CXCL12 promotes atherosclerosis by downregulating ABCA1 expression via the CXCR4/GSK3β/β-cateninT120/TCF21 pathway

Pathways of smooth muscle foam cell formation in atherosclerosis

(2019) Collin S. Pryma et al.   CURRENT OPINION IN LIPIDOLOGY

c-Abl regulates YAPY357 phosphorylation to activate endothelial atherogenic responses to disturbed flow

(2019) Bochuan Li et al.   JOURNAL OF CLINICAL INVESTIGATION

CXCL12 Derived From Endothelial Cells Promotes Atherosclerosis to Drive Coronary Artery Disease

(2019) Yvonne Döring et al.   CIRCULATION

Lansoprazole alleviates pressure overload-induced cardiac hypertrophy and heart failure in mice by blocking the activation of β-catenin

(2019) Hairuo Lin et al.   CARDIOVASCULAR RESEARCH

FCPR03, a novel phosphodiesterase 4 inhibitor, alleviates cerebral ischemia/reperfusion injury through activation of the AKT/GSK3β/ β-catenin signaling pathway

(2019) Bingtian Xu et al.   BIOCHEMICAL PHARMACOLOGY

CXC chemokine ligand 12 (CXCL12) in atherosclerosis: An underlying therapeutic target

(2019) Jia-Hui Gao et al.   CLINICA CHIMICA ACTA

LncRNA ENST00000602558.1 regulates ABCG1 expression and cholesterol efflux from vascular smooth muscle cells through a p65-dependent pathway

(2019) Can Cai et al.   ATHEROSCLEROSIS

Hepatic Forkhead Box Protein A3 Regulates ApoA-I (Apolipoprotein A-I) Expression, Cholesterol Efflux, and Atherogenesis

(2019) Yuanyuan Li et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Associations of ABCG1-mediated cholesterol efflux capacity with coronary artery lipid content assessed by near-infrared spectroscopy

(2019) Kohei Takata et al.   Cardiovascular Diagnosis and Therapy

Cortistatin inhibits arterial calcification in rats via GSK3β/β-catenin and protein kinase C signalling but not c-Jun N-terminal kinase signalling

(2018) Y. Liu et al.   Acta Physiologica

AIBP reduces atherosclerosis by promoting reverse cholesterol transport and ameliorating inflammation in apoE −/− mice

(2018) Min Zhang et al.   ATHEROSCLEROSIS

C1q tumor necrosis factor-related protein 9 in atherosclerosis: Mechanistic insights and therapeutic potential

(2018) Xiao-Hua Yu et al.   ATHEROSCLEROSIS

Visceral adipose tissue-derived serine protease inhibitor accelerates cholesterol efflux by up-regulating ABCA1 expression via the NF-κB/miR-33a pathway in THP-1 macropahge-derived foam cells

(2018) Jia-Hui Gao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

LncRNA MALAT1 regulates oxLDL-induced CD36 expression via activating β-catenin

(2018) Ning Huangfu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Heat shock protein 70 accelerates atherosclerosis by downregulating the expression of ABCA1 and ABCG1 through the JNK/Elk-1 pathway

(2018) Zhen-Wang Zhao et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Apolipoprotein A-1 Binding Protein Inhibits Inflammatory Signaling Pathways by Binding to Apolipoprotein A-1 in THP-1 Macrophages

(2018) Min Zhang et al.   CIRCULATION JOURNAL

Expression and Cellular Localization of CXCR4 and CXCL12 in Human Carotid Atherosclerotic Plaques

(2018) Sophie Merckelbach et al.   THROMBOSIS AND HAEMOSTASIS

Reverse Cholesterol Transport: Molecular Mechanisms and the Non-medical Approach to Enhance HDL Cholesterol

(2018) Leandro R. Marques et al.   Frontiers in Physiology

N-terminal mutation of apoA-I and interaction with ABCA1 reveal mechanisms of nascent HDL biogenesis

(2018) Minjing Liu et al.   JOURNAL OF LIPID RESEARCH

Cholesterol transport system: An integrated cholesterol transport model involved in atherosclerosis

(2018) Xiao-Hua Yu et al.   PROGRESS IN LIPID RESEARCH

Coronary artery disease genes SMAD3 and TCF21 promote opposing interactive genetic programs that regulate smooth muscle cell differentiation and disease risk

(2018) Dharini Iyer et al.   PLoS Genetics

Serum CXCL10 and CXCL12 chemokine levels are associated with the severity of coronary artery disease and coronary artery occlusion

