus Investigators
Summary: This study aimed to evaluate the association between nut consumption and changes in cognitive performance in older adults. The findings suggest that frequent nut consumption is associated with a smaller decline in cognitive performance in older adults.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2023)
Article
Nutrition & Dietetics
Irene Casas, Ayako Nakaki, Rosalia Pascal, Sara Castro-Barquero, Lina Youssef, Mariona Genero, Leticia Benitez, Marta Larroya, Maria Laura Boutet, Giulia Casu, Alex Gomez-Gomez, Oscar J. Pozo, Ivette Morilla, Anabel Martinez-aran, Eduard Vieta, Maria Dolores Gomez-Roig, Rosa Casas, Ramon Estruch, Eduard Gratacos, Fatima Crispi, Francesca Crovetto
Summary: A study investigated the effects of a Mediterranean diet intervention on stress, well-being, and sleep quality in pregnant women. The results showed that pregnant women who followed a Mediterranean diet had reduced stress and anxiety, and improved sleep quality.
Article
Cardiac & Cardiovascular Systems
Sandra Gonzalez-Palacios, Alejandro Oncina-Canovas, Manuela Garcia-de-la-Hera, Miguel Angel Martinez-Gonzalez, Jordi Salas-Salvado, Dolores Corella, Helmut Schroder, J. Alfredo Martinez, Angel M. Alonso-Gomez, Julia Warnberg, Dora Romaguera, Jose Lopez-Miranda, Ramon Estruch, Francisco J. Tinahones, Jose Lapetra, J. Luis Serra-Majem, Naomi Cano-Ibanez, Josep A. Tur, Vicente Martin-Sanchez, Xavier Pinto, Miguel Delgado-Rodriguez, Pilar Matia-Martin, Josep Vidal, Clotilde Vazquer, Lidia Daimiel, Emili Ros, Maira Bes-Rastrollo, Alessandro Atzeni, Jose Sorli, M. Dolors Zomeno, Patricia J. Pena-Orihuela, Laura M. Compan-Gabucio, Francisco J. Baron-Lopez, Maria Angeles Zulet, Jadwiga Konieczna, Rosa M. Casas, Eva M. Garrido-Garrido, Lucas Tojal-Sierra, Ana M. Gomez-Perez, Miguel Ruiz-Canela, Antoni Palau, Carmen Saiz, Karla A. Perez-Vega, Antonio Garcia-Rios, Laura Torres-Collado, Javier Basterra-Gortari, Tany E. Garciduenas-Fimbres, Mireia Malcampo, Jesus Vioque, PREDIMED-PLUS Trial investigators
Summary: This study examined the association between changes in ultra-processed food (UPF) consumption and cardiometabolic risk (CMR) factors. The findings revealed that increased UPF consumption was associated with adverse changes in CMR factors among adults with metabolic syndrome.
Article
Environmental Sciences
Silvia Garcia, Rosario Pastor, Margalida Monserrat-Mesquida, Laura Alvarez-Alvarez, Maria Rubin-Garcia, Miguel Angel Martinez-Gonzalez, Jordi Salas-Salvado, Dolores Corella, Montserrat Fito, J. Alfredo Martinez, Lucas Tojal-Sierra, Julia Warnberg, Jesus Vioque, Dora Romaguera, Jose Lopez-Miranda, Ramon Estruch, Francisco J. Tinahones, Jose Manuel Santos-Lozano, Lluis Serra-Majem, Naomi Cano-Ibanez, Xavier Pinto, Miguel Delgado-Rodriguez, Pilar Matia-Martin, Josep Vidal, Clotilde Vazquez, Lidia Daimiel, Emili Ros, Pilar Buil-Cosiales, Maria Angeles Martinez-Rodriguez, Oscar Coltell, Olga Castaner, Antonio Garcia-Rios, Concepcion Barcelo, Enrique Gomez-Gracia, Maria Angeles Zulet, Jadwiga Konieczna, Rosa Casas, Paloma Masso-Guijarro, Leire Goicolea-Guemez, Maria Rosa Bernal-Lopez, Maira Bes-Rastrollo, Sangeetha Shyam, Jose I. Gonzalez, Maria Dolores Zomeno, Patricia J. Pena-Orihuela, Sandra Gonzalez-Palacios, Estefania Toledo, Nadine Khoury, Karla Alejandra Perez, Vicente Martin-Sanchez, Josep A. Tur, Cristina Bouzas
Summary: A 2-year study found that reducing the consumption of ultra-processed foods can decrease greenhouse gas emissions and energy consumption, but increase water use. Therefore, low consumption of ultra-processed foods is beneficial for environmental sustainability.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Nutrition & Dietetics
