Neuroinflammation, Gut-Brain Axis and Depression

Exposure to antibiotics in the first 24 months of life and neurocognitive outcomes at 11 years of age

(2019) R. F. Slykerman et al.   PSYCHOPHARMACOLOGY

Gut Microbiota Regulation of Tryptophan Metabolism in Health and Disease

(2018) Allison Agus et al.   Cell Host & Microbe

Beyond the dopamine hypothesis of schizophrenia to three neural networks of psychosis: dopamine, serotonin, and glutamate

(2018) Stephen M. Stahl   CNS SPECTRUMS

A meta-analysis of the use of probiotics to alleviate depressive symptoms

(2018) Qin Xiang Ng et al.   JOURNAL OF AFFECTIVE DISORDERS

The Role of Depressive Subtypes within the Neuroinflammation Hypothesis of Major Depressive Disorder

(2018) Marie Woelfer et al.   NEUROSCIENCE

Prevotella and Klebsiella proportions in fecal microbial communities are potential characteristic parameters for patients with major depressive disorder

(2017) Ping Lin et al.   JOURNAL OF AFFECTIVE DISORDERS

Antidepressants, antimicrobials or both? Gut microbiota dysbiosis in depression and possible implications of the antimicrobial effects of antidepressant drugs for antidepressant effectiveness

(2017) Danielle Macedo et al.   JOURNAL OF AFFECTIVE DISORDERS

Variations in gut microbiota and fecal metabolic phenotype associated with depression by 16S rRNA gene sequencing and LC/MS-based metabolomics

(2017) Meng Yu et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Anti-inflammatory treatment for major depressive disorder: implications for patients with an elevated immune profile and non-responders to standard antidepressant therapy

(2017) Paula Kopschina Feltes et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Expert consensus document: The International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of prebiotics

(2017) Glenn R. Gibson et al.   Nature Reviews Gastroenterology & Hepatology

The role of diet and nutrition on mental health and wellbeing

(2017) Lauren Owen et al.   PROCEEDINGS OF THE NUTRITION SOCIETY

Probiotic treatment reduces depressive-like behaviour in rats independently of diet

(2017) Anders Abildgaard et al.   PSYCHONEUROENDOCRINOLOGY

Feeding the microbiota-gut-brain axis: diet, microbiome, and neuropsychiatry

(2017) Kiran V. Sandhu et al.   Translational Research

From Serotonin to Neuroplasticity: Evolvement of Theories for Major Depressive Disorder

(2017) Bangshan Liu et al.   Frontiers in Cellular Neuroscience

The effects of probiotics on depressive symptoms in humans: a systematic review

(2017) Caroline J. K. Wallace et al.   Annals of General Psychiatry

A continuum of genetic liability for minor and major depression

(2017) E C Corfield et al.   Translational Psychiatry

Blockade of interleukin-6 receptor in the periphery promotes rapid and sustained antidepressant actions: a possible role of gut–microbiota–brain axis

(2017) J-c Zhang et al.   Translational Psychiatry

A combination of probiotics and magnesium orotate attenuate depression in a small SSRI resistant cohort: an intestinal anti-inflammatory response is suggested

(2017) Matthew Bambling et al.   INFLAMMOPHARMACOLOGY

Antibiotics in the first year of life and subsequent neurocognitive outcomes

(2016) Rebecca F. Slykerman et al.   ACTA PAEDIATRICA

Infections and exposure to anti-infective agents and the risk of severe mental disorders: a nationwide study

(2016) O. Köhler et al.   ACTA PSYCHIATRICA SCANDINAVICA

Cognitive impairment by antibiotic-induced gut dysbiosis: Analysis of gut microbiota-brain communication

(2016) Esther E. Fröhlich et al.   BRAIN BEHAVIOR AND IMMUNITY

Similar Fecal Microbiota Signatures in Patients With Diarrhea-Predominant Irritable Bowel Syndrome and Patients With Depression

(2016) Yixuan Liu et al.   Clinical Gastroenterology and Hepatology

Emerging treatment mechanisms for depression: focus on glutamate and synaptic plasticity

(2016) Danielle M. Gerhard et al.   DRUG DISCOVERY TODAY

Possible association of Bifidobacterium and Lactobacillus in the gut microbiota of patients with major depressive disorder

(2016) Emiko Aizawa et al.   JOURNAL OF AFFECTIVE DISORDERS

Transferring the blues: Depression-associated gut microbiota induces neurobehavioural changes in the rat

(2016) John R. Kelly et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Gut microbiome remodeling induces depressive-like behaviors through a pathway mediated by the host’s metabolism

(2016) P Zheng et al.   MOLECULAR PSYCHIATRY

The microbiota in adaptive immune homeostasis and disease

(2016) Kenya Honda et al.   NATURE

Clinical and metabolic response to probiotic administration in patients with major depressive disorder: A randomized, double-blind, placebo-controlled trial

(2016) Ghodarz Akkasheh et al.   NUTRITION

Probiotic supplementation can positively affect anxiety and depressive symptoms: a systematic review of randomized controlled trials

