RIG-I-based immunotherapy enhances survival in preclinical AML models and sensitizes AML cells to checkpoint blockade
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Title
RIG-I-based immunotherapy enhances survival in preclinical AML models and sensitizes AML cells to checkpoint blockade
Authors
Keywords
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Journal
LEUKEMIA
Volume -, Issue -, Pages -
Publisher
Springer Science and Business Media LLC
Online
2019-11-19
DOI
10.1038/s41375-019-0639-x
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Note: Only part of the references are listed.- Sensitization to immune checkpoint blockade through activation of a STAT1/NK axis in the tumor microenvironment
- (2019) Rachael M. Zemek et al. Science Translational Medicine
- RIG-I and Other RNA Sensors in Antiviral Immunity
- (2018) Kwan T. Chow et al. Annual Review of Immunology
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- (2018) David L Elion et al. CANCER RESEARCH
- Recent developments in immunotherapy of acute myeloid leukemia
- (2017) Felix S. Lichtenegger et al. Journal of Hematology & Oncology
- Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer
- (2017) Ugur Sahin et al. NATURE
- Interferon Receptor Signaling Pathways Regulating PD-L1 and PD-L2 Expression
- (2017) Angel Garcia-Diaz et al. Cell Reports
- Cutting Edge: The RIG-I Ligand 3pRNA Potently Improves CTL Cross-Priming and Facilitates Antiviral Vaccination
- (2016) Katharina Hochheiser et al. JOURNAL OF IMMUNOLOGY
- STING Pathway Activation Stimulates Potent Immunity against Acute Myeloid Leukemia
- (2016) Emily Curran et al. Cell Reports
- A Detailed Protocol for Characterizing the Murine C1498 Cell Line and its Associated Leukemia Mouse Model
- (2016) Alexia Mopin et al. Jove-Journal of Visualized Experiments
- Immunovirotherapy with vesicular stomatitis virus and PD-L1 blockade enhances therapeutic outcome in murine acute myeloid leukemia
- (2015) W. Shen et al. BLOOD
- Nivolumab in Previously Untreated Melanoma without BRAF Mutation
- (2015) Caroline Robert et al. NEW ENGLAND JOURNAL OF MEDICINE
- Biology and Clinical Relevance of Acute Myeloid Leukemia Stem Cells
- (2015) Andreas Reinisch et al. SEMINARS IN HEMATOLOGY
- An Advanced Preclinical Mouse Model for Acute Myeloid Leukemia Using Patients' Cells of Various Genetic Subgroups and In Vivo Bioluminescence Imaging
- (2015) Binje Vick et al. PLoS One
- RIG-I-like helicases induce immunogenic cell death of pancreatic cancer cells and sensitize tumors toward killing by CD8+ T cells
- (2014) P Duewell et al. CELL DEATH AND DIFFERENTIATION
- RIG-I Modulates Src-Mediated AKT Activation to Restrain Leukemic Stemness
- (2014) Xian-Yang Li et al. MOLECULAR CELL
- Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens
- (2014) Matthew M. Gubin et al. NATURE
- PD-1 blockade induces responses by inhibiting adaptive immune resistance
- (2014) Paul C. Tumeh et al. NATURE
- Immune Cell-Poor Melanomas Benefit from PD-1 Blockade after Targeted Type I IFN Activation
- (2014) T. Bald et al. Cancer Discovery
- Therapeutic Efficacy of Bifunctional siRNA Combining TGF- 1 Silencing with RIG-I Activation in Pancreatic Cancer
- (2013) J. Ellermeier et al. CANCER RESEARCH
- Systemic Cancer Therapy with a Small Molecule Agonist of Toll-like Receptor 7 Can Be Improved by Circumventing TLR Tolerance
- (2011) C. Bourquin et al. CANCER RESEARCH
- Targeted Activation of RNA Helicase Retinoic Acid-Inducible Gene-I Induces Proimmunogenic Apoptosis of Human Ovarian Cancer Cells
- (2010) K. Kubler et al. CANCER RESEARCH
- PD-1/PD-L1 interactions inhibit antitumor immune responses in a murine acute myeloid leukemia model
- (2009) L. Zhang et al. BLOOD
- Targeted Activation of Innate Immunity for Therapeutic Induction of Autophagy and Apoptosis in Melanoma Cells
- (2009) Damià Tormo et al. CANCER CELL
- Recognition of 5′ Triphosphate by RIG-I Helicase Requires Short Blunt Double-Stranded RNA as Contained in Panhandle of Negative-Strand Virus
- (2009) Martin Schlee et al. IMMUNITY
- 5'-triphosphate RNA requires base-paired structures to activate antiviral signaling via RIG-I
- (2009) A. Schmidt et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- 5′-triphosphate-siRNA: turning gene silencing and Rig-I activation against melanoma
- (2008) Hendrik Poeck et al. NATURE MEDICINE
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