Fibroblastic reticular cells enhance T cell metabolism and survival via epigenetic remodeling

Fibroblastic reticular cells at the nexus of innate and adaptive immune responses

(2019) Christian Perez‐Shibayama et al.   IMMUNOLOGICAL REVIEWS

Single-Cell RNA Sequencing of Lymph Node Stromal Cells Reveals Niche-Associated Heterogeneity

(2018) Lauren B. Rodda et al.   IMMUNITY

Stromal cell networks coordinate immune response generation and maintenance

(2018) Yannick O. Alexandre et al.   IMMUNOLOGICAL REVIEWS

Plasma cell output from germinal centers is regulated by signals from Tfh and stromal cells

(2018) Yang Zhang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Identification of a new subset of lymph node stromal cells involved in regulating plasma cell homeostasis

(2018) Hsin-Ying Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The human lymph node microenvironment unilaterally regulates T-cell activation and differentiation

(2018) Konstantin Knoblich et al.   PLOS BIOLOGY

Polycomb Repressive Complex 2-Mediated Chromatin Repression Guides Effector CD8 + T Cell Terminal Differentiation and Loss of Multipotency

(2017) Simon M. Gray et al.   IMMUNITY

Cutting Edge: Chromatin Accessibility Programs CD8 T Cell Memory

(2017) Christopher D. Scharer et al.   JOURNAL OF IMMUNOLOGY

Survival of tissue-resident memory T cells requires exogenous lipid uptake and metabolism

(2017) Youdong Pan et al.   NATURE

Fibroblastic reticular cells of the lymphoid tissues modulate T cell activation threshold during homeostasis via hyperactive cyclooxygenase-2/prostaglandin E2 axis

(2017) Miao Yu et al.   Scientific Reports

Dynamic Changes in Chromatin Accessibility Occur in CD8 + T Cells Responding to Viral Infection

(2016) James P. Scott-Browne et al.   IMMUNITY

S-2-hydroxyglutarate regulates CD8+ T-lymphocyte fate

(2016) Petros A. Tyrakis et al.   NATURE

Lineage-specific and single-cell chromatin accessibility charts human hematopoiesis and leukemia evolution

(2016) M Ryan Corces et al.   NATURE GENETICS

BACH2 regulates CD8+ T cell differentiation by controlling access of AP-1 factors to enhancers

(2016) Rahul Roychoudhuri et al.   NATURE IMMUNOLOGY

The epigenetic landscape of T cell exhaustion

(2016) D. R. Sen et al.   SCIENCE

T cell metabolism drives immunity

(2015) Michael D. Buck et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Fibroblastic Reticular Cells: Organization and Regulation of the T Lymphocyte Life Cycle

(2015) Flavian D. Brown et al.   JOURNAL OF IMMUNOLOGY

IL-6 as a keystone cytokine in health and disease

(2015) Christopher A Hunter et al.   NATURE IMMUNOLOGY

Stromal infrastructure of the lymph node and coordination of immunity

(2015) Jonathan E. Chang et al.   TRENDS IN IMMUNOLOGY

A Critical Role of IL-21-Induced BATF in Sustaining CD8-T-Cell-Mediated Chronic Viral Control

(2015) Gang Xin et al.   Cell Reports

The Molecular Signatures Database Hallmark Gene Set Collection

(2015) Arthur Liberzon et al.   Cell Systems

Dendritic cells control fibroblastic reticular network tension and lymph node expansion

(2014) Sophie E. Acton et al.   NATURE

The CLEC-2–podoplanin axis controls the contractility of fibroblastic reticular cells and lymph node microarchitecture

(2014) Jillian L Astarita et al.   NATURE IMMUNOLOGY

B cell homeostasis and follicle confines are governed by fibroblastic reticular cells

(2014) Viviana Cremasco et al.   NATURE IMMUNOLOGY

The transcription factor BATF operates as an essential differentiation checkpoint in early effector CD8+ T cells

(2014) Makoto Kurachi et al.   NATURE IMMUNOLOGY

Fibroblastic reticular cells of the lymph node are required for retention of resting but not activated CD8+ T cells

(2014) A. E. Denton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metabolic Regulation of T Lymphocytes

(2013) Nancie J. MacIver et al.   Annual Review of Immunology

Posttranscriptional Control of T Cell Effector Function by Aerobic Glycolysis

(2013) Chih-Hao Chang et al.   CELL

Interleukin-6 limits influenza-induced inflammation and protects against fatal lung pathology

(2013) Sarah N. Lauder et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position

(2013) Jason D Buenrostro et al.   NATURE METHODS

Cooperativity Between CD8+ T Cells, Non-Neutralizing Antibodies, and Alveolar Macrophages Is Important for Heterosubtypic Influenza Virus Immunity

(2013) Brian J. Laidlaw et al.   PLoS Pathogens

Stromal and hematopoietic cells in secondary lymphoid organs: partners in immunity

(2012) Deepali Malhotra et al.   IMMUNOLOGICAL REVIEWS

PDK1 regulation of mTOR and hypoxia-inducible factor 1 integrate metabolism and migration of CD8+T cells

(2012) David K. Finlay et al.   JOURNAL OF EXPERIMENTAL MEDICINE

An integrated encyclopedia of DNA elements in the human genome

(2012)   NATURE

Transcriptional profiling of stroma from inflamed and resting lymph nodes defines immunological hallmarks

(2012) Deepali Malhotra et al.   NATURE IMMUNOLOGY

Stromal Cell–Immune Cell Interactions

(2011) Ramon Roozendaal et al.   Annual Review of Immunology

The Transcription Factor Myc Controls Metabolic Reprogramming upon T Lymphocyte Activation

(2011) Ruoning Wang et al.   IMMUNITY

Mitochondrial Respiratory Capacity Is a Critical Regulator of CD8+ T Cell Memory Development

(2011) Gerritje J.W. van der Windt et al.   IMMUNITY

Guiding blind T cells and dendritic cells: A closer look at fibroblastic reticular cells found within lymph node T zones

(2011) Sanjiv A. Luther et al.   IMMUNOLOGY LETTERS

Regulated release of nitric oxide by nonhematopoietic stroma controls expansion of the activated T cell pool in lymph nodes

(2011) Veronika Lukacs-Kornek et al.   NATURE IMMUNOLOGY

Fibroblastic Reticular Cells From Lymph Nodes Attenuate T Cell Expansion by Producing Nitric Oxide

(2011) Stefanie Siegert et al.   PLoS One

Regulation of T Cell Priming by Lymphoid Stroma

(2011) Omar Khan et al.   PLoS One

Reproducible Isolation of Lymph Node Stromal Cells Reveals Site-Dependent Differences in Fibroblastic Reticular Cells

(2011) Anne L. Fletcher et al.   Frontiers in Immunology

Anti-apoptosis and cell survival: A review

(2010) Liam Portt et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Immobilized Chemokine Fields and Soluble Chemokine Gradients Cooperatively Shape Migration Patterns of Dendritic Cells

(2010) Kathrin Schumann et al.   IMMUNITY

Qualitatively Different Memory CD8+ T Cells Are Generated after Lymphocytic Choriomeningitis Virus and Influenza Virus Infections

(2010) S. N. Mueller et al.   JOURNAL OF IMMUNOLOGY

Antigen-induced Erk1/2 activation regulates Ets-1-mediated sensitization of CD8+ T cells for IL-12 responses

(2009) Qingsheng Li et al.   JOURNAL OF LEUKOCYTE BIOLOGY