BldD, a master developmental repressor, activates antibiotic production in two Streptomyces species

Transposon-based identification of a negative regulator for the antibiotic hyper-production in Streptomyces

(2018) Shuai Luo et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

SAV4189, a MarR-Family Regulator in Streptomyces avermitilis, Activates Avermectin Biosynthesis

(2018) Jia Guo et al.   Frontiers in Microbiology

wblA , a pleiotropic regulatory gene modulating morphogenesis and daptomycin production in Streptomyces roseosporus

(2017) X. Huang et al.   JOURNAL OF APPLIED MICROBIOLOGY

Activation and mechanism of a cryptic oviedomycin gene cluster via the disruption of a global regulatory gene,adpA, inStreptomyces ansochromogenes

(2017) Jingjing Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Negative regulation of daptomycin production by DepR2, an ArsR-family transcriptional factor

(2017) Xu-Ming Mao et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

DepR1, a TetR Family Transcriptional Regulator, Positively Regulates Daptomycin Production in an Industrial Producer, Streptomyces roseosporus SW0702

(2016) Peng-Hui Yuan et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Intertwining nutrient-sensory networks and the control of antibiotic production inStreptomyces

(2016) Mia Urem et al.   MOLECULAR MICROBIOLOGY

AvaR2, a pseudo γ-butyrolactone receptor homologue fromStreptomyces avermitilis, is a pleiotropic repressor of avermectin and avenolide biosynthesis and cell growth

(2016) Jianya Zhu et al.   MOLECULAR MICROBIOLOGY

SAV742, a Novel AraC-Family Regulator from Streptomyces avermitilis, Controls Avermectin Biosynthesis, Cell Growth and Development

(2016) Di Sun et al.   Scientific Reports

A MarR Family Transcriptional Regulator, DptR3, Activates Daptomycin Biosynthesis and Morphological Differentiation in Streptomyces roseosporus

(2015) Qinling Zhang et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

An efficient blue-white screening based gene inactivation system for Streptomyces

(2015) Pengwei Li et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Transcriptional Regulation of the Daptomycin Gene Cluster inStreptomyces roseosporusby an Autoregulator, AtrA

(2015) Xu-Ming Mao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Overexpression of afsR and Optimization of Metal Chloride to Improve Lomofungin Production in Streptomyces lomondensis S015

(2015) Wei Wang et al.   JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY

c-di-GMP signalling and the regulation of developmental transitions in streptomycetes

(2015) Matthew J. Bush et al.   NATURE REVIEWS MICROBIOLOGY

Tetrameric c-di-GMP Mediates Effective Transcription Factor Dimerization to Control Streptomyces Development

(2014) Natalia Tschowri et al.   CELL

DptR2, a DeoR-type auto-regulator, is required for daptomycin production in Streptomyces roseosporus

(2014) Feng Wang et al.   GENE

Angucyclines as signals modulate the behaviors of Streptomyces coelicolor

(2014) W. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular Regulation of Antibiotic Biosynthesis in Streptomyces

(2013) G. Liu et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Overlapping binding of PhoP and AfsR to the promoter region of glnR in Streptomyces coelicolor

(2012) Fernando Santos-Beneit et al.   MICROBIOLOGICAL RESEARCH

β-Glucuronidase as a Sensitive and Versatile Reporter in Actinomycetes

(2011) Maksym Myronovskyi et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Inactivation of the extracytoplasmic function sigma factor Sig6 stimulates avermectin production in Streptomyces avermitilis

(2011) Libin Jiang et al.   BIOTECHNOLOGY LETTERS

Genome-wide analysis of the role of GlnR in Streptomyces venezuelae provides new insights into global nitrogen regulation in actinomycetes

(2011) Steven T Pullan et al.   BMC GENOMICS

The Level of AdpA Directly Affects Expression of Developmental Genes in Streptomyces coelicolor

(2011) Marcin Wolański et al.   JOURNAL OF BACTERIOLOGY

Regulation mechanisms underlying the biosynthesis of daptomycin and related lipopeptides

(2011) Guojian liao et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

The regulation of the secondary metabolism of Streptomyces: new links and experimental advances

(2011) Gilles P. van Wezel et al.   NATURAL PRODUCT REPORTS

Daptomycin, a Bacterial Lipopeptide Synthesized by a Nonribosomal Machinery

(2010) Lars Robbel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Overexpression of ribosome recycling factor causes increased production of avermectin in Streptomyces avermitilis strains

(2010) Lili Li et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Genes essential for morphological development and antibiotic production in Streptomyces coelicolor are targets of BldD during vegetative growth

(2010) Chris D. Den Hengst et al.   MOLECULAR MICROBIOLOGY

Characterization of a regulatory gene, aveR, for the biosynthesis of avermectin in Streptomyces avermitilis

(2009) Shigeru Kitani et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Daptomycin: mechanisms of action and resistance, and biosynthetic engineering

(2009) Richard H Baltz   CURRENT OPINION IN CHEMICAL BIOLOGY

Identification and Functional Characterization of an afsR Homolog Regulatory Gene from Streptomyces venezuelae ATCC 15439

(2009) Jae Kyung Sohng   JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY

The pathway-specific regulator AveR from Streptomyces avermitilis positively regulates avermectin production while it negatively affects oligomycin biosynthesis

(2009) Jia Guo et al.   MOLECULAR GENETICS AND GENOMICS

The pleiotropic regulator AdpA-L directly controls the pathway-specific activator of nikkomycin biosynthesis inStreptomyces ansochromogenes

(2009) Yuanyuan Pan et al.   MOLECULAR MICROBIOLOGY

Cross-talk between two global regulators in Streptomyces: PhoP and AfsR interact in the control of afsS, pstS and phoRP transcription

(2009) Fernando Santos-Beneit et al.   MOLECULAR MICROBIOLOGY

Role of DptE and DptF in the lipidation reaction of daptomycin

(2008) Melanie Wittmann et al.   FEBS Journal

Streptomyces morphogenetics: dissecting differentiation in a filamentous bacterium

(2008) Klas Flärdh et al.   NATURE REVIEWS MICROBIOLOGY

A key developmental regulator controls the synthesis of the antibiotic erythromycin in Saccharopolyspora erythraea

(2008) C. Chng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA