Endurance training remodels skeletal muscle phospholipid composition and increases intrinsic mitochondrial respiration in men with Type 2 diabetes

High-intensity interval, but not endurance training induces muscle fiber type-specific subsarcolemmal lipid droplet size reduction in type 2 diabetic patients

(2018) Han-Chow E Koh et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Cell surface flip-flop of phosphatidylserine is critical for PIEZO1-mediated myotube formation

(2018) Masaki Tsuchiya et al.   Nature Communications

Skeletal muscle phosphatidylcholine and phosphatidylethanolamine respond to exercise and influence insulin sensitivity in men

(2018) Sindre Lee et al.   Scientific Reports

Exercise Response Variations in Skeletal Muscle PCr Recovery Rate and Insulin Sensitivity Relate to Muscle Epigenomic Profiles in Individuals With Type 2 Diabetes

(2018) Natalie A. Stephens et al.   DIABETES CARE

Pioglitazone-induced improvements in insulin sensitivity occur without concomitant changes in muscle mitochondrial function

(2017) Sudip Bajpeyi et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Altered gene expression and repressed markers of autophagy in skeletal muscle of insulin resistant patients with type 2 diabetes

(2017) Andreas Buch Møller et al.   Scientific Reports

Muscle sphingolipids during rest and exercise: a C18:0 signature for insulin resistance in humans

(2016) Bryan C. Bergman et al.   DIABETOLOGIA

Impact of Metformin on Exercise-Induced Metabolic Adaptations to Lower Type 2 Diabetes Risk

(2016) Steven K. Malin et al.   EXERCISE AND SPORT SCIENCES REVIEWS

Skeletal muscle phosphatidylcholine and phosphatidylethanolamine are related to insulin sensitivity and respond to acute exercise in humans

(2016) Sean A. Newsom et al.   JOURNAL OF APPLIED PHYSIOLOGY

EFFECTS OF 12 MONTHS OF CALORIC RESTRICTION ON MUSCLE MITOCHONDRIAL FUNCTION IN HEALTHY INDIVIDUALS

(2016) Lauren Marie Sparks et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Chronological Age Does not InfluenceEx-vivoMitochondrial Respiration and Quality Control in Skeletal Muscle

(2016) Giovanna Distefano et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Active individuals have high mitochondrial content and oxidative markers in their abdominal subcutaneous adipose tissue

(2016) Maria F. Pino et al.   Obesity

TRIB1 Is Regulated Post-Transcriptionally by Proteasomal and Non-Proteasomal Pathways

(2016) Sébastien Soubeyrand et al.   PLoS One

The CDP-Ethanolamine Pathway Regulates Skeletal Muscle Diacylglycerol Content and Mitochondrial Biogenesis without Altering Insulin Sensitivity

(2015) Ahrathy Selathurai et al.   Cell Metabolism

Skeletal Muscle Phospholipid Metabolism Regulates Insulin Sensitivity and Contractile Function

(2015) Katsuhiko Funai et al.   DIABETES

Exercise and Weight Loss Improve Muscle Mitochondrial Respiration, Lipid Partitioning, and Insulin Sensitivity After Gastric Bypass Surgery

(2015) Paul M. Coen et al.   DIABETES

Metabolic Effects of Exercise Training Among Fitness-Nonresponsive Patients With Type 2 Diabetes: The HART-D Study

(2015) Ambarish Pandey et al.   DIABETES CARE

Training status diverges muscle diacylglycerol accumulation during free fatty acid elevation

(2014) Lisa S. Chow et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Characterization and Quantification of Diacylglycerol Species in Biological Extracts after One-Step Derivatization: A Shotgun Lipidomics Approach

(2014) Miao Wang et al.   ANALYTICAL CHEMISTRY

Long–echo time MR spectroscopy for skeletal muscle acetylcarnitine detection

(2014) Lucas Lindeboom et al.   JOURNAL OF CLINICAL INVESTIGATION

Multi-omic integrated networks connect DNA methylation and miRNA with skeletal muscle plasticity to chronic exercise in Type 2 diabetic obesity

(2014) David S. Rowlands et al.   PHYSIOLOGICAL GENOMICS

Metformin Impairs Mitochondrial Function in Skeletal Muscle of Both Lean and Diabetic Rats in a Dose-Dependent Manner

(2014) Bart Wessels et al.   PLoS One

Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool

(2013) Edward Y Chen et al.   BMC BIOINFORMATICS

Cardiolipin remodeling in diabetic heart

(2013) Quan He et al.   CHEMISTRY AND PHYSICS OF LIPIDS

"Deficiency" of Mitochondria in Muscle Does Not Cause Insulin Resistance

(2013) J. O. Holloszy   DIABETES

Nine Months of Combined Training Improves Ex Vivo Skeletal Muscle Metabolism in Individuals With Type 2 Diabetes

(2013) Lauren M. Sparks et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Reduced skeletal muscle oxidative capacity and elevated ceramide but not diacylglycerol content in severe obesity

(2013) P.M. Coen et al.   Obesity

A role for RNA post-transcriptional regulation in satellite cell activation

(2013) Nicholas H Farina et al.   Skeletal Muscle

Prolonged exercise training increases intramuscular lipid content and perilipin 2 expression in type I muscle fibers of patients with type 2 diabetes

(2012) C. S. Shaw et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Skeletal Muscle Triglycerides, Diacylglycerols, and Ceramides in Insulin Resistance: Another Paradox in Endurance-Trained Athletes?

(2011) F. Amati et al.   DIABETES

Effects of weight loss and exercise on insulin resistance, and intramyocellular triacylglycerol, diacylglycerol and ceramide

(2011) J. J. Dubé et al.   DIABETOLOGIA

Mitochondrial lipid oxidation is impaired in cultured myotubes from obese humans

(2011) K E Boyle et al.   INTERNATIONAL JOURNAL OF OBESITY

Skeletal Muscle Mitochondrial Capacity and Insulin Resistance in Type 2 Diabetes

(2011) Sudip Bajpeyi et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Remodeling Lipid Metabolism and Improving Insulin Responsiveness in Human Primary Myotubes

(2011) Lauren M. Sparks et al.   PLoS One

Restoration of Muscle Mitochondrial Function and Metabolic Flexibility in Type 2 Diabetes by Exercise Training Is Paralleled by Increased Myocellular Fat Storage and Improved Insulin Sensitivity

(2009) R. C.R. Meex et al.   DIABETES

Influence of Gender, Obesity, and Muscle Lipase Activity on Intramyocellular Lipids in Sedentary Individuals

(2009) Cedric Moro et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Exercise-induced alterations in intramyocellular lipids and insulin resistance: the athlete's paradox revisited

(2008) John J. Dubé et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Lower Intrinsic ADP-Stimulated Mitochondrial Respiration Underlies In Vivo Mitochondrial Dysfunction in Muscle of Male Type 2 Diabetic Patients

(2008) E. Phielix et al.   DIABETES

Mitochondrial Capacity in Skeletal Muscle Is Not Stimulated by Weight Loss Despite Increases in Insulin Action and Decreases in Intramyocellular Lipid Content

(2008) F. G.S. Toledo et al.   DIABETES

Human skeletal muscle ceramide content is not a major factor in muscle insulin sensitivity

(2008) M. Skovbro et al.   DIABETOLOGIA

Early or advanced stage type 2 diabetes is not accompanied by in vivo skeletal muscle mitochondrial dysfunction

(2008) H M De Feyter et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Membrane lipids: where they are and how they behave

(2008) Gerrit van Meer et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY