Isoliquiritigenin Inhibits Ovarian Cancer Metastasis by Reversing Epithelial-to-Mesenchymal Transition

Mechanisms underlying isoliquiritigenin-induced apoptosis and cell cycle arrest via ROS-mediated MAPK/STAT3/NF-κB pathways in human hepatocellular carcinoma cells

(2019) Jia-Ru Wang et al.   DRUG DEVELOPMENT RESEARCH

Effects of isoliquiritigenin on ovarian cancer cells

(2018) Nan Li et al.   OncoTargets and Therapy

Isoliquiritigenin inhibits cell proliferation and migration through the PI3K/AKT signaling pathway in A549 lung cancer cells

(2018) Tao Tian et al.   Oncology Letters

Suppression of lung cancer progression by isoliquiritigenin through its metabolite 2, 4, 2’, 4’-Tetrahydroxychalcone

(2018) Changliang Chen et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Isoliquiritigenin Induces Autophagy and Inhibits Ovarian Cancer Cell Growth

(2017) Hsin-Yuan Chen et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The licorice dietary component isoliquiritigenin chemosensitizes human uterine sarcoma cells to doxorubicin and inhibits cell growth by inducing apoptosis and autophagy via inhibition of m-TOR signaling

(2017) Li-Chun Lin et al.   Journal of Functional Foods

EMT: 2016

(2016) M. Angela Nieto et al.   CELL

Notch and TGFβ form a positive regulatory loop and regulate EMT in epithelial ovarian cancer cells

(2016) Jiesi Zhou et al.   CELLULAR SIGNALLING

Epithelial–mesenchymal transition of ovarian cancer cells is sustained by Rac1 through simultaneous activation of MEK1/2 and Src signaling pathways

(2016) D Fang et al.   ONCOGENE

Triple negative breast cancer development can be selectively suppressed by sustaining an elevated level of cellular cyclic AMP through simultaneously blocking its efflux and decomposition

(2016) Wei Wang et al.   Oncotarget

The Flavonoid Isoliquiritigenin Reduces Lung Inflammation and Mouse Morbidity during Influenza Virus Infection

(2015) Hussein Traboulsi et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Primary debulking surgery and neoadjuvant chemotherapy in the treatment of advanced epithelial ovarian carcinoma

(2015) Shelly M. Seward et al.   CANCER AND METASTASIS REVIEWS

Isoliquiritigenin attenuates oxidative hepatic damage induced by carbon tetrachloride with or without buthionine sulfoximine

(2015) ZhengLin Zhao et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Isoliquiritigenin as a cause of DNA damage and inhibitor of ataxia-telangiectasia mutated expression leading to G2/M phase arrest and apoptosis in oral squamous cell carcinoma

(2015) Shih-Min Hsia et al.   HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK

A Review: The Pharmacology of Isoliquiritigenin

(2015) Fu Peng et al.   PHYTOTHERAPY RESEARCH

Cyclin-dependent kinase 2 is an ideal target for ovary tumors with elevated cyclin E1 expression

(2015) Liu Yang et al.   Oncotarget

Isoliquiritigenin Induces Apoptosis and Inhibits Xenograft Tumor Growth of Human Lung Cancer Cells by Targeting Both Wild Type and L858R/T790M Mutant EGFR

(2014) Sung Keun Jung et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Isoliquiritigenin is a potent inhibitor of NLRP3 inflammasome activation and diet-induced adipose tissue inflammation

(2014) Hiroe Honda et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Ovarian cancer

(2014) Gordon C Jayson et al.   LANCET

Downregulation of COX-2 and CYP 4A signaling by isoliquiritigenin inhibits human breast cancer metastasis through preventing anoikis resistance, migration and invasion

(2014) Hao Zheng et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Inhibitory effects of isoliquiritigenin on the migration and invasion of human breast cancer cells

(2013) Kai-Lee Wang et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Epithelial-mesenchymal plasticity in carcinoma metastasis

(2013) J. H. Tsai et al.   GENES & DEVELOPMENT

Natural Antioxidant-Isoliquiritigenin Ameliorates Contractile Dysfunction of Hypoxic Cardiomyocytes via AMPK Signaling Pathway

(2013) Xiaoyu Zhang et al.   MEDIATORS OF INFLAMMATION

Isoliquiritigenin induces growth inhibition and apoptosis through downregulating arachidonic acid metabolic network and the deactivation of PI3K/Akt in human breast cancer

(2013) Ying Li et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Chemokine C-C motif receptor 5 and C-C motif ligand 5 promote cancer cell migration under hypoxia

(2012) Sensen Lin et al.   CANCER SCIENCE

Vinorelbine inhibits angiogenesis and 95D migration via reducing hypoxic fibroblast stromal cell-derived factor 1 secretion

(2012) Dongdong Fang et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

BlyS is up-regulated by hypoxia and promotes migration of human breast cancer cells

(2012) Jing Zhu et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Glycyrrhizin and isoliquiritigenin suppress the LPS sensor Toll-like receptor 4/MD-2 complex signaling in a different manner

(2012) Hiroe Honda et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Nogo-66 inhibits adhesion and migration of microglia via GTPase Rho pathway in vitro

(2011) Jun Yan et al.   JOURNAL OF NEUROCHEMISTRY

Integrity of SOS1/EPS8/ABI1 Tri-Complex Determines Ovarian Cancer Metastasis

(2010) H. Chen et al.   CANCER RESEARCH

Isoliquiritigenin Suppresses the Toll−Interleukin-1 Receptor Domain-Containing Adapter Inducing Interferon-β (TRIF)-Dependent Signaling Pathway of Toll-Like Receptors by Targeting TBK1

(2010) Se-jeong Park et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Epithelial-Mesenchymal Transitions in Development and Disease

(2009) Jean Paul Thiery et al.   CELL