Gasdermin D-mediated hepatocyte pyroptosis expands inflammatory responses that aggravate acute liver failure by upregulating monocyte chemotactic protein 1/CC chemokine receptor-2 to recruit macrophages

Macrophage migration inhibitory factor plays an essential role in ischemic preconditioning-mediated cardioprotection

(2019) Amanguli Ruze et al.   CLINICAL SCIENCE

The Coming Decade of Cell Death Research: Five Riddles

(2019) Douglas R. Green   CELL

Death Is Coming and the Clot Thickens, as Pyroptosis Feeds the Fire

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Kaempferol protects mice from d-GalN/LPS-induced acute liver failure by regulating the ER stress-Grp78-CHOP signaling pathway

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American Gastroenterological Association Institute Guidelines for the Diagnosis and Management of Acute Liver Failure

(2017) Steven L. Flamm et al.   GASTROENTEROLOGY

Structure insight of GSDMD reveals the basis of GSDMD autoinhibition in cell pyroptosis

(2017) Siyun Kuang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pore-forming activity and structural autoinhibition of the gasdermin family

(2016) Jingjin Ding et al.   NATURE

Hepatitis C Virus Infection of Cultured Human Hepatoma Cells Causes Apoptosis and Pyroptosis in Both Infected and Bystander Cells

(2016) H. M. Kofahi et al.   Scientific Reports

Gasdermin D: the long-awaited executioner of pyroptosis

(2015) Si Ming Man et al.   CELL RESEARCH

Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion

(2015) Wan-ting He et al.   CELL RESEARCH

Receptor interacting protein kinase 1 mediates murine acetaminophen toxicity independent of the necrosome and not through necroptosis

(2015) Lily Dara et al.   HEPATOLOGY

Heatstroke induces liver injury via IL-1β and HMGB1-induced pyroptosis

(2015) Yan Geng et al.   JOURNAL OF HEPATOLOGY

Acute liver failure, multiorgan failure, cerebral oedema, and activation of proangiogenic and antiangiogenic factors in a case of Marburg haemorrhagic fever

(2012) Judith van Paassen et al.   LANCET INFECTIOUS DISEASES

Acute liver failure

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Pyroptosis: host cell death and inflammation

(2009) Tessa Bergsbaken et al.   NATURE REVIEWS MICROBIOLOGY