Gene networks that compensate for crosstalk with crosstalk

Synthetic mixed-signal computation in living cells

(2016) Jacob R. Rubens et al.   Nature Communications

Galactose metabolic genes in yeast respond to a ratio of galactose and glucose

(2015) Renan Escalante-Chong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Using Targeted Chromatin Regulators to Engineer Combinatorial and Spatial Transcriptional Regulation

(2014) Albert J. Keung et al.   CELL

Quantifying Absolute Protein Synthesis Rates Reveals Principles Underlying Allocation of Cellular Resources

(2014) Gene-Wei Li et al.   CELL

Quorum-Sensing Crosstalk-Driven Synthetic Circuits: From Unimodality to Trimodality

(2014) Fuqing Wu et al.   CHEMISTRY & BIOLOGY

Stochasticity of metabolism and growth at the single-cell level

(2014) Daniel J. Kiviet et al.   NATURE

Characterizing bacterial gene circuit dynamics with optically programmed gene expression signals

(2014) Evan J Olson et al.   NATURE METHODS

Coordination of microbial metabolism

(2014) Victor Chubukov et al.   NATURE REVIEWS MICROBIOLOGY

Crosstalk and the evolution of specificity in two-component signaling

(2014) M. A. Rowland et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genomically encoded analog memory with precise in vivo DNA writing in living cell populations

(2014) F. Farzadfard et al.   SCIENCE

An improved Escherichia coli strain to host gene regulatory networks involving both the AraC and LacI inducible transcription factors

(2014) Manjunatha Kogenaru et al.   Journal of Biological Engineering

Design of orthogonal genetic switches based on a crosstalk map of  s, anti- s, and promoters

(2013) V. A. Rhodius et al.   Molecular Systems Biology

Synthetic analog computation in living cells

(2013) Ramiz Daniel et al.   NATURE

The molecular mechanisms and physiological consequences of oxidative stress: lessons from a model bacterium

(2013) James A. Imlay   NATURE REVIEWS MICROBIOLOGY

A modular strategy for engineering orthogonal chimeric RNA transcription regulators

(2013) Melissa K. Takahashi et al.   NUCLEIC ACIDS RESEARCH

Reward-based hypertension control by a synthetic brain-dopamine interface

(2013) K. Rossger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cell-Based Therapeutics: The Next Pillar of Medicine

(2013) M. A. Fischbach et al.   Science Translational Medicine

Transferring a synthetic gene circuit from yeast to mammalian cells

(2013) Dmitry Nevozhay et al.   Nature Communications

Arabidopsis plants perform arithmetic division to prevent starvation at night

(2013) Antonio Scialdone et al.   eLife

Evolution of Two-Component Signal Transduction Systems

(2012) Emily J. Capra et al.   Annual Review of Microbiology

Crosstalk between endogenous and synthetic components - synthetic signaling meets endogenous components

(2012) Kevin J. Morey et al.   Biotechnology Journal

Adaptive Mutations that Prevent Crosstalk Enable the Expansion of Paralogous Signaling Protein Families

(2012) Emily J. Capra et al.   CELL

Direct Oxidation of the [2Fe-2S] Cluster in SoxR Protein by Superoxide

(2012) Mayu Fujikawa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bacterial virulence proteins as tools to rewire kinase pathways in yeast and immune cells

(2012) Ping Wei et al.   NATURE

Programmable single-cell mammalian biocomputers

(2012) Simon Ausländer et al.   NATURE

Genetic programs constructed from layered logic gates in single cells

(2012) Tae Seok Moon et al.   NATURE

Foundations for the design and implementation of synthetic genetic circuits

(2012) Adrian L. Slusarczyk et al.   NATURE REVIEWS GENETICS

AutoBioCAD: Full Biodesign Automation of Genetic Circuits

(2012) Guillermo Rodrigo et al.   ACS Synthetic Biology

An End-to-End Workflow for Engineering of Biological Networks from High-Level Specifications

(2012) Jacob Beal et al.   ACS Synthetic Biology

Negative auto-regulation increases the input dynamic-range of the arabinose system of Escherichia coli

(2011) Daniel Madar et al.   BMC Systems Biology

Crosstalk in Cellular Signaling: Background Noise or the Real Thing?

(2011) Grégory Vert et al.   DEVELOPMENTAL CELL

The SoxRS response of Escherichia coli is directly activated by redox-cycling drugs rather than by superoxide

(2011) Mianzhi Gu et al.   MOLECULAR MICROBIOLOGY

Substrate Profiling of Tobacco Etch Virus Protease Using a Novel Fluorescence-Assisted Whole-Cell Assay

(2011) George Kostallas et al.   PLoS One

Synthetic Biology: Integrated Gene Circuits

(2011) N. Nandagopal et al.   SCIENCE

The Ras-ERK and PI3K-mTOR pathways: cross-talk and compensation

(2011) Michelle C. Mendoza et al.   TRENDS IN BIOCHEMICAL SCIENCES

BglBrick vectors and datasheets: A synthetic biology platform for gene expression

(2011) Taek Lee et al.   Journal of Biological Engineering

Regulation of cross-talk in yeast MAPK signaling pathways

(2010) Haruo Saito   CURRENT OPINION IN MICROBIOLOGY

Five hard truths for synthetic biology

(2010) Roberta Kwok   NATURE

Self-sufficient control of urate homeostasis in mice by a synthetic circuit

(2010) Christian Kemmer et al.   NATURE BIOTECHNOLOGY

Design, construction and characterization of a set of insulated bacterial promoters

(2010) J. H. Davis et al.   NUCLEIC ACIDS RESEARCH

Oscillations by Minimal Bacterial Suicide Circuits Reveal Hidden Facets of Host-Circuit Physiology

(2010) Philippe Marguet et al.   PLoS One

Interdependence of Cell Growth and Gene Expression: Origins and Consequences

(2010) M. Scott et al.   SCIENCE

A Yeast Synthetic Network for In Vivo Assessment of Reverse-Engineering and Modeling Approaches

(2009) Irene Cantone et al.   CELL

Diversity-based, model-guided construction of synthetic gene networks with predicted functions

(2009) Tom Ellis et al.   NATURE BIOTECHNOLOGY

Signaling cross-talk between TGF-β/BMP and other pathways

(2008) Xing Guo et al.   CELL RESEARCH

Membrane Localization of Scaffold Proteins Promotes Graded Signaling in the Yeast MAP Kinase Cascade

(2008) Satoe Takahashi et al.   CURRENT BIOLOGY

Signal integration in bacterial two-component regulatory systems

(2008) A. Y. Mitrophanov et al.   GENES & DEVELOPMENT

Cross-talk suppression between the CpxA-CpxR and EnvZ-OmpR two-component systems inE. coli

(2008) Albert Siryaporn et al.   MOLECULAR MICROBIOLOGY