Flaviviral NS4b, chameleon and jack-in-the-box roles in viral replication and pathogenesis, and a molecular target for antiviral intervention
Published 2015 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Flaviviral NS4b, chameleon and jack-in-the-box roles in viral replication and pathogenesis, and a molecular target for antiviral intervention
Authors
Keywords
-
Journal
REVIEWS IN MEDICAL VIROLOGY
Volume 25, Issue 4, Pages 205-223
Publisher
Wiley
Online
2015-04-03
DOI
10.1002/rmv.1835
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Interferon-Stimulated Genes: A Complex Web of Host Defenses
- (2014) William M. Schneider et al. Annual Review of Immunology
- SUMOylation proteins in breast cancer
- (2014) Alaa T. Alshareeda et al. BREAST CANCER RESEARCH AND TREATMENT
- SUMO Ubc9 enzyme as a viral target
- (2014) Archana Varadaraj et al. IUBMB LIFE
- A Nuclear Transport Inhibitor That Modulates the Unfolded Protein Response and Provides In Vivo Protection Against Lethal Dengue virus Infection
- (2014) Johanna E. Fraser et al. JOURNAL OF INFECTIOUS DISEASES
- Dimerization of Flavivirus NS4B Protein
- (2014) J. Zou et al. JOURNAL OF VIROLOGY
- Flavivirus RNAi suppression: decoding non-coding RNA
- (2014) Gorben P Pijlman Current Opinion in Virology
- A new paradigm: innate immune sensing of viruses via the unfolded protein response
- (2014) Judith A. Smith Frontiers in Microbiology
- Stress responses in flavivirus-infected cells: activation of unfolded protein response and autophagy
- (2014) Ana-Belén Blázquez et al. Frontiers in Microbiology
- Identification of a new dengue virus inhibitor that targets the viral NS4B protein and restricts genomic RNA replication
- (2013) Koen W.R. van Cleef et al. ANTIVIRAL RESEARCH
- The flavivirus NS1 protein: Molecular and structural biology, immunology, role in pathogenesis and application as a diagnostic biomarker
- (2013) David A. Muller et al. ANTIVIRAL RESEARCH
- Ten years of dengue drug discovery: Progress and prospects
- (2013) Siew Pheng Lim et al. ANTIVIRAL RESEARCH
- Yellow fever vaccine: Comparison of the neurovirulence of new 17D-204 Stamaril™ seed lots and RK 168-73 strain
- (2013) Jean-Claude Moulin et al. BIOLOGICALS
- Innate Immunity to Dengue Virus Infection and Subversion of Antiviral Responses
- (2013) Angela M. Green et al. JOURNAL OF MOLECULAR BIOLOGY
- Role of RNA Interference (RNAi) in Dengue Virus Replication and Identification of NS4B as an RNAi Suppressor
- (2013) P. K. Kakumani et al. JOURNAL OF VIROLOGY
- The Small Molecules AZD0530 and Dasatinib Inhibit Dengue Virus RNA Replication via Fyn Kinase
- (2013) M. de Wispelaere et al. JOURNAL OF VIROLOGY
- Modulation of Hepatitis C Virus Genome Encapsidation by Nonstructural Protein 4B
- (2013) Q. Han et al. JOURNAL OF VIROLOGY
- The global distribution and burden of dengue
- (2013) Samir Bhatt et al. NATURE
- West Nile virus infection and immunity
- (2013) Mehul S. Suthar et al. NATURE REVIEWS MICROBIOLOGY
- Identification of New Protein Interactions between Dengue Fever Virus and Its Hosts, Human and Mosquito
- (2013) Dumrong Mairiang et al. PLoS One
- Proteomic analysis for Type I interferon antagonism of Japanese encephalitis virus NS5 protein
- (2013) Tsuey-Ching Yang et al. PROTEOMICS
- Immunity and immune response, pathology and pathologic changes: progress and challenges in the immunopathology of yellow fever
- (2013) Juarez A. S. Quaresma et al. REVIEWS IN MEDICAL VIROLOGY
- Protein–protein interactions among West Nile non-structural proteins and transmembrane complex formation in mammalian cells
- (2013) Li Yu et al. VIROLOGY
- Diversion of stress granules and P-bodies during viral infection
- (2013) Lucas C. Reineke et al. VIROLOGY
- A hepatitis C virus NS4B inhibitor suppresses viral genome replication by disrupting NS4B’s dimerization/multimerization as well as its interaction with NS5A
- (2013) Moonju Choi et al. VIRUS GENES
- Adaptation of yellow fever virus 17D to Vero cells is associated with mutations in structural and non-structural protein genes
- (2013) David W.C. Beasley et al. VIRUS RESEARCH
- Intervention strategies for emerging viruses: use of antivirals
- (2013) Yannick Debing et al. Current Opinion in Virology
- Japanese encephalitis
- (2013) Sang-Im Yun et al. Human Vaccines & Immunotherapeutics
- Experimental therapies for yellow fever
- (2012) Justin G. Julander ANTIVIRAL RESEARCH
- Characterization of a model of lethal dengue virus 2 infection in C57BL/6 mice deficient in the alpha/beta interferon receptor
- (2012) S. Orozco et al. JOURNAL OF GENERAL VIROLOGY
- Evidence for a Genetic and Physical Interaction between Nonstructural Proteins NS1 and NS4B That Modulates Replication of West Nile Virus
- (2012) S. Youn et al. JOURNAL OF VIROLOGY
- West Nile Virus Infections Suppress Early Viral RNA Synthesis and Avoid Inducing the Cell Stress Granule Response
- (2012) S. C. Courtney et al. JOURNAL OF VIROLOGY
- Herpes Simplex Virus 1 Ubiquitin Ligase ICP0 Interacts with PML Isoform I and Induces Its SUMO-Independent Degradation
- (2012) D. Cuchet-Lourenco et al. JOURNAL OF VIROLOGY
- Mutational analysis of the West Nile virus NS4B protein
- (2012) Jason A. Wicker et al. VIROLOGY
- Virus–host interactomes — antiviral drug discovery
- (2012) Yue Ma-Lauer et al. Current Opinion in Virology
- How Do Viruses Interact with Stress-Associated RNA Granules?
- (2012) Richard E. Lloyd PLoS Pathogens
- DENV Inhibits Type I IFN Production in Infected Cells by Cleaving Human STING
- (2012) Sebastian Aguirre et al. PLoS Pathogens
- Development and characterization of a stable luciferase dengue virus for high-throughput screening
- (2011) Gang Zou et al. ANTIVIRAL RESEARCH
- Narasin, a novel antiviral compound that blocks dengue virus protein expression
- (2011) June Su Yin Low et al. ANTIVIRAL THERAPY
- Flavivirus NS3 and NS5 proteins interaction network: a high-throughput yeast two-hybrid screen
- (2011) Marc Le Breton et al. BMC MICROBIOLOGY
- Estimated global incidence of Japanese encephalitis:
- (2011) Grant Campbell et al. BULLETIN OF THE WORLD HEALTH ORGANIZATION
- Dengue Virus Modulates the Unfolded Protein Response in a Time-dependent Manner
- (2011) José Peña et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cytokine-induced Paracrystals Prolong the Activity of Signal Transducers and Activators of Transcription (STAT) and Provide a Model for the Regulation of Protein Solubility by Small Ubiquitin-like Modifier (SUMO)
- (2011) Mathias Droescher et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Sumoylation-promoted Enterovirus 71 3C Degradation Correlates with a Reduction in Viral Replication and Cell Apoptosis
- (2011) Shu-Chuan Chen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A Single Amino Acid in Nonstructural Protein NS4B Confers Virulence to Dengue Virus in AG129 Mice through Enhancement of Viral RNA Synthesis
- (2011) D. Grant et al. JOURNAL OF VIROLOGY
- Inhibition of Dengue Virus by Targeting Viral NS4B Protein
