Imaging neuromodulators with high spatiotemporal resolution using genetically encoded indicators

Systemic AAV vectors for widespread and targeted gene delivery in rodents

(2019) Rosemary C. Challis et al.   Nature Protocols

Dorsal Striatum Dopamine Levels Fluctuate Across the Sleep–Wake Cycle and Respond to Salient Stimuli in Mice

(2019) Hui Dong et al.   Frontiers in Neuroscience

A Genetically Encoded Fluorescent Sensor for Rapid and Specific In Vivo Detection of Norepinephrine

(2019) Jiesi Feng et al.   NEURON

High-performance calcium sensors for imaging activity in neuronal populations and microcompartments

(2019) Hod Dana et al.   NATURE METHODS

Bright and photostable chemigenetic indicators for extended in vivo voltage imaging

(2019) Ahmed S. Abdelfattah et al.   SCIENCE

Population imaging of neural activity in awake behaving mice

(2019) Kiryl D. Piatkevich et al.   NATURE

A Genetically Encoded Fluorescent Sensor Enables Rapid and Specific Detection of Dopamine in Flies, Fish, and Mice

(2018) Fangmiao Sun et al.   CELL

A genetically encoded fluorescent acetylcholine indicator for in vitro and in vivo studies

(2018) Miao Jing et al.   NATURE BIOTECHNOLOGY

Nontoxic, double-deletion-mutant rabies viral vectors for retrograde targeting of projection neurons

(2018) Soumya Chatterjee et al.   NATURE NEUROSCIENCE

Ultrafast neuronal imaging of dopamine dynamics with designed genetically encoded sensors

(2018) Tommaso Patriarchi et al.   SCIENCE

In vivo measurement of afferent activity with axon-specific calcium imaging

(2018) Gerard Joey Broussard et al.   NATURE NEUROSCIENCE

An open-source control system for in vivo fluorescence measurements from deep-brain structures

(2018) Scott F. Owen et al.   JOURNAL OF NEUROSCIENCE METHODS

A Neural Circuit Mechanism for Encoding Aversive Stimuli in the Mesolimbic Dopamine System

(2018) Johannes W. de Jong et al.   NEURON

Dopamine neurons projecting to medial shell of the nucleus accumbens drive heroin reinforcement

(2018) Julie Corre et al.   eLife

Temporally precise labeling and control of neuromodulatory circuits in the mammalian brain

(2017) Dongmin Lee et al.   NATURE METHODS

Engineered AAVs for efficient noninvasive gene delivery to the central and peripheral nervous systems

(2017) Ken Y Chan et al.   NATURE NEUROSCIENCE

Dorsal Raphe Dopamine Neurons Modulate Arousal and Promote Wakefulness by Salient Stimuli

(2017) Jounhong Ryan Cho et al.   NEURON

Opposite initialization to novel cues in dopamine signaling in ventral and posterior striatum in mice

(2017) William Menegas et al.   eLife

Simultaneous fast measurement of circuit dynamics at multiple sites across the mammalian brain

(2016) Christina K Kim et al.   NATURE METHODS

A Designer AAV Variant Permits Efficient Retrograde Access to Projection Neurons

(2016) D. Gowanlock R. Tervo et al.   NEURON

Sensitive red protein calcium indicators for imaging neural activity

(2016) Hod Dana et al.   eLife

A review of the effects of FSCV and microdialysis measurements on dopamine release in the surrounding tissue

(2015) Andrea Jaquins-Gerstl et al.   ANALYST

Electrochemical Analysis of Neurotransmitters

(2015) Elizabeth S. Bucher et al.   Annual Review of Analytical Chemistry

Intact-Brain Analyses Reveal Distinct Information Carried by SNc Dopamine Subcircuits

(2015) Talia N. Lerner et al.   CELL

Functional Connectome Analysis of Dopamine Neuron Glutamatergic Connections in Forebrain Regions

(2015) S. Mingote et al.   JOURNAL OF NEUROSCIENCE

Neuroanatomy goes viral!

