Effect of cholestasis and NeuroAid treatment on the expression of Bax, Bcl-2, Pgc-1α and Tfam genes involved in apoptosis and mitochondrial biogenesis in the striatum of male rats

MLC901 during sleep deprivation rescues fear memory disruption in rats

(2019) Mohammad Nasehi et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

PGC-1α/SNAI1 axis regulates tumor growth and metastasis by targeting miR-128b in gastric cancer

(2019) Ping Wang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Relations of neuropeptide Y and heme oxygenase-1 expressions with fetal brain injury in rats with intrahepatic cholestasis of pregnancy

(2019) Hongxia Li et al.   Acta Cirurgica Brasileira

Mechanisms of TFAM-mediated cardiomyocyte protection

(2018) George H. Kunkel et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Effect of Combined Treatment with MLC601 (NeuroAiDTM) and Rehabilitation on Post-Stroke Recovery: The CHIMES and CHIMES-E Studies

(2018) Nijasri C. Suwanwela et al.   CEREBROVASCULAR DISEASES

Primary biliary cholangitis: a comprehensive overview

(2017) Ana Lleo et al.   Hepatology International

The Role of Exercise and TFAM in Preventing Skeletal Muscle Atrophy

(2017) Nicholas T. Theilen et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Enterovirus 71 induces apoptosis by directly modulating the conformational activation of pro-apoptotic protein Bax

(2017) Xiaodong Han et al.   JOURNAL OF GENERAL VIROLOGY

Therapeutic effect of Chinese herbal medicines for post stroke recovery

(2017) Shi-You Han et al.   MEDICINE

Training-induced elevations in extracellular lactate in hippocampus and striatum: Dissociations by cognitive strategy and type of reward

(2017) Lori A. Newman et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Magnetic resonance imaging and tensor-based morphometry in the MPTP non-human primate model of Parkinson’s disease

(2017) Michel Modo et al.   PLoS One

ΔNp63 Inhibits Oxidative Stress-Induced Cell Death, Including Ferroptosis, and Cooperates with the BCL-2 Family to Promote Clonogenic Survival

(2017) Gary X. Wang et al.   Cell Reports

Apoptosis as anticancer mechanism: function and dysfunction of its modulators and targeted therapeutic strategies

(2016) Giuseppa Pistritto et al.   Aging-US

Enterovirus 71 2B Induces Cell Apoptosis by Directly Inducing the Conformational Activation of the Proapoptotic Protein Bax

(2016) Haolong Cong et al.   JOURNAL OF VIROLOGY

Mutations in TFAM, encoding mitochondrial transcription factor A, cause neonatal liver failure associated with mtDNA depletion

(2016) Ashlee R. Stiles et al.   MOLECULAR GENETICS AND METABOLISM

The Interaction of Mitochondrial Biogenesis and Fission/Fusion Mediated by PGC-1α Regulates Rotenone-Induced Dopaminergic Neurotoxicity

(2016) Kaige Peng et al.   MOLECULAR NEUROBIOLOGY

Molecular mechanisms of hepatic apoptosis regulated by nuclear factors

(2015) Kewei Wang   CELLULAR SIGNALLING

Bone marrow mononuclear cell transplantation improves mitochondrial bioenergetics in the liver of cholestatic rats

(2015) Daniela Caldas de Andrade et al.   EXPERIMENTAL CELL RESEARCH

Fibrates and cholestasis

(2015) Nisanne S. Ghonem et al.   HEPATOLOGY

The ins and outs of the striatum: Role in drug addiction

(2015) L.M. Yager et al.   NEUROSCIENCE

Antiapoptotic Bcl-2 protein as a potential target for cancer therapy: A mini review

(2015) Hitesh Jagani et al.   Artificial Cells Nanomedicine and Biotechnology

Bile Duct Ligation in Mice: Induction of Inflammatory Liver Injury and Fibrosis by Obstructive Cholestasis

(2015) Carmen G. Tag et al.   Jove-Journal of Visualized Experiments

Expression of pro-apoptotic Bax and anti-apoptotic Bcl-2 proteins in human retinoblastoma

(2014) Lata Singh et al.   CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

Increased Circulatory Asymmetric Dimethylarginine and Multiple Organ Failure: Bile Duct Ligation in Rat as a Model

(2014) Jiunn-Ming Sheen et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Therapeutic Efficacy of Neuro AiD™ (MLC 601), a Traditional Chinese Medicine, in Experimental Traumatic Brain Injury

(2014) Ming-Che Tsai et al.   Journal of Neuroimmune Pharmacology

Nitric oxide mediates the beneficial effect of chronic naltrexone on cholestasis-induced memory impairment in male rats

(2013) Mehrak Javadi-Paydar et al.   BEHAVIOURAL PHARMACOLOGY

Death upon a Kiss: Mitochondrial Outer Membrane Composition and Organelle Communication Govern Sensitivity to BAK/BAX-Dependent Apoptosis

