Nicking Endonucleases as Unique Tools for Biotechnology and Gene Engineering

Low-background and visual detection of antibiotic based on target-activated colorimetric split peroxidase DNAzyme coupled with dual nicking enzyme signal amplification

(2018) Xuejun Cui et al.   ANALYTICA CHIMICA ACTA

An innovative paradigm of methods in microRNAs detection: highlighting DNAzymes, the illuminators

(2018) Mojdeh Mahdiannasser et al.   BIOSENSORS & BIOELECTRONICS

A PCR-free colorimetric strategy for visualized assay of telomerase activity

(2018) Tao Yu et al.   TALANTA

Aligner-mediated cleavage-triggered exponential amplification for sensitive detection of nucleic acids

(2018) Wanghua Wu et al.   TALANTA

Enzymatic amplification of oligonucleotides in paper substrates

(2018) Abootaleb Sedighi et al.   TALANTA

A study on endonuclease BspD6I and its stimulus-responsive switching by modified oligonucleotides

(2018) Liudmila A. Abrosimova et al.   PLoS One

Abasic Site-Assisted Inhibition of Nicking Endonuclease Activity for the Sensitive Determination of Uracil DNA Glycosylase

(2017) Jun Ki Ahn et al.   Biotechnology Journal

Efficient modification of λ-DNA substrates for single-molecule studies

(2017) Yoori Kim et al.   Scientific Reports

Peculiarities of the interaction of the restriction endonuclease BspD6I with DNA containing its recognition site

(2016) Liudmila A. Abrosimova et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Validation of the ANSR® for Campylobacter Method for Detection of Thermophilic Campylobacter spp. in Chicken Carcass Rinse and Turkey Sponge Samples

(2016) Ryan Viator et al.   JOURNAL OF AOAC INTERNATIONAL

Biomedical microfluidic devices by using low-cost fabrication techniques: A review

(2016) Vera Faustino et al.   JOURNAL OF BIOMECHANICS

Coupling a DNA-Based Machine with Glucometer Readouts for Amplified Detection of Telomerase Activity in Cancer Cells

(2016) Wenjing Wang et al.   Scientific Reports

Strand displacement amplification for ultrasensitive detection of human pluripotent stem cells

(2015) Wei Wu et al.   ANALYTICA CHIMICA ACTA

A sensitive lateral flow biosensor for Escherichia coli O157:H7 detection based on aptamer mediated strand displacement amplification

(2015) Wei Wu et al.   ANALYTICA CHIMICA ACTA

Chemical-Oxidation Cleavage Triggered Isothermal Exponential Amplification Reaction for Attomole Gene-Specific Methylation Analysis

(2015) Yuzhi Xu et al.   ANALYTICAL CHEMISTRY

Highly sensitive fluorescence assay of DNA methyltransferase activity by methylation-sensitive cleavage-based primer generation exponential isothermal amplification-induced G-quadruplex formation

(2015) Qingwang Xue et al.   BIOSENSORS & BIOELECTRONICS

Single primer-triggered isothermal amplification for double-stranded DNA detection

(2015) Cuiping Ma et al.   CHEMICAL COMMUNICATIONS

Isothermal Amplification of Nucleic Acids

(2015) Yongxi Zhao et al.   CHEMICAL REVIEWS

Genome-Wide Structural Variation Detection by Genome Mapping on Nanochannel Arrays

(2015) A. C. Y. Mak et al.   GENETICS

Aptamers as a novel tool for diagnostics and therapy

(2015) Onat Kadioglu et al.   INVESTIGATIONAL NEW DRUGS

A simple and highly sensitive DNAzyme-based assay for nicotinamide adenine dinucleotide by ligase-mediated inhibition of strand displacement amplification

(2014) Cheng Jiang et al.   ANALYTICA CHIMICA ACTA

Visual and Highly Sensitive Detection of Cancer Cells by a Colorimetric Aptasensor Based on Cell-Triggered Cyclic Enzymatic Signal Amplification

(2014) Xianxia Zhang et al.   ANALYTICAL CHEMISTRY

Target-Triggering Multiple-Cycle Amplification Strategy for Ultrasensitive Detection of Adenosine Based on Surface Plasma Resonance Techniques

(2014) Gui-Hong Yao et al.   ANALYTICAL CHEMISTRY

Ultrasensitive Detection of Transcription Factors Using Transcription-Mediated Isothermally Exponential Amplification-Induced Chemiluminescence

