Palmitoylation of NOD1 and NOD2 is required for bacterial sensing

The heme-regulated inhibitor is a cytosolic sensor of protein misfolding that controls innate immune signaling

(2019) Mena Abdel-Nour et al.   SCIENCE

Protein Lipidation: Occurrence, Mechanisms, Biological Functions, and Enabling Technologies

(2018) Hong Jiang et al.   CHEMICAL REVIEWS

SWISS-MODEL: homology modelling of protein structures and complexes

(2018) Andrew Waterhouse et al.   NUCLEIC ACIDS RESEARCH

Fatty acyl recognition and transfer by an integral membraneS-acyltransferase

(2018) Mitra S. Rana et al.   SCIENCE

Innate Recognition of Intracellular Bacterial Growth Is Driven by the TIFA-Dependent Cytosolic Surveillance Pathway

(2017) Ryan G. Gaudet et al.   Cell Reports

Versatile protein tagging in cells with split fluorescent protein

(2016) Daichi Kamiyama et al.   Nature Communications

Calcium-sensing receptors signal constitutive macropinocytosis and facilitate the uptake of NOD2 ligands in macrophages

(2016) Johnathan Canton et al.   Nature Communications

Innate Immune Pattern Recognition: A Cell Biological Perspective

(2015) Sky W. Brubaker et al.   Annual Review of Immunology

Palmitoleate Reverses High Fat-induced Proinflammatory Macrophage Polarization via AMP-activated Protein Kinase (AMPK)

(2015) Kenny L. Chan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Palmitoylation controls DLK localization, interactions and activity to ensure effective axonal injury signaling

(2015) Sabrina M. Holland et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Immune Receptor NOD1 and Kinase RIP2 Interact with Bacterial Peptidoglycan on Early Endosomes to Promote Autophagy and Inflammatory Signaling

(2014) Aaron T. Irving et al.   Cell Host & Microbe

Endosomes as Platforms for NOD-like Receptor Signaling

(2014) Kevin S. Bonham et al.   Cell Host & Microbe

Blau syndrome polymorphisms in NOD2 identify nucleotide hydrolysis and helical domain 1 as signalling regulators

(2014) Rhiannon Parkhouse et al.   FEBS LETTERS

NOD1 and NOD2: Signaling, Host Defense, and Inflammatory Disease

(2014) Roberta Caruso et al.   IMMUNITY

Mixed Lineage Kinase Domain-like Protein MLKL Causes Necrotic Membrane Disruption upon Phosphorylation by RIP3

(2014) Huayi Wang et al.   MOLECULAR CELL

Endosomes are specialized platforms for bacterial sensing and NOD2 signalling

(2014) Norihiro Nakamura et al.   NATURE

Emerging roles for protein S-palmitoylation in immunity from chemical proteomics

(2013) Jacob S Yount et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Local palmitoylation cycles define activity-regulated postsynaptic subdomains

(2013) Yuko Fukata et al.   JOURNAL OF CELL BIOLOGY

Manipulation of small Rho GTPases is a pathogen-induced process detected by NOD1

(2013) A. Marijke Keestra et al.   NATURE

Detection of Protein Palmitoylation in Cultured Hippocampal Neurons by Immunoprecipitation and Acyl-Biotin Exchange (ABE)

(2013) G. Stefano Brigidi et al.   Jove-Journal of Visualized Experiments

The intermediate filament protein, vimentin, is a regulator of NOD2 activity

(2012) Craig Stevens et al.   GUT

A promiscuous biotin ligase fusion protein identifies proximal and interacting proteins in mammalian cells

(2012) Kyle J. Roux et al.   JOURNAL OF CELL BIOLOGY

RNAi screening identifies mediators of NOD2 signaling: Implications for spatial specificity of MDP recognition

(2012) S. Lipinski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Comet: An open-source MS/MS sequence database search tool

(2012) Jimmy K. Eng et al.   PROTEOMICS

Mutational analysis of human NOD1 and NOD2 NACHT domains reveals different modes of activation

(2011) Birte Zurek et al.   Innate Immunity

DHHC5 Protein Palmitoylates Flotillin-2 and Is Rapidly Degraded on Induction of Neuronal Differentiation in Cultured Cells

(2011) Yi Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Global profiling of dynamic protein palmitoylation

(2011) Brent R Martin et al.   NATURE METHODS

Tumor suppressor Alpha B-crystallin (CRYAB) associates with the cadherin/catenin adherens junction and impairs NPC progression-associated properties

(2011) Z Huang et al.   ONCOGENE

DHHC palmitoyl transferases: substrate interactions and (patho)physiology

(2011) Jennifer Greaves et al.   TRENDS IN BIOCHEMICAL SCIENCES

Large-scale profiling of protein palmitoylation in mammalian cells

(2009) Brent R Martin et al.   NATURE METHODS

ProteoWizard: open source software for rapid proteomics tools development

(2008) Darren Kessner et al.   BIOINFORMATICS

GEF-H1 Mediated Control of NOD1 Dependent NF-κB Activation by Shigella Effectors

(2008) Atsuko Fukazawa et al.   PLoS Pathogens

Quantitative imaging assay for NF-κB nuclear translocation in primary human macrophages

(2007) Mahdad Noursadeghi et al.   JOURNAL OF IMMUNOLOGICAL METHODS