A Review: The Pharmacology of Isoliquiritigenin

Flavonoids from Astragalus membranaceus and their inhibitory effects on LPS-stimulated pro-inflammatory cytokine production in bone marrow-derived dendritic cells

(2013) Wei Li et al.   ARCHIVES OF PHARMACAL RESEARCH

Preparation of isoliquiritigenin-loaded nanostructured lipid carrier and the in vivo evaluation in tumor-bearing mice

(2013) Xiao Yun Zhang et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Novel plant-derived target drugs: a step forward from licorice?

(2013) Vito Lorusso et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Natural Antioxidant-Isoliquiritigenin Ameliorates Contractile Dysfunction of Hypoxic Cardiomyocytes via AMPK Signaling Pathway

(2013) Xiaoyu Zhang et al.   MEDIATORS OF INFLAMMATION

Isoliquiritigen Enhances the Antitumour Activity and Decreases the Genotoxic Effect of Cyclophosphamide

(2013) Hong Zhao et al.   MOLECULES

Rikkunshito and isoliquiritigenin counteract 5-HT-induced 2C receptor-mediated activation of pro-opiomelanocortin neurons in the hypothalamic arcuate nucleus

(2013) Takeshi Arai et al.   NEUROPEPTIDES

In vivo anti-diabetic activity of derivatives of isoliquiritigenin and liquiritigenin

(2013) Rashmi Gaur et al.   PHYTOMEDICINE

The Inhibitory Effect of Roasted Licorice Extract on Human Metastatic Breast Cancer Cell-Induced Bone Destruction

(2013) Sun Kyoung Lee et al.   PHYTOTHERAPY RESEARCH

Isoliquiritigenin Induces Caspase-Dependent Apoptosis via Downregulation of HPV16 E6 Expression in Cervical Cancer Ca Ski Cells

(2013) Fabienne Hirchaud et al.   PLANTA MEDICA

Dietary Compound Isoliquiritigenin Inhibits Breast Cancer Neoangiogenesis via VEGF/VEGFR-2 Signaling Pathway

(2013) Zhiyu Wang et al.   PLoS One

Involvement of Endoplasmic Reticulum Stress in Isoliquiritigenin-Induced SKOV-3 Cell Apoptosis

(2013) Xuan Yuan et al.   Recent Patents on Anti-Cancer Drug Discovery

Isoliquiritigenin induces growth inhibition and apoptosis through downregulating arachidonic acid metabolic network and the deactivation of PI3K/Akt in human breast cancer

(2013) Ying Li et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Rikkunshito, a Japanese Kampo Medicine, Ameliorates Decreased Feeding Behavior via Ghrelin and Serotonin 2B Receptor Signaling in a Novelty Stress Murine Model

(2013) Chihiro Yamada et al.   Biomed Research International

Inhibitory effects of glycyrrhizae radix and its active component, isoliquiritigenin, on Aβ(25–35)-induced neurotoxicity in cultured rat cortical neurons

(2012) Hong Kyu Lee et al.   ARCHIVES OF PHARMACAL RESEARCH

Isoliquiritigenin isolated from Glycyrrhiza uralensis protects neuronal cells against glutamate-induced mitochondrial dysfunction

(2012) Eun-Ju Yang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Isoliquiritigenin Enhances Radiosensitivity of HepG2 Cells via Disturbance of Redox Status

(2012) Chao Sun et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Isoliquiritigenin treatment induces apoptosis by increasing intracellular ROS levels in HeLa cells

(2012) Xuan Yuan et al.   JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH

Isoliquiritigenin inhibits the growth of multiple myeloma via blocking IL-6 signaling

(2012) Xiangzheng Chen et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

NADPH Oxidase-Derived Reactive Oxygen Species Are Involved in the HL-60 Cell Monocytic Differentiation Induced by Isoliquiritigenin

(2012) Hongmei Chen et al.   MOLECULES

Isoliquiritigenin-Induced Differentiation in Mouse Melanoma B16F0 Cell Line

(2012) Xiaoyu Chen et al.   Oxidative Medicine and Cellular Longevity

Glycyrrhiza uralensisFlavonoids Present in Anti-Asthma Formula, ASHMITM, Inhibit Memory Th2 Responsesin Vitroandin Vivo

(2012) Nan Yang et al.   PHYTOTHERAPY RESEARCH

Analgesic and Uterine Relaxant Effects of Isoliquiritigenin, a Flavone from Glycyrrhiza glabra

(2012) Yulu Shi et al.   PHYTOTHERAPY RESEARCH

Isoliquiritigenin from licorice root suppressed neovascularisation in experimental ocular angiogenesis models

(2011) V. Jhanji et al.   BRITISH JOURNAL OF OPHTHALMOLOGY

Discovering Natural Product Modulators to Overcome Multidrug Resistance in Cancer Chemotherapy

(2011) Chung-Pu Wu et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Comparative Evaluation of Two Structurally Related Flavonoids, Isoliquiritigenin and Liquiritigenin, for Their Oral Infection Therapeutic Potential

(2011) Mark Feldman et al.   JOURNAL OF NATURAL PRODUCTS

Novel Action of the Chalcone Isoliquiritigenin as a Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Inhibitor: Potential Therapy for Cholera and Polycystic Kidney Disease

(2011) Chatchai Muanprasat et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Antibacterial Activity of the Flavonoids from Dalbergia odorifera on Ralstonia solanacearum

(2011) Xiabo Zhao et al.   MOLECULES

Aldose Reductase Inhibitory Compounds from Glycyrrhiza uralensis

(2010) Yeon Sil Lee et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Prenylflavonoids from Glycyrrhiza uralensis and their protein tyrosine phosphatase-1B inhibitory activities