(2015) Jonathan J. Nassi et al.   Frontiers in Neuroanatomy

Natural Neural Projection Dynamics Underlying Social Behavior

(2014) Lisa A. Gunaydin et al.   CELL

The Timing of Dopamine- and Noradrenaline-Mediated Transmission Reflects Underlying Differences in the Extent of Spillover and Pooling

(2014) N. A. Courtney et al.   JOURNAL OF NEUROSCIENCE

Spatial encoding of cyclic AMP signaling specificity by GPCR endocytosis

(2014) Nikoleta G Tsvetanova et al.   Nature Chemical Biology

Independent optical excitation of distinct neural populations

(2014) Nathan C Klapoetke et al.   NATURE METHODS

Cell-based reporters reveal in vivo dynamics of dopamine and norepinephrine release in murine cortex

(2014) Arnaud Muller et al.   NATURE METHODS

Removable cranial windows for long-term imaging in awake mice

(2014) Glenn J Goldey et al.   Nature Protocols

Local control of striatal dopamine release

(2014) Roger Cachope et al.   Frontiers in Behavioral Neuroscience

Molecular signatures of G-protein-coupled receptors

(2013) A. J. Venkatakrishnan et al.   NATURE

Ultrasensitive fluorescent proteins for imaging neuronal activity

(2013) Tsai-Wen Chen et al.   NATURE

Conformational biosensors reveal GPCR signalling from endosomes

(2013) Roshanak Irannejad et al.   NATURE

An optimized fluorescent probe for visualizing glutamate neurotransmission

(2013) Jonathan S Marvin et al.   NATURE METHODS

Analysis of Transduction Efficiency, Tropism and Axonal Transport of AAV Serotypes 1, 2, 5, 6, 8 and 9 in the Mouse Brain

(2013) Dominik F. Aschauer et al.   PLoS One

High-performance execution of psychophysical tasks with complex visual stimuli in MATLAB

(2012) Wael F. Asaad et al.   JOURNAL OF NEUROPHYSIOLOGY

Dopaminergic Modulation of Synaptic Transmission in Cortex and Striatum

(2012) Nicolas X. Tritsch et al.   NEURON

Neuromodulation of Brain States

(2012) Seung-Hee Lee et al.   NEURON

Neuromodulation of Neuronal Circuits: Back to the Future

(2012) Eve Marder   NEURON

Universal Real-Time PCR for the Detection and Quantification of Adeno-Associated Virus Serotype 2-Derived Inverted Terminal Repeat Sequences

(2012) Christine Aurnhammer et al.   Human Gene Therapy Methods

In vivobrain microdialysis: advances in neuropsychopharmacology and drug discovery

(2011) Altaf S Darvesh et al.   Expert Opinion on Drug Discovery

In vivo comparison of norepinephrine and dopamine release in rat brain by simultaneous measurements with fast-scan cyclic voltammetry

(2011) Jinwoo Park et al.   JOURNAL OF NEUROCHEMISTRY

Crystal structure of the β2 adrenergic receptor–Gs protein complex

(2011) Søren G. F. Rasmussen et al.   NATURE

Construction of implantable optical fibers for long-term optogenetic manipulation of neural circuits

(2011) Dennis R Sparta et al.   Nature Protocols

A Cre-Dependent, Anterograde Transsynaptic Viral Tracer for Mapping Output Pathways of Genetically Marked Neurons

(2011) Liching Lo et al.   NEURON

Shaping the synaptic signal: molecular mobility inside and outside the cleft

(2011) Dmitri A. Rusakov et al.   TRENDS IN NEUROSCIENCES

Illuminating Insights into Firefly Luciferase and Other Bioluminescent Reporters Used in Chemical Biology

(2010) Natasha Thorne et al.   CHEMISTRY & BIOLOGY

Imaging neural activity in worms, flies and mice with improved GCaMP calcium indicators

(2009) Lin Tian et al.   NATURE METHODS

NS21: Re-defined and modified supplement B27 for neuronal cultures

(2008) Yucui Chen et al.   JOURNAL OF NEUROSCIENCE METHODS

In Vitro and In Vivo Gene Therapy Vector Evolution via Multispecies Interbreeding and Retargeting of Adeno-Associated Viruses

(2008) D. Grimm et al.   JOURNAL OF VIROLOGY