(2013) Thibaud T. Renault et al.   CHEMISTRY & BIOLOGY

Effects of dopamine receptor agonist and antagonists on cholestasis-induced anxiolytic-like behaviors in rats

(2013) Mohammad Reza Zarrindast et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Cholestasis Is Associated with Hepatic Microvascular Dysfunction and Aberrant Energy Metabolism Before and During Ischemia-Reperfusion

(2012) Jaap J. Kloek et al.   ANTIOXIDANTS & REDOX SIGNALING

Mitochondrial transcription factor A regulates mitochondrial transcription initiation, DNA packaging, and genome copy number

(2012) Christopher T. Campbell et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Liver-specific p38α deficiency causes reduced cell growth and cytokinesis failure during chronic biliary cirrhosis in mice

(2012) Ana M. Tormos et al.   HEPATOLOGY

Melatonin attenuates oxidative stress, liver damage and hepatocyte apoptosis after bile-duct ligation in rats

(2012) Cevat Aktas et al.   TOXICOLOGY AND INDUSTRIAL HEALTH

Mitochondrial biogenesis fails in secondary biliary cirrhosis in rats leading to mitochondrial DNA depletion and deletions

(2011) Alessandro Arduini et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

A mitochondrial etiology of Alzheimer and Parkinson disease

(2011) Pinar Coskun et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Opposite effects of statins on mitochondria of cardiac and skeletal muscles: a ‘mitohormesis’ mechanism involving reactive oxygen species and PGC-1

(2011) Jamal Bouitbir et al.   EUROPEAN HEART JOURNAL

Impaired nigrostriatal function precedes behavioral deficits in a genetic mitochondrial model of Parkinson's disease

(2011) Cameron H. Good et al.   FASEB JOURNAL

Hepatoprotective Action of Radix Paeoniae Rubra Aqueous Extract against CCl4-Induced Hepatic Damage

(2011) Ruidong Li et al.   MOLECULES

MLC901, a Traditional Chinese Medicine protects the brain against global ischemia

(2011) H. Quintard et al.   NEUROPHARMACOLOGY

Dexamethasone decreases cholestatic liver injury via inhibition of intrinsic pathway with simultaneous enhancement of mitochondrial biogenesis

(2011) Mao-Meng Tiao et al.   STEROIDS

Over-expression of Tfam improves the mitochondrial disease phenotypes in a mouse model system

(2010) Satoshi Nishiyama et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Elevated Cytosolic Na + Increases Mitochondrial Formation of Reactive Oxygen Species in Failing Cardiac Myocytes

(2010) Michael Kohlhaas et al.   CIRCULATION

Mitochondrial DNA depletion syndromes – Many genes, common mechanisms

(2010) Anu Suomalainen et al.   NEUROMUSCULAR DISORDERS

Neuroprotective and neuroproliferative activities of NeuroAid (MLC601, MLC901), a Chinese medicine, in vitro and in vivo

(2010) C. Heurteaux et al.   NEUROPHARMACOLOGY

Early transcriptional deregulation of hepatic mitochondrial biogenesis and its consequent effects on murine cholestatic liver injury

(2009) Mao-Meng Tiao et al.   APOPTOSIS

Life and death by death receptors

(2009) Maria Eugenia Guicciardi et al.   FASEB JOURNAL

The interaction between high ammonia diet and bile duct ligation in developing rats: assessment by spatial memory and asymmetric dimethylarginine

(2009) Li-Tung Huang et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

Cannabidiol ameliorates cognitive and motor impairments in mice with bile duct ligation

(2009) Iddo Magen et al.   JOURNAL OF HEPATOLOGY

Domestication of the cardiac mitochondrion for energy conversion

(2009) Robert S. Balaban   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Morphological changes of rat astrocytes induced by liver damage but not by manganese chloride exposure

(2009) Susana Rivera-Mancía et al.   METABOLIC BRAIN DISEASE

The role of cellular oxidative stress in regulating glycolysis energy metabolism in hepatoma cells

(2009) Dong-yun Shi et al.   Molecular Cancer

Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment

(2009) Zachary T. Schafer et al.   NATURE

BH3-only proteins in apoptosis and beyond: an overview

(2009) E Lomonosova et al.   ONCOGENE

BH3-only proteins and their roles in programmed cell death

(2009) M Giam et al.   ONCOGENE

Melatonin Ameliorates Bile Duct Ligation-Induced Systemic Oxidative Stress and Spatial Memory Deficits in Developing Rats

(2009) Li-Tung Huang et al.   PEDIATRIC RESEARCH

Superoxide radical formation in diverse organs of rats with experimentally induced obstructive jaundice

(2008) Stelios F. Assimakopoulos et al.   REDOX REPORT