Programmable single-cell mammalian biocomputers

Molecular diversity—the toolbox for synthetic gene switches and networks

(2011) Wilfried Weber et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

A Synthetic Optogenetic Transcription Device Enhances Blood-Glucose Homeostasis in Mice

(2011) H. Ye et al.   SCIENCE

Multi-Input RNAi-Based Logic Circuit for Identification of Specific Cancer Cells

(2011) Z. Xie et al.   SCIENCE

Synthetic human cell fate regulation by protein-driven RNA switches

(2011) Hirohide Saito et al.   Nature Communications

A designer network coordinating bovine artificial insemination by ovulation-triggered release of implanted sperms

(2010) Christian Kemmer et al.   JOURNAL OF CONTROLLED RELEASE

A tunable dual-promoter integrator for targeting of cancer cells

(2010) Lior Nissim et al.   Molecular Systems Biology

Distributed biological computation with multicellular engineered networks

(2010) Sergi Regot et al.   NATURE

Robust multicellular computing using genetically encoded NOR gates and chemical ‘wires’

(2010) Alvin Tamsir et al.   NATURE

A synchronized quorum of genetic clocks

(2010) Tal Danino et al.   NATURE

Self-sufficient control of urate homeostasis in mice by a synthetic circuit

(2010) Christian Kemmer et al.   NATURE BIOTECHNOLOGY

Rationally designed logic integration of regulatory signals in mammalian cells

(2010) Madeleine Leisner et al.   Nature Nanotechnology

Synthetic biology: applications come of age

(2010) Ahmad S. Khalil et al.   NATURE REVIEWS GENETICS

An engineered mammalian band-pass network

(2010) D. Greber et al.   NUCLEIC ACIDS RESEARCH

Genetic control of mammalian T-cell proliferation with synthetic RNA regulatory systems

(2010) Y. Y. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reprogramming Cellular Behavior with RNA Controllers Responsive to Endogenous Proteins

(2010) S. J. Culler et al.   SCIENCE

Rewiring of Genetic Networks in Response to DNA Damage

(2010) S. Bandyopadhyay et al.   SCIENCE

A tunable synthetic mammalian oscillator

(2009) Marcel Tigges et al.   NATURE

Synthetic translational regulation by an L7Ae–kink-turn RNP switch

(2009) Hirohide Saito et al.   Nature Chemical Biology

Controlling transgene expression in subcutaneous implants using a skin lotion containing the apple metabolite phloretin

(2009) M. Gitzinger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synthetic Gene Networks That Count

(2009) A. E. Friedland et al.   SCIENCE

Higher-Order Cellular Information Processing with Synthetic RNA Devices

(2008) M. N. Win et al.   SCIENCE