Characterizing the effect of multiple Fc glycan attributes on the effector functions and FcγRIIIa receptor binding activity of an IgG1 antibody

Diversity in host clone performance within a Chinese hamster ovary cell line

(2015) Peter M. O'Callaghan et al.   BIOTECHNOLOGY PROGRESS

Biosimilars advancements: Moving on to the future

(2015) Lilian Rumi Tsuruta et al.   BIOTECHNOLOGY PROGRESS

The criticality of high-resolution N-linked carbohydrate assays and detailed characterization of antibody effector function in the context of biosimilar development

(2015) Lowell J Brady et al.   mAbs

Amino acid and glucose metabolism in fed-batch CHO cell culture affects antibody production and glycosylation

(2014) Yuzhou Fan et al.   BIOTECHNOLOGY AND BIOENGINEERING

Evaluating the impact of cell culture process parameters on monoclonal antibody N-glycosylation

(2014) Marija Ivarsson et al.   JOURNAL OF BIOTECHNOLOGY

Development and Application of a Robust N ‐Glycan Profiling Method for Heightened Characterization of Monoclonal Antibodies and Related Glycoproteins

(2014) Tanya Q. Shang et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

IgG Subclasses and Allotypes: From Structure to Effector Functions

(2014) Gestur Vidarsson et al.   Frontiers in Immunology

Separation of nonfucosylated antibodies with immobilized FcγRIII receptors

(2013) Glen R. Bolton et al.   BIOTECHNOLOGY PROGRESS

The sweet tooth of biopharmaceuticals: Importance of recombinant protein glycosylation analysis

(2012) Nico Lingg et al.   Biotechnology Journal

Quantitative evaluation of fucose reducing effects in a humanized antibody on Fcγ receptor binding and antibody-dependent cell-mediated cytotoxicity activities

(2012) Shan Chung et al.   mAbs

Trastuzumab induces antibody-dependent cell-mediated cytotoxicity (ADCC) in HER-2-non-amplified breast cancer cell lines

(2011) D. M. Collins et al.   ANNALS OF ONCOLOGY

Industry and regulatory experience of the glycosylation of monoclonal antibodies

(2011) Erik K. Read et al.   BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY

Glycosylation profiles of therapeutic antibody pharmaceuticals

(2011) Christoph Wacker et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Therapeutic antibodies: Market considerations, disease targets and bioprocessing

(2011) John G. Elvin et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Towards the implementation of quality by design to the production of therapeutic monoclonal antibodies with desired glycosylation patterns

(2010) Ioscani Jimenez del Val et al.   BIOTECHNOLOGY PROGRESS

Dimers and multimers of monoclonal IgG1 exhibit higher in vitro binding affinities to Fcγ receptors

(2010) Yin Luo et al.   mAbs

Role and mechanism of action of complement in regulating T cell immunity

(2010) Jason R. Dunkelberger et al.   MOLECULAR IMMUNOLOGY

Rituximab: Mechanism of Action

(2010) George J. Weiner   SEMINARS IN HEMATOLOGY

Complement and its role in innate and adaptive immune responses

(2009) Jason R Dunkelberger et al.   CELL RESEARCH

Pharmacological significance of glycosylation in therapeutic proteins

(2009) Huijuan Li et al.   CURRENT OPINION IN BIOTECHNOLOGY

Optimal and consistent protein glycosylation in mammalian cell culture

(2009) P. Hossler et al.   GLYCOBIOLOGY

Quality by design for biopharmaceuticals

(2009) Anurag S Rathore et al.   NATURE BIOTECHNOLOGY

Terminal sugars of Fc glycans influence antibody effector functions of IgGs

(2008) T Shantha Raju   CURRENT OPINION IN IMMUNOLOGY

Glycosylation of Recombinant Antibody Therapeutics

(2005) Royston Jefferis   BIOTECHNOLOGY PROGRESS