(2010) Songpei Li et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Inhibition of neuraminidase activity by polyphenol compounds isolated from the roots of Glycyrrhiza uralensis

(2010) Young Bae Ryu et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Cancer Chemopreventive Activity and Metabolism of Isoliquiritigenin, a Compound Found in Licorice

(2010) M. Cuendet et al.   Cancer Prevention Research

Inhibition of liver X receptor-α-dependent hepatic steatosis by isoliquiritigenin, a licorice antioxidant flavonoid, as mediated by JNK1 inhibition

(2010) Young Mi Kim et al.   FREE RADICAL BIOLOGY AND MEDICINE

Isoliquiritigenin Suppresses the Toll−Interleukin-1 Receptor Domain-Containing Adapter Inducing Interferon-β (TRIF)-Dependent Signaling Pathway of Toll-Like Receptors by Targeting TBK1

(2010) Se-jeong Park et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Isoliquiritigenin Entails Blockade of TGF-β1-SMAD Signaling for Retarding High Glucose-Induced Mesangial Matrix Accumulation

(2010) Jing Li et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Mammalian Target of Rapamycin Pathway Promotes Tumor-Induced Angiogenesis in Adenoid Cystic Carcinoma: Its Suppression by Isoliquiritigenin through Dual Activation of c-Jun NH2-Terminal Kinase and Inhibition of Extracellular Signal-Regulated Kinase

(2010) Z.-J. Sun et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Suppression of homodimerization of toll-like receptor 4 by isoliquiritigenin

(2010) Se-Jeong Park et al.   PHYTOCHEMISTRY

Isoliquiritigenin induces G2 and M phase arrest by inducing DNA damage and by inhibiting the metaphase/anaphase transition

(2009) Iha Park et al.   CANCER LETTERS

Primary research on chinese medicine treatment of androgen-independent prostate cancer

(2009) Shu-wu Zhang et al.   Chinese Journal of Integrative Medicine

Rikkunshito Ameliorates the Aging-Associated Decrease in Ghrelin Receptor Reactivity via Phosphodiesterase III Inhibition

(2009) Hiroshi Takeda et al.   ENDOCRINOLOGY

Isoliquiritigenin, from Dalbergia odorifera, up-regulates anti-inflammatory heme oxygenase-1 expression in RAW264.7 macrophages

(2009) S. H. Lee et al.   INFLAMMATION RESEARCH

Induction of Cell Cycle Arrest in Prostate Cancer Cells by the Dietary Compound Isoliquiritigenin

(2009) Yeo Myeong Lee et al.   JOURNAL OF MEDICINAL FOOD

Licorice isoliquiritigenin dampens angiogenic activity via inhibition of MAPK-responsive signaling pathways leading to induction of matrix metalloproteinases

(2009) Sang-Wook Kang et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Protective Effects of Isoliquiritigenin Against Methamphetamine-Induced Neurotoxicity in Mice

(2009) Min Jung Lee et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Suppression of the TRIF-dependent signaling pathway of toll-like receptors by isoliquiritigenin in RAW264.7 macrophages

(2009) Se-Jeong Park et al.   MOLECULES AND CELLS

Cytotoxic Activity of Isoliquiritigenin towards CCRF‐CEM Leukemia Cells and its Effect on DNA Damage

(2009) Yuangang Zu et al.   PLANTA MEDICA

The Licorice Flavonoid Isoliquiritigenin Suppresses Phorbol Ester-induced Cyclooxygenase-2 Expression in the Non-tumorigenic MCF-10A Breast Cell Line

(2009) Grace Lau et al.   PLANTA MEDICA

Isoliquiritigenin 2′-methyl ether induces growth inhibition and apoptosis in oral cancer cells via heme oxygenase-1

(2009) Young-Man Lee et al.   TOXICOLOGY IN VITRO

Isoliquiritigenin suppresses cocaine-induced extracellular dopamine release in rat brain through GABAB receptor

(2008) Eun Young Jang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Isoliquiritigenin induces monocytic differentiation of HL-60 cells

(2008) Defang Li et al.   FREE RADICAL BIOLOGY AND MEDICINE

Real-time detection of the early event of cytotoxicity of herbal ingredients on single leukemia cells studied in a microfluidic biochip

(2008) XiuJun Li et al.   Integrative Biology

Isoliquiritigenin inhibits migration and invasion of prostate cancer cells: possible mediation by decreased JNK/AP-1 signaling

(2008) Gyoo Taik Kwon et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Inhibitory Effects of Isoliquiritigenin and Licorice Extract on Voltage-Dependent K+ Currents in H9c2 Cells

(2008) Chisato Noguchi et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Review of Pharmacological Effects ofGlycyrrhiza sp. and its Bioactive Compounds

(2008) Marjan Nassiri Asl et al.   PHYTOTHERAPY RESEARCH

Isoliquiritigenin Inhibits Cell Proliferation by a Heme Oxygenase-Dependent Pathway in Rat Hepatic Stellate Cells

(2008) Sun Woo et al.   PLANTA MEDICA

Induction of Growth Inhibition and Apoptosis in Human Uterine Leiomyoma Cells by Isoliquiritigenin

(2008) Dong-chul Kim et al.   Reproductive Sciences

Combination of isoliquiritigenin and tumor necrosis factor-related apoptosis-inducing ligand induces apoptosis in colon cancer HT29 cells

(2008) Tatsushi Yoshida et al.   Environmental Health and Preventive Medicine