Myo-inositol oxygenase expression profile modulates pathogenic ferroptosis in the renal proximal tubule

Selenium Utilization by GPX4 Is Required to Prevent Hydroperoxide-Induced Ferroptosis

(2018) Irina Ingold et al.   CELL

FGF21 is induced in cisplatin nephrotoxicity to protect against kidney tubular cell injury

(2018) Fanghua Li et al.   FASEB JOURNAL

Glutathione peroxidase 4 overexpression inhibits ROS-induced cell death in diffuse large B-cell lymphoma

(2018) Yuko Kinowaki et al.   LABORATORY INVESTIGATION

Loss of DEPTOR in renal tubules protects against cisplatin-induced acute kidney injury

(2018) Caixia Wang et al.   Cell Death & Disease

Ferroptosis: A Novel Anti-tumor Action for Cisplatin

(2018) Jipeng Guo et al.   Cancer Research and Treatment

Iron accumulation in senescent cells is coupled with impaired ferritinophagy and inhibition of ferroptosis

(2018) Shashank Masaldan et al.   Redox Biology

Oxidative stress induces ferroptotic cell death in retinal pigment epithelial cells

(2018) Kiyohito Totsuka et al.   EXPERIMENTAL EYE RESEARCH

The Development of the Concept of Ferroptosis

(2018) Tal Hirschhorn et al.   FREE RADICAL BIOLOGY AND MEDICINE

Characterization of ferroptosis in murine models of hemochromatosis

(2017) Hao Wang et al.   HEPATOLOGY

MicroRNA-709 Mediates Acute Tubular Injury through Effects on Mitochondrial Function

(2017) Yan Guo et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Management of patients at risk of acute kidney injury

(2017) Jill Vanmassenhove et al.   LANCET

Cell Death Pathways: a Novel Therapeutic Approach for Neuroscientists

(2017) G. Morris et al.   MOLECULAR NEUROBIOLOGY

Ferritinophagy drives uropathogenicEscherichia colipersistence in bladder epithelial cells

(2016) Kyle A. Bauckman et al.   Autophagy

Autophagy promotes ferroptosis by degradation of ferritin

(2016) Wen Hou et al.   Autophagy

Ferroptosis is an autophagic cell death process

(2016) Minghui Gao et al.   CELