Review
Plant Sciences
Zhicheng Jiao, Huan Du, Shu Chen, Wei Huang, Liangfa Ge
Summary: Adapting to the gravitational field is crucial for terrestrial plants to thrive on Earth. The LAZY gene family has been identified as a key player in the early stages of gravity signaling, ensuring proper auxin redistribution for both roots and shoots upon gravistimulation. Research on LAZY genes has significantly advanced our understanding of plant gravitropism and revealed new molecular details of early gravitropism events.
FRONTIERS IN PLANT SCIENCE
(2021)
Review
Biochemistry & Molecular Biology
Nataliia Konstantinova, Barbara Korbei, Christian Luschnig
Summary: Root architecture and growth play a crucial role in crop performance and yield, making it a highly relevant field of research in plant sciences. The root system of Arabidopsis thaliana serves as an ideal model for studying key parameters and molecular players involved in root growth responses to environmental stimuli. This review focuses on the function of PIN-FORMED auxin transport proteins, emphasizing their sorting and polarity control, and aims to integrate the wealth of information available on mechanisms and pathways to enhance understanding of auxin's role in higher plants.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Materials Science, Multidisciplinary
Andras A. Sipos, Peter L. Varkonyi
Summary: This study develops a three-dimensional morphoelastic rod model to investigate the shapes of roots. By simulating root growth on hard soil surfaces with different angles of inclination, the study finds that the model parameters associated with control mechanisms and the angle of inclination determine the root morphology, and the interaction between circumnutation and gravitropism is the main mechanism behind root coiling, waving, and skewing.
JOURNAL OF THE MECHANICS AND PHYSICS OF SOLIDS
(2022)
Article
Biochemistry & Molecular Biology
Feng Zhang, Cuiling Li, Xingzhen Qu, Jiajia Liu, Zipeng Yu, Junxia Wang, Jiayong Zhu, Yongqiang Yu, Zhaojun Ding
Summary: Gravitropism is an essential adaptive response of land plants, and auxin plays a crucial role in this process. This study reveals the novel role of MES17-mediated auxin homeostasis in gravitropic responses and identifies an ARF7-triggered feedback mechanism that reinforces the asymmetric distribution of active auxin, thereby strictly controlling gravitropism in plants.
JOURNAL OF INTEGRATIVE PLANT BIOLOGY
(2022)
Article
Plant Sciences
Ying Li, Jinying Luo, Rong Chen, Yuhong Zhou, Huiyang Yu, Zhuannan Chu, Yongen Lu, Xiaofeng Gu, Shuang Wu, Pengwei Wang, Hanhui Kuang, Bo Ouyang
Summary: A study in Arabidopsis identified the important role of folate in plant root development. The folb2 mutant showed severe defects in primary root development, with impaired root apical meristem and frequent adventitious roots. The mutation in the AtFolB2 gene, involved in folate biosynthesis, resulted in reduced folate content and knockdown lines phenocopied the mutant. Folate was found to promote auxin transport and affect auxin-related proteins and response factors, providing insights into its role in shaping root structure.
Editorial Material
Plant Sciences
Arpita Yadav
Summary: Research found that negative phototropism and positive hydrotropism in Arabidopsis roots are closely associated with the genes MIZ1 and GNOM/MIZ2. Mutations in these genes result in loss of phototropism.
JOURNAL OF EXPERIMENTAL BOTANY
(2023)
Review
Plant Sciences
Huibin Han, Maciek Adamowski, Linlin Qi, Saqer S. Alotaibi, Jiri Friml
Summary: Plants exhibit differential growth responses through the coordination of auxin hormone and PIN auxin exporters during tropisms, which are regulated by environmental stimuli. Auxin gradients promote cell elongation and bending, with auxin feedback playing a crucial role in PIN polarity during bending termination. Interactions between different tropisms are reviewed to enhance understanding of plant adaptive growth in the natural environment.
Article
Plant Sciences
Nicolas Levernier, Olivier Pouliquen, Yoel Forterre
Summary: This article investigates the response mechanism of plants to gravity, proposing a new theory that statoliths act as position sensors rather than gravitational force sensors, and establishing a model to explain plant gravitropism. The model recovers several major features of the gravitropic response of plants and predicts the existence of a gravity-independent memory process associated with PIN turnover, calling for further experimental studies.
FRONTIERS IN PLANT SCIENCE
(2021)
Article
Agronomy
Wenqiang Li, Minjuan Zhang, Lei Qiao, Yunbo Chen, Dapeng Zhang, Xiuqing Jing, Pengfei Gan, Yangbin Huang, Junru Gao, Wenting Liu, Chunhai Shi, Hongchang Cui, Haifeng Li, Kunming Chen
Summary: Gravity plays a role in root system architecture, and the loss of function of the OsPIN2 gene in the rice wavy root 1 (war1) mutant leads to altered root architecture, disrupted auxin transport, decreased amyloplast sedimentation, and impaired ABA signaling. OsPIN2 not only regulates root gravitropism through auxin transport, but also affects seed germination and root development through ABA signaling.
Article
Biology
Chenghui Yang, Dongdong Wang, Chao Zhang, Minghui Ye, Nana Kong, Haoli Ma, Qin Chen
Summary: This study provides comprehensive information on auxin transporter gene families in potato, including their basic parameters, expression patterns, tissue-specificity, subcellular localizations, and transcriptional responses under different stresses. The results suggest that these genes play crucial roles in auxin homeostasis and environmental adaptation.
Review
Plant Sciences
Jakub Hajny, Shutang Tan, Jiri Friml
Summary: The plant hormone auxin has the ability to promote formation of its own directional transport routes, which involves coordinated polarization of individual cells. This mechanism plays a crucial role in plant development.
CURRENT OPINION IN PLANT BIOLOGY
(2022)
Article
Plant Sciences
Tom J. Fisher, Eduardo Flores-Sandoval, John P. Alvarez, John L. Bowman
Summary: This study provides the first characterization of PIN proteins in the liverwort Marchantia polymorpha. The MpPIN1 protein is localized in the plasma membrane and plays essential roles in plant growth and development, including the regulation of leaf and flower development. These findings contribute to our understanding of signal transduction and directional growth in plant development.
Article
Biochemistry & Molecular Biology
Shiv Mani Dubey, Soeun Han, Nathan Stutzman, Michael J. Prigge, Eva Medvecka, Matthieu Pierre Platre, Wolfgang Busch, Matyas Fendrych, Mark Estelle
Summary: The phytohormone auxin triggers root growth inhibition within seconds via a non-transcriptional pathway. The AFB1 protein plays a crucial role in this rapid response, and its N-terminal region, including the F-box domain and residues contributing to auxin binding, is essential for its specific function. A substitution of the N-terminal region of AFB1 disrupts its cytoplasmic localization and activity in rapid root growth inhibition. Moreover, AFB1 is involved in calcium influx triggered by auxin and negatively regulates lateral root formation and transcription of auxin-induced genes.
