Pancreatic cancer-educated macrophages protect cancer cells from complement-dependent cytotoxicity by up-regulation of CD59

Cancer statistics, 2019

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CD59: a promising target for tumor immunotherapy

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Chemotherapeutic drug delivery by tumoral extracellular matrix targeting

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Prognostic values of excision repair cross-complementing genes mRNA expression in ovarian cancer patients

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Targeting the IL-6/JAK/STAT3 signalling axis in cancer

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Stromal Modulation Reverses Primary Resistance to Immune Checkpoint Blockade in Pancreatic Cancer

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Diverse Functions of Macrophages in Different Tumor Microenvironments

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Hippo component YAP promotes focal adhesion and tumour aggressiveness via transcriptionally activating THBS1/FAK signalling in breast cancer

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De novo coiled-coil peptides as scaffolds for disrupting protein–protein interactions

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Ovatodiolide suppresses colon tumorigenesis and prevents polarization of M2 tumor-associated macrophages through YAP oncogenic pathways

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Cross-Linking and Bundling of Self-Assembled Protein-Based Polymer Fibrils via Heterodimeric Coiled Coils

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G-protein-coupled receptor kinase 2 in pancreatic cancer: clinicopathologic and prognostic significance

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The membrane complement regulatory protein CD59 promotes tumor growth and predicts poor prognosis in breast cancer

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Atorvastatin (Lipitor) attenuates the effects of aspirin on pancreatic cancerogenesis and the chemotherapeutic efficacy of gemcitabine on pancreatic cancer by promoting M2 polarized tumor associated macrophages

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Pancreatic cancer

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Cytotoxic mechanisms of immunotherapy: Harnessing complement in the action of anti-tumor monoclonal antibodies

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PTX3 Is an Extrinsic Oncosuppressor Regulating Complement-Dependent Inflammation in Cancer

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The immunohistochemical analysis of membrane-bound CD55, CD59 and fluid-phase FH and FH-like complement inhibitors in cancers of ovary and corpus uteri origin

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Role of Complement and Complement Regulatory Proteins in the Complications of Diabetes

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Immunotherapy improves overall survival in pancreatic cancer

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Bispecific antibodies targeting tumor-associated antigens and neutralizing complement regulators increase the efficacy of antibody-based immunotherapy in mice

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The role of intratumoral and systemic IL-6 in breast cancer

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Serum levels of IL-6 and IL-1β can predict the efficacy of gemcitabine in patients with advanced pancreatic cancer

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Pancreatic Cancer-Associated Stellate Cells Promote Differentiation of Myeloid-Derived Suppressor Cells in a STAT3-Dependent Manner

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CD59 is overexpressed in human lung cancer and regulates apoptosis of human lung cancer cells

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Increased Survival in Pancreatic Cancer with nab-Paclitaxel plus Gemcitabine

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SurvExpress: An Online Biomarker Validation Tool and Database for Cancer Gene Expression Data Using Survival Analysis

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Downregulation of membrane complement inhibitors CD55 and CD59 by siRNA sensitises uterine serous carcinoma overexpressing Her2/neu to complement and antibody-dependent cell cytotoxicity in vitro: implications for trastuzumab-based immunotherapy

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Porous silicon nanocarriers for dual targeting tumor associated endothelial cells and macrophages in stroma of orthotopic human pancreatic cancers

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Complement Protein C1q Directs Macrophage Polarization and Limits Inflammasome Activity during the Uptake of Apoptotic Cells

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Stat3/Socs3 Activation by IL-6 Transsignaling Promotes Progression of Pancreatic Intraepithelial Neoplasia and Development of Pancreatic Cancer

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Macrophage Diversity Enhances Tumor Progression and Metastasis

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Effects of IL-6 and AG490 on regulation of Stat3 signaling pathway and invasion of human pancreatic cancer cells in vitro

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A Six-Gene Signature Predicts Survival of Patients with Localized Pancreatic Ductal Adenocarcinoma

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Complement Regulator CD59 Protects Against Atherosclerosis by Restricting the Formation of Complement Membrane Attack Complex

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