BRCA1-associated protein inhibits glioma cell proliferation and migration and glioma stem cell self-renewal via the TGF-β/PI3K/AKT/mTOR signalling pathway

SOX3 can promote the malignant behavior of glioblastoma cells

(2018) Jelena Marjanovic Vicentic et al.   CELLULAR ONCOLOGY

EMT Transition States during Tumor Progression and Metastasis

(2018) Ievgenia Pastushenko et al.   TRENDS IN CELL BIOLOGY

BRCA1-Associated Protein Increases Invasiveness of Esophageal Squamous Cell Carcinoma

(2017) Yanjie Zhao et al.   GASTROENTEROLOGY

Crosstalk between M2 macrophages and glioma stem cells

(2017) Leora M. Nusblat et al.   CELLULAR ONCOLOGY

Dual treatment with shikonin and temozolomide reduces glioblastoma tumor growth, migration and glial-to-mesenchymal transition

(2017) Diana Matias et al.   CELLULAR ONCOLOGY

Epidemiology of Brain Tumors

(2016) Katharine A. McNeill   NEUROLOGIC CLINICS

Genome-wide association study of colorectal cancer identifies six new susceptibility loci

(2015) Fredrick R. Schumacher et al.   Nature Communications

High-grade glioma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

(2014) R. Stupp et al.   ANNALS OF ONCOLOGY

Molecular characterizations of glioblastoma, targeted therapy, and clinical results to date

(2014) Jayson I. L. Bastien et al.   CANCER

PI3K and cancer: lessons, challenges and opportunities

(2014) David A. Fruman et al.   NATURE REVIEWS DRUG DISCOVERY

A Two-Stage Association Study Suggests BRAP as a Susceptibility Gene for Schizophrenia

(2014) Fuquan Zhang et al.   PLoS One

The BRCA1-binding protein BRAP2 can act as a cytoplasmic retention factor for nuclear and nuclear envelope-localizing testicular proteins

(2013) Rebecca G. Davies et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Prognostic significance of BRCA1-associated protein 1 in colorectal cancer

(2013) Jianjun Tang et al.   MEDICAL ONCOLOGY

Molecular targets for cancer therapy in the PI3K/AKT/mTOR pathway

(2013) Jiri Polivka et al.   PHARMACOLOGY & THERAPEUTICS

Signaling interplay between transforming growth factor-β receptor and PI3K/AKT pathways in cancer

(2013) Long Zhang et al.   TRENDS IN BIOCHEMICAL SCIENCES

The single nucleotide polymorphisms in BRAP decrease the risk of metabolic syndrome in a Chinese young adult population

(2012) Lijun Wu et al.   Diabetes & Vascular Disease Research

Direct and Indirect Control of Mitogen-activated Protein Kinase Pathway-associated Components, BRAP/IMP E3 Ubiquitin Ligase and CRAF/RAF1 Kinase, by the Deubiquitylating Enzyme USP15

(2012) Sebastian D. Hayes et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

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(2011) Yi-Chu Liao et al.   MOLECULAR MEDICINE

Status of PI3K inhibition and biomarker development in cancer therapeutics

(2009) B. Markman et al.   ANNALS OF ONCOLOGY

The BRCA-1 binding protein BRAP2 is a novel, negative regulator of nuclear import of viral proteins, dependent on phosphorylation flanking the nuclear localization signal

(2009) Alex J. Fulcher et al.   FASEB JOURNAL

SNPs in BRAP associated with risk of myocardial infarction in Asian populations

(2009) Kouichi Ozaki et al.   NATURE GENETICS

Signaling Threshold Regulation by the Ras Effector IMP

(2008) Sharon A. Matheny et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

p21 Ras/Impedes Mitogenic Signal Propagation Regulates Cytokine Production and Migration in CD4 T Cells

(2008) Jan Czyzyk et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

IMP Modulates KSR1-dependent Multivalent Complex Formation to Specify ERK1/2 Pathway Activation and Response Thresholds

(2008) Chiyuan Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glioma Stem Cells: A Midterm Exam

(2008) Charles D. Stiles et al.   NEURON