Article
Biochemistry & Molecular Biology
Houjun Zhou, Haiman Ge, Jiahong Chen, Xueqin Li, Lei Yang, Hongxia Zhang, Yuan Wang
Summary: This study reveals the mechanism by which high concentration of SA affects gravitropic root growth and root hair development in plants. The regulation of PIN2 gene transcription and endocytosis of PIN2 protein are involved in this process. Exogenous SA application inhibits gravitropic root growth and root hair development by affecting auxin accumulation and PIN2 distribution.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Biochemistry & Molecular Biology
Silvia Melina Velasquez, Xiaoyuan Guo, Marcal Gallemi, Bibek Aryal, Peter Venhuizen, Elke Barbez, Kai Alexander Duenser, Martin Darino, Ales Pencik, Ondrej Novak, Maria Kalyna, Gregory Mouille, Eva Benkova, Rishikesh Bhalerao, Jozef Mravec, Jurgen Kleine-Vehn
Summary: Auxin plays a crucial role in controlling molecular complexity of cell wall hemicellulose and the rates of differential growth in plants.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Cell Biology
Jiri Friml
Summary: Auxin has always been a prominent topic in plant physiology and development research. This article presents 14 key points in the understanding of auxin, highlighting its unique features among phytohormones and the persistent mysteries and controversies surrounding it. The unexpected discoveries in rapid auxin responses and growth regulation, along with advancements in technology, pave the way for an exciting new era in auxin research.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY
(2022)
Review
Plant Sciences
Jakub Hajny, Shutang Tan, Jiri Friml
Summary: The plant hormone auxin has the ability to promote formation of its own directional transport routes, which involves coordinated polarization of individual cells. This mechanism plays a crucial role in plant development.
CURRENT OPINION IN PLANT BIOLOGY
(2022)
Article
Plant Sciences
Ren Wang, Ellie Himschoot, Matteo Grenzi, Jian Chen, Alaeddine Safi, Melanie Krebs, Karin Schumacher, Moritz K. Nowack, Wolfgang Moeder, Keiko Yoshioka, Daniel Van Damme, Ive De Smet, Danny Geelen, Tom Beeckman, Jiri Friml, Alex Costa, Steffen Vanneste
Summary: This study evaluates the effects of different auxin analogs on the accumulation of PIN proteins in BFA bodies and their ability to induce Ca2+ responses. The results show that not all auxin analogs can elicit Ca2+ responses and their ability to do so partially correlates with their inhibition of BFA body formation.
JOURNAL OF EXPERIMENTAL BOTANY
(2022)
Review
Biochemistry & Molecular Biology
Zipeng Yu, Feng Zhang, Jiri Friml, Zhaojun Ding
Summary: Auxin, one of the most widely studied phytohormones, has been a hot topic in plant biology. The advances in understanding auxin signaling, including perception, rapid responses, transcriptional and non-transcriptional branches, and epigenetic regulation, have been highlighted. Feedback inhibition mechanisms and non-canonical signaling have also been explored. Further identification of auxin signaling components and their regulation will deepen our understanding of how auxin signals regulate plant growth and development at the cellular level.
JOURNAL OF INTEGRATIVE PLANT BIOLOGY
(2022)
Article
Plant Sciences
Ivan Kashkan, Monika Hrtyan, Katarzyna Retzer, Jana Humpolickova, Aswathy Jayasree, Roberta Filepova, Zuzana Vondrakova, Sibu Simon, Debbie Rombaut, Thomas B. Jacobs, Mikko J. Frilander, Jan Hejatko, Jiri Friml, Jan Petrasek, Kamil Ruzicka
Summary: Advanced transcriptome sequencing has shown that alternative splicing of eukaryotic genes plays a crucial role in plant hormone transport. Specifically, in the model plant Arabidopsis thaliana, alternative splicing of the PIN7 gene affects the transport of the plant hormone auxin, influencing root bending in seedlings and auxin-mediated responses.
Review
Plant Sciences
Lanxin Li, Michelle Gallei, Jiri Friml
Summary: In this review, recent unexpected insights into the mechanisms underlying auxin regulation of growth are discussed, challenging existing models. The divergent mechanisms of apoplastic pH regulation in shoots and roots are focused on, revisiting the classical Acid Growth Theory and discussing coordinated involvement of multiple auxin signaling pathways.
TRENDS IN PLANT SCIENCE
(2022)
Article
Biochemistry & Molecular Biology
Dana A. Dahhan, Gregory D. Reynolds, Jessica J. Cardenas, Dominique Eeckhout, Alexander Johnson, Klaas Yperman, Walter A. Kaufmann, Nou Vang, Xu Yan, Inhwan Hwang, Antje Heese, Geert De Jaeger, Jiri Friml, Daniel Van Damme, Jianwei Pan, Sebastian Y. Bednarek
Summary: In this study, mass spectrometry was used to analyze the proteome of Arabidopsis suspension-cultured cell clathrin-coated vesicles (CCVs). The study identified evolutionarily conserved and plant-specific factors associated with CCVs. Notably, the AP-4 complex was found to be abundantly present in the CCV proteome.
Article
Biochemistry & Molecular Biology
Veronika Bilanovicova, Nikola Rydza, Lilla Koczka, Martin Hess, Elena Feraru, Jiri Friml, Tomasz Nodzynski
Summary: Plant development relies on the redistribution of the hormone auxin between cells, which is facilitated by PIN1 proteins located on the plasma membrane. The hydrophilic loop of PIN1 is intrinsically disordered and plays a crucial role in subcellular trafficking and vasculature formation.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Multidisciplinary Sciences
Zhisen Yang, Jing Xia, Jingjing Hong, Chenxi Zhang, Hong Wei, Wei Ying, Chunqiao Sun, Lianghanxiao Sun, Yanbo Mao, Yongxiang Gao, Shutang Tan, Jiri Friml, Dianfan Li, Xin Liu, Linfeng Sun
Summary: This study reports different conformational structures of Arabidopsis thaliana PIN1, revealing the substrate recognition and transport mechanisms of PIN proteins. These findings are of great significance for understanding the directional auxin transport process in plant development.
Article
Multidisciplinary Sciences
Yalu Wang, Zhi Yuan, Jinyi Wang, Huixin Xiao, Lu Wan, Lanxin Li, Yan Guo, Zhizhong Gong, Jiri Friml, Jing Zhang
Summary: Plants adapt their root systems to low NO3- conditions by regulating auxin and NO3- levels, with NRT2.1 directly interacting with PIN7 to modulate auxin transport and root growth in response to NO3- limitation.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2023)
Review
Plant Sciences
Lukas Fiedler, Jiri Friml
Summary: Plants have developed multiple receptor systems and signal transduction cascades to respond to the hormone auxin. However, there is still a lack of comprehensive understanding of the various mechanisms involved in auxin signaling. The rapid and slow effects of auxins on plant physiology and development have been a historical controversy in the field. Recent progress has shed light on these unknowns and may have broader implications beyond auxin signaling.
CURRENT OPINION IN PLANT BIOLOGY
(2023)
Letter
Biochemistry & Molecular Biology
Huihuang Chen, Lanxin Li, Minxia Zou, Linlin Qi, Jiri Friml
Review
Plant Sciences
Linlin Qi, Jiri Friml
Summary: cAMP is a versatile second messenger in mammalian signaling pathways, but its role in plants is not well understood. Recent research has discovered that TIR1/AFB auxin receptors in plants have adenylate cyclase activity and are important for auxin signaling. This article summarizes the established cAMP signaling pathways in mammalian cells, discusses the turbulent history of plant cAMP research, and highlights the major progress and unresolved questions. The current paradigm of auxin signaling is also briefly reviewed to provide background for the discussion on the AC activity of TIR1/AFB auxin receptors and its potential role in transcriptional auxin signaling, as well as the impact of these discoveries on plant cAMP research in general.
Article
Biochemistry & Molecular Biology
Zailong Tian, Yuzhou Zhang, Liping Zhu, Bin Jiang, Huiqin Wang, Ruxi Gao, Jiri Friml, Guanghui Xiao
Summary: Strigolactones (SLs) positively regulate the development of cotton fiber cells by promoting cell elongation and cell wall thickness through the biosynthesis of very long-chain fatty acids (VLCFAs) and cellulose. Transcription factors are involved in the hierarchical regulation of GA-SL crosstalk, and SLs activate downstream genes involved in VLCFA and cellulose biosynthesis.