(2014) Fei Ma et al.   ANALYTICAL CHEMISTRY

Engineering nicking enzymes that preferentially nick 5-methylcytosine-modified DNA

(2014) Alice Gutjahr et al.   NUCLEIC ACIDS RESEARCH

Polymerase/nicking enzyme synergetic isothermal quadratic DNA machine and its application for one-step amplified biosensing of lead (II) ions at femtomole level and DNA methyltransferase

(2014) Yongxi Zhao et al.   NPG Asia Materials

Exponential Strand-Displacement Amplification for Detection of MicroRNAs

(2013) Chao Shi et al.   ANALYTICAL CHEMISTRY

Ultrasensitive Detection of Telomerase Activity at the Single-Cell Level

(2013) Li-juan Wang et al.   ANALYTICAL CHEMISTRY

Sensitive detection of methylated DNA using the short linear quencher–fluorophore probe and two-stage isothermal amplification assay

(2013) Guichi Zhu et al.   BIOSENSORS & BIOELECTRONICS

One-step highly sensitive florescence detection of T4 polynucleotide kinase activity and biological small molecules by ligation-nicking coupled reaction-mediated signal amplification

(2013) Feng Chen et al.   BIOSENSORS & BIOELECTRONICS

Detection of lead(II) ions with a DNAzyme and isothermal strand displacement signal amplification

(2013) Wenying Li et al.   BIOSENSORS & BIOELECTRONICS

A methylation-blocked cascade amplification strategy for label-free colorimetric detection of DNA methyltransferase activity

(2013) Yongxi Zhao et al.   BIOSENSORS & BIOELECTRONICS

Label-free colorimetric assay for base excision repair enzyme activity based on nicking enzyme assisted signal amplification

(2013) Xiaojuan Liu et al.   BIOSENSORS & BIOELECTRONICS

A new hybrid signal amplification strategy for ultrasensitive electrochemical detection of DNA based on enzyme-assisted target recycling and DNA supersandwich assemblies

(2013) Ying Chen et al.   CHEMICAL COMMUNICATIONS

Validation of the ANSR® Listeria Method for Detection of Listeria spp. in Environmental Samples

(2013) Michael Wendorf et al.   JOURNAL OF AOAC INTERNATIONAL

Validation of the ANSR™ Salmonella Method for Detection of Salmonella spp. in Selected Foods and Environmental Samples

(2013) Mark Mozola et al.   JOURNAL OF AOAC INTERNATIONAL

Lab in a Tube: Ultrasensitive Detection of MicroRNAs at the Single-Cell Level and in Breast Cancer Patients Using Quadratic Isothermal Amplification

(2013) Ruixue Duan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Site- and strand-specific nicking of DNA by fusion proteins derived from MutH and I-SceI or TALE repeats

(2013) Lilia Gabsalilow et al.   NUCLEIC ACIDS RESEARCH

DNA Fragments Assembly Based on Nicking Enzyme System

(2013) Rui-Yan Wang et al.   PLoS One

Catalytic domain of plasmid pAD1 relaxase TraX defines a group of relaxases related to restriction endonucleases

(2013) M. V. Francia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Highly Sensitive Detection of Protein with Aptamer-Based Target-Triggering Two-Stage Amplification

(2012) Zhen-zhu Zhang et al.   ANALYTICAL CHEMISTRY

Sensitive Detection of Transcription Factors by Isothermal Exponential Amplification-Based Colorimetric Assay

(2012) Yan Zhang et al.   ANALYTICAL CHEMISTRY

Protein Detection Based on Small Molecule-Linked DNA

(2012) Ya Cao et al.   ANALYTICAL CHEMISTRY

Signal amplified strategy based on target-induced strand release coupling cleavage of nicking endonuclease for the ultrasensitive detection of ochratoxin A

(2012) Xu Hun et al.   BIOSENSORS & BIOELECTRONICS

Enzyme-Regulated Activation of DNAzyme: A Novel Strategy for a Label-Free Colorimetric DNA Ligase Assay and Ligase-Based Biosensing

(2012) Kaiyu He et al.   CHEMISTRY-A EUROPEAN JOURNAL

Identifying individual DNA species in a complex mixture by precisely measuring the spacing between nicking restriction enzymes with atomic force microscope

(2012) J. Reed et al.   Journal of the Royal Society Interface

Sequence dependence of isothermal DNA amplification via EXPAR

(2012) Jifeng Qian et al.   NUCLEIC ACIDS RESEARCH

Oligomerization of site-specific nicking endonuclease BspD6I at high protein concentrations