- (2011) X. Xie et al. JOURNAL OF VIROLOGY
- Uncoupling cis-Acting RNA Elements from Coding Sequences Revealed a Requirement of the N-Terminal Region of Dengue Virus Capsid Protein in Virus Particle Formation
- (2011) M. M. Samsa et al. JOURNAL OF VIROLOGY
- A Physical Interaction Network of Dengue Virus and Human Proteins
- (2011) Sudip Khadka et al. MOLECULAR & CELLULAR PROTEOMICS
- A diverse range of gene products are effectors of the type I interferon antiviral response
- (2011) John W. Schoggins et al. NATURE
- Ago-2-Mediated Slicer Activity Is Essential for Anti-Flaviviral Efficacy of RNAi
- (2011) Shuiping Chen et al. PLoS One
- Combination of α-glucosidase inhibitor and ribavirin for the treatment of dengue virus infection in vitro and in vivo
- (2010) Jinhong Chang et al. ANTIVIRAL RESEARCH
- The Hepatitis C Virus (HCV) NS4B RNA Binding Inhibitor Clemizole Is Highly Synergistic with HCV Protease Inhibitors
- (2010) Shirit Einav et al. JOURNAL OF INFECTIOUS DISEASES
- West Nile Virus Differentially Modulates the Unfolded Protein Response To Facilitate Replication and Immune Evasion
- (2010) R. L. Ambrose et al. JOURNAL OF VIROLOGY
- The SUMO pathway: emerging mechanisms that shape specificity, conjugation and recognition
- (2010) Jaclyn R. Gareau et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- West Nile virus and its emergence in the United States of America
- (2010) Kristy O. Murray et al. VETERINARY RESEARCH
- Novel Imino Sugar Derivatives Demonstrate Potent Antiviral Activity against Flaviviruses
- (2009) J. Chang et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Identification of Inhibitors of Yellow Fever Virus Replication Using a Replicon-Based High-Throughput Assay
- (2009) C. G. Patkar et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Composition and Three-Dimensional Architecture of the Dengue Virus Replication and Assembly Sites
- (2009) Sonja Welsch et al. Cell Host & Microbe
- Identification of a Novel Determinant for Membrane Association in Hepatitis C Virus Nonstructural Protein 4B
- (2009) J. Gouttenoire et al. JOURNAL OF VIROLOGY
- Eukaryotic Stress Granules: The Ins and Outs of Translation
- (2009) J. Ross Buchan et al. MOLECULAR CELL
- STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity
- (2009) Hiroki Ishikawa et al. NATURE
- Targeting the ubiquitin system in cancer therapy
- (2009) Daniela Hoeller et al. NATURE
- Hepatitis C virus NS4B induces unfolded protein response and endoplasmic reticulum overload response-dependent NF-κB activation
- (2009) Shanshan Li et al. VIROLOGY
- The flavivirus polymerase as a target for drug discovery
- (2008) Hélène Malet et al. ANTIVIRAL RESEARCH
- Molecular targets for flavivirus drug discovery
- (2008) Aruna Sampath et al. ANTIVIRAL RESEARCH
- Tomato bushy stunt virus Co-Opts the RNA-Binding Function of a Host Metabolic Enzyme for Viral Genomic RNA Synthesis
- (2008) Robert Yung-Liang Wang et al. Cell Host & Microbe
- Dengue virus regulates type I interferon signalling in a strain-dependent manner in human cell lines
- (2008) I. Umareddy et al. JOURNAL OF GENERAL VIROLOGY
- RNA interference screen for human genes associated with West Nile virus infection
- (2008) Manoj N. Krishnan et al. NATURE
- Modification of intracellular membrane structures for virus replication
- (2008) Sven Miller et al. NATURE REVIEWS MICROBIOLOGY
Become a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get StartedAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started