(2017) Vahid Tavakolian Ferdousie et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Clinical Molecular Imaging of Chemokine Receptor CXCR4 Expression in Atherosclerotic Plaque Using68Ga-Pentixafor PET: Correlation with Cardiovascular Risk Factors and Calcified Plaque Burden

(2017) Desiree Weiberg et al.   JOURNAL OF NUCLEAR MEDICINE

Apolipoprotein A-1 binding protein promotes macrophage cholesterol efflux by facilitating apolipoprotein A-1 binding to ABCA1 and preventing ABCA1 degradation

(2016) Min Zhang et al.   ATHEROSCLEROSIS

MiRNA-Related Polymorphisms in miR-146a andTCF21Are Associated with Increased Susceptibility to Coronary Artery Disease in an Iranian Population

(2016) Milad Bastami et al.   Genetic Testing and Molecular Biomarkers

Plasma stromal cell-derived factor 1α/CXCL12 level predicts long-term adverse cardiovascular outcomes in patients with coronary artery disease

(2015) Nima Ghasemzadeh et al.   ATHEROSCLEROSIS

LRP5 deficiency down-regulates Wnt signalling and promotes aortic lipid infiltration in hypercholesterolaemic mice

(2015) Maria Borrell-Pagès et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Platelet-derived CXCL12 regulates monocyte function, survival, differentiation into macrophages and foam cells through differential involvement of CXCR4–CXCR7

(2015) M Chatterjee et al.   Cell Death & Disease

Protein kinase R-like endoplasmic reticulum kinase and glycogen synthase kinase-3α/β regulate foam cell formation

(2014) Cameron S. McAlpine et al.   JOURNAL OF LIPID RESEARCH

Coronary Heart Disease-Associated Variation in TCF21 Disrupts a miR-224 Binding Site and miRNA-Mediated Regulation

(2014) Clint L. Miller et al.   PLoS Genetics

The hydrogen sulfide donor, GYY4137, exhibits anti-atherosclerotic activity in high fat fed apolipoprotein E−/−mice

(2013) Zhen Liu et al.   BRITISH JOURNAL OF PHARMACOLOGY

Higher plasma CXCL12 levels predict incident myocardial infarction and death in chronic kidney disease: findings from the Chronic Renal Insufficiency Cohort study

(2013) N. N. Mehta et al.   EUROPEAN HEART JOURNAL

Disease-Related Growth Factor and Embryonic Signaling Pathways Modulate an Enhancer of TCF21 Expression at the 6q23.2 Coronary Heart Disease Locus

(2013) Clint L. Miller et al.   PLoS Genetics

The many faces and functions of β-catenin

(2012) Tomas Valenta et al.   EMBO JOURNAL

Genome-wide association study in Han Chinese identifies four new susceptibility loci for coronary artery disease

(2012) Xiangfeng Lu et al.   NATURE GENETICS

Beta-Catenin Phosphorylated at Threonine 120 Antagonizes Generation of Active Beta-Catenin by Spatial Localization in trans-Golgi Network

(2012) Cheng Du et al.   PLoS One

The CXCR4 antagonist POL5551 is equally effective as sirolimus in reducing neointima formation without impairing re-endothelialisation

(2012) Karim Hamesch et al.   THROMBOSIS AND HAEMOSTASIS

Endoplasmic Reticulum Stress and Glycogen Synthase Kinase-3β Activation in Apolipoprotein E–Deficient Mouse Models of Accelerated Atherosclerosis

(2011) Cameron S. McAlpine et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The novel atherosclerosis locus at 10q11 regulates plasma CXCL12 levels

(2011) Nehal N. Mehta et al.   EUROPEAN HEART JOURNAL

CXCL12: A New Player in Coronary Disease Identified through Human Genetics

(2011) Samira S. Farouk et al.   TRENDS IN CARDIOVASCULAR MEDICINE

Activation of Vascular Smooth Muscle Parathyroid Hormone Receptor Inhibits Wnt/β-Catenin Signaling and Aortic Fibrosis in Diabetic Arteriosclerosis

(2010) Su-Li Cheng et al.   CIRCULATION RESEARCH

ACSL3 and GSK-3β are essential for lipid upregulation induced by endoplasmic reticulum stress in liver cells

(2010) Yung-Sheng Chang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Atherosclerosis induced by a high-fat diet is alleviated by lithium chloride via reduction of VCAM expression in ApoE-deficient mice

(2010) Sung-E Choi et al.   VASCULAR PHARMACOLOGY