aPKCi triggers basal extrusion of luminal mammary epithelial cells by tuning contractility and vinculin localization at cell junctions

Vinculin Force-Sensitive Dynamics at Focal Adhesions Enable Effective Directed Cell Migration

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Force-dependent binding of vinculin to α-catenin regulates cell–cell contact stability and collective cell behavior

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Transition of responsive mechanosensitive elements from focal adhesions to adherens junctions on epithelial differentiation

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Topological defects in epithelia govern cell death and extrusion

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Mechanobiology of collective cell behaviours

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Epithelial cell extrusion: Pathways and pathologies

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Early dissemination seeds metastasis in breast cancer

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Asymmetric division of contractile domains couples cell positioning and fate specification

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Mechanism of early dissemination and metastasis in Her2+ mammary cancer

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Active contractility at E-cadherin junctions and its implications for cell extrusion in cancer

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A strategy for tissue self-organization that is robust to cellular heterogeneity and plasticity

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Defective apical extrusion signaling contributes to aggressive tumor hallmarks

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Pulsatile contractility of actomyosin networks organizes the cellular cortex at lateral cadherin junctions

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Control of MT1-MMP transport by atypical PKC during breast-cancer progression

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Filamin acts as a key regulator in epithelial defence against transformed cells

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Forces in Tissue Morphogenesis and Patterning

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α-catenin, vinculin, and F-actin in strengthening E-cadherin cell–cell adhesions and mechanosensing

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Loss of the Par3 Polarity Protein Promotes Breast Tumorigenesis and Metastasis

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Quantification ofPKCfamily genes in sporadic breast cancer by qRT-PCR: Evidence thatPKCι/λ overexpression is an independent prognostic factor

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Vinculin associates with endothelial VE-cadherin junctions to control force-dependent remodeling

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Outgrowth of single oncogene-expressing cells from suppressive epithelial environments

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Crowding induces live cell extrusion to maintain homeostatic cell numbers in epithelia

(2012) George T. Eisenhoffer et al.   NATURE

Loss of Par3 promotes breast cancer metastasis by compromising cell–cell cohesion

(2012) Bin Xue et al.   NATURE CELL BIOLOGY

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

ECM microenvironment regulates collective migration and local dissemination in normal and malignant mammary epithelium

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The Proto-Oncogene Myc Is Essential for Mammary Stem Cell Function

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Hallmarks of Cancer: The Next Generation

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Vinculin potentiates E-cadherin mechanosensing and is recruited to actin-anchored sites within adherens junctions in a myosin II–dependent manner

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Characterization of the interface between normal and transformed epithelial cells

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An aPKC-Exocyst Complex Controls Paxillin Phosphorylation and Migration through Localised JNK1 Activation

(2009) Carine Rosse et al.   PLOS BIOLOGY

Tensile forces govern germ-layer organization in zebrafish

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