Carolina Donat-Vargas, Victor Mico, Rodrigo San-Cristobal, Miguel Angel Martinez-Gonzalez, Jordi Salas-Salvado, Dolores Corella, Montserrat Fito, Angel Maria Alonso-Gomez, Julia Waernberg, Jesus Vioque, Dora Romaguera, Jose Lopez-Miranda, Ramon Estruch, Miguel Damas-Fuentes, Jose Lapetra, Luis Serra-Majem, Aurora Bueno-Cavanillas, Josep Antoni Tur, Sergio Cinza-Sanjurjo, Xavier Pinto, Miguel Delgado-Rodriguez, Pilar Matia-Martin, Josep Vidal, Claudia Causso, Emilio Ros, Estefania Toledo, Josep Maria Manzanares, Carolina Ortega-Azorin, Olga Castaner, Patricia Judith Pena-Orihuela, Juan Manuel Zazo, Carlos Munoz Bravo, Diego Martinez-Urbistondo, Alice Chaplin, Rosa Casas, Naomi Cano Ibanez, Lucas Tojal-Sierra, Ana Maria Gomez-Perez, Elena Pascual Roquet-Jalmar, Cristina Mestre, Rocio Barragan, Helmut Schroder, Antonio Garcia-Rios, Inmaculada Candela Garcia, Miguel Ruiz-Canela, Nancy Babio, Mireia Malcampo, Lidia Daimiel, Alfredo Martinez
Summary: Anemia and lower levels of anemia markers are associated with inferior cognitive function, worse executive function, and poorer physical component of quality of life. These effects are particularly pronounced in individuals with diabetes. Dietary iron intake does not influence these outcomes.
Editorial Material
Nutrition & Dietetics
Rosa Casas
Article
Public, Environmental & Occupational Health
Sara Castro-Barquero, Marta Larroya, Fatima Crispi, Ramon Estruch, Ayako Nakaki, Cristina Paules, Ana Maria Ruiz-Leon, Emilio Sacanella, Tania Freitas, Lina Youssef, Leticia Benitez, Irene Casas, Mariona Genero, Silvia Gomez, Francesc Casanovas-Garriga, Eduard Gratacos, Rosa Casas, Francesca Crovetto
Summary: This study aimed to describe dietary nutrient intake and diet quality during pregnancy and evaluate the association between high adherence to the Mediterranean diet and a more adequate intake of micronutrients. The results showed that pregnant women with high adherence to the Mediterranean diet had a lower proportion of inadequate macro and micronutrient intake. They also had a higher intake of protein, monounsaturated fatty acids, fiber, vitamins (B1, B9, C, D), calcium, magnesium, iron, zinc, phosphor, potassium, essential fatty acids, and a-linolenic acid, and a lower intake of a-linoleic acid and trans fatty acids compared to those with low adherence to the Mediterranean diet.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Medicine, General & Internal
Francesca Crovetto, Ayako Nakaki, Angela Arranz, Roger Borras, Kilian Vellve, Cristina Paules, Maria Laura Boutet, Sara Castro-Barquero, Tania Freitas, Rosa Casas, Andres Martin-Asuero, Teresa Oller Guzman, Ivette Morilla, Anabel Martinez-Aran, Alba Camacho, Mireia Pasqual, Montserrat Izquierdo Renau, Oscar J. Pozo, Alex Gomez-Gomez, Ramon Estruch, Eduard Vieta, Fatima Crispi, Eduard Gratacos
Summary: Maternal suboptimal nutrition and high stress levels are associated with adverse fetal and childhood neurodevelopment. Structured interventions based on a Mediterranean diet or mindfulness-based stress reduction during pregnancy significantly improved child neurodevelopmental outcomes at age 2 years in this randomized clinical trial.
Review
Cardiac & Cardiovascular Systems
Dimitrios Tsiachris, Christos-Konstantinos Antoniou, Ioannis Doundoulakis, Panagiota Manolakou, Demetrios Sougiannis, Athanasios Kordalis, Konstantinos A. Gatzoulis, Gian-Battista Chierchia, Carlo de Asmundis, Christodoulos Stefanadis, Konstantinos Tsioufis
Summary: Nowadays, cryoballoon (CB) has become an established alternative to radio frequency (RF) ablation for pulmonary vein isolation (PVI), with the ability to isolate PVs in a single application. In a study on over 1000 consecutive patients, our center optimized the CB PVI procedure. It is expected that future guidelines will recommend CB as the first-line PVI for patients with paroxysmal AF and a class I indication. In a long-term follow-up of the EARLY-AF trial, CB showed a lower incidence of persistent atrial fibrillation compared to anti-arrhythmic drugs.
JOURNAL OF CARDIOVASCULAR DEVELOPMENT AND DISEASE
(2023)