(2016) Meysam Pirbaglou et al.   NUTRITION RESEARCH

The role of glutamatergic, GABA-ergic, and cholinergic receptors in depression and antidepressant-like effect

(2016) Karolina Pytka et al.   Pharmacological Reports

Gut Microbiota, Bacterial Translocation, and Interactions with Diet: Pathophysiological Links between Major Depressive Disorder and Non-Communicable Medical Comorbidities

(2016) Anastasiya Slyepchenko et al.   PSYCHOTHERAPY AND PSYCHOSOMATICS

Regulation of prefrontal cortex myelination by the microbiota

(2016) A E Hoban et al.   Translational Psychiatry

Fecal Microbiota Transplantation and Its Usage in Neuropsychiatric Disorders

(2016) Alper Evrensel et al.   Clinical Psychopharmacology and Neuroscience

So depression is an inflammatory disease, but where does the inflammation come from?

(2016) Michael Berk et al.   BMC Medicine

Inflammation: Depression Fans the Flames and Feasts on the Heat

(2015) Janice K. Kiecolt-Glaser et al.   AMERICAN JOURNAL OF PSYCHIATRY

Adult Hippocampal Neurogenesis Is Regulated by the Microbiome

(2015) Ebere S. Ogbonnaya et al.   BIOLOGICAL PSYCHIATRY

Altered fecal microbiota composition in patients with major depressive disorder

(2015) Haiyin Jiang et al.   BRAIN BEHAVIOR AND IMMUNITY

Antibiotic Exposure and the Risk for Depression, Anxiety, or Psychosis

(2015) Ido Lurie et al.   JOURNAL OF CLINICAL PSYCHIATRY

Administration of Lactobacillus helveticus NS8 improves behavioral, cognitive, and biochemical aberrations caused by chronic restraint stress

(2015) S. Liang et al.   NEUROSCIENCE

The Gut-Brain Axis: The Missing Link in Depression

(2015) Alper Evrensel et al.   Clinical Psychopharmacology and Neuroscience

Inflammatory Depression: A Trifecta of Trouble

(2014) Charles L. Raison   JOURNAL OF CLINICAL PSYCHIATRY

Mental health: A world of depression

(2014) Kerri Smith   NATURE

Medical research: If depression were cancer

(2014) Heidi Ledford   NATURE

Oxidative & nitrosative stress in depression: Why so much stress?

(2014) Steven Moylan et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

A Possible Link between Food and Mood: Dietary Impact on Gut Microbiota and Behavior in BALB/c Mice

(2014) Bettina Pyndt Jørgensen et al.   PLoS One

The Blood-Brain Barrier's Gut Check

(2014) N. Bien-Ly et al.   Science Translational Medicine

Psychobiotics: A Novel Class of Psychotropic

(2013) Timothy G. Dinan et al.   BIOLOGICAL PSYCHIATRY

The association between depressive symptoms, cognitive function, and inflammation in major depression

(2013) Jesper Krogh et al.   BRAIN BEHAVIOR AND IMMUNITY

Altered colonic function and microbiota profile in a mouse model of chronic depression

(2013) A. J. Park et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Feed Your Tregs More Fiber

(2013) J. Bollrath et al.   SCIENCE

Dysregulated relationship of inflammation and oxidative stress in major depression

(2012) B.J. Rawdin et al.   BRAIN BEHAVIOR AND IMMUNITY

Lack of clinical therapeutic benefit of antidepressants is associated overall activation of the inflammatory system

(2012) L.A. Carvalho et al.   JOURNAL OF AFFECTIVE DISORDERS

Evidence for sustained elevation of IL-6 in the CNS as a key contributor of depressive-like phenotypes

(2012) S J Sukoff Rizzo et al.   Translational Psychiatry

Interleukin (IL)-6, tumour necrosis factor alpha (TNF-α) and soluble interleukin-2 receptors (sIL-2R) are elevated in patients with major depressive disorder: A meta-analysis and meta-regression

(2011) Yang Liu et al.   JOURNAL OF AFFECTIVE DISORDERS

Brain?Gut?Microbe Communication in Health and Disease

(2011) Sue Grenham et al.   Frontiers in Physiology

Cytokines mediated inflammation and decreased neurogenesis in animal models of depression

(2010) Cai Song et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Eating ourselves to death (and despair): The contribution of adiposity and inflammation to depression

(2010) Richard C. Shelton et al.   PROGRESS IN NEUROBIOLOGY

A Meta-Analysis of Cytokines in Major Depression

(2009) Yekta Dowlati et al.   BIOLOGICAL PSYCHIATRY

Interaction between genetic polymorphisms and stressful life events in first episode depression

(2009) Jens Drachmann Bukh et al.   JOURNAL OF AFFECTIVE DISORDERS

Major Depressive Disorder

(2008) R.H. Belmaker et al.   NEW ENGLAND JOURNAL OF MEDICINE

From inflammation to sickness and depression: when the immune system subjugates the brain

(2007) Robert Dantzer et al.   NATURE REVIEWS NEUROSCIENCE