(2012) S. A. Sekerina et al.   RUSSIAN JOURNAL OF BIOORGANIC CHEMISTRY

Label-free genotyping of cytochrome P450 2D6*10 using ligation-mediated strand displacement amplification with DNAzyme-based chemiluminescence detection

(2011) Hong-Qi Wang et al.   ANALYTICA CHIMICA ACTA

Linear nicking endonuclease-mediated strand-displacement DNA amplification

(2011) Aric Joneja et al.   ANALYTICAL BIOCHEMISTRY

Fabrication of a Highly Sensitive Aptasensor for Potassium with a Nicking Endonuclease-Assisted Signal Amplification Strategy

(2011) Xiaoli Zhu et al.   ANALYTICAL CHEMISTRY

Unimolecular Catalytic DNA Biosensor for Amplified Detection ofl-Histidine via an Enzymatic Recycling Cleavage Strategy

(2011) Rong-Mei Kong et al.   ANALYTICAL CHEMISTRY

Sensitive Detection of microRNA with Isothermal Amplification and a Single-Quantum-Dot-Based Nanosensor

(2011) Yan Zhang et al.   ANALYTICAL CHEMISTRY

A lateral flow biosensor for detection of nucleic acids with high sensitivity and selectivity

(2011) Puchang Lie et al.   CHEMICAL COMMUNICATIONS

Aptameric Molecular Switch for Cascade Signal Amplification

(2011) C. Ma et al.   CLINICAL CHEMISTRY

Degenerate sequence recognition by the monomeric restriction enzyme: single mutation converts BcnI into a strand-specific nicking endonuclease

(2011) Georgij Kostiuk et al.   NUCLEIC ACIDS RESEARCH

Sensitive RNA detection by combining three-way junction formation and primer generation-rolling circle amplification

(2011) Taku Murakami et al.   NUCLEIC ACIDS RESEARCH

Fluorescence Aptameric Sensor for Strand Displacement Amplification Detection of Cocaine

(2010) Jing-Lin He et al.   ANALYTICAL CHEMISTRY

Ultrasensitive Detection of microRNAs by Exponential Isothermal Amplification

(2010) Hongxia Jia et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ultrasensitive DNA Detection by Cascade Enzymatic Signal Amplification Based on Afu Flap Endonuclease Coupled with Nicking Endonuclease

(2010) Bingjie Zou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A ligation-independent cloning method using nicking DNA endonuclease

(2010) Jie Yang et al.   BIOTECHNIQUES

Ultrasensitive and selective DNA detection based on nicking endonuclease assisted signal amplification and its application in cancer cell detection

(2010) Sai Bi et al.   CHEMICAL COMMUNICATIONS

Natural and engineered nicking endonucleases--from cleavage mechanism to engineering of strand-specificity

(2010) S.-H. Chan et al.   NUCLEIC ACIDS RESEARCH

Engineering Nt.BtsCI and Nb.BtsCI nicking enzymes and applications in generating long overhangs

(2009) Priscilla Hiu-Mei Too et al.   NUCLEIC ACIDS RESEARCH

Engineering BspQI nicking enzymes and application of N.BspQI in DNA labeling and production of single-strand DNA

(2009) Penghua Zhang et al.   PROTEIN EXPRESSION AND PURIFICATION

Optical Analysis of Hg2+Ions by Oligonucleotide–Gold-Nanoparticle Hybrids and DNA-Based Machines

(2008) Di Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Specific versus Nonspecific Isothermal DNA Amplification through Thermophilic Polymerase and Nicking Enzyme Activities†

(2008) Eric Tan et al.   BIOCHEMISTRY

Engineering Variants of the I-SceI Homing Endonuclease with Strand-specific and Site-specific DNA-nicking Activity

(2008) Yan Niu et al.   JOURNAL OF MOLECULAR BIOLOGY

Enzymatic signal amplification of molecular beacons for sensitive DNA detection

(2008) Jianwei Jeffery Li et al.   NUCLEIC ACIDS RESEARCH

Sensitive isothermal detection of nucleic-acid sequence by primer generation–rolling circle amplification

(2008) Taku Murakami et al.   NUCLEIC ACIDS RESEARCH

A novel sequence-specific RNA quantification method using nicking endonuclease, dual-labeled fluorescent DNA probe, and conformation-interchangeable oligo-DNA

(2008) K. Hosoda et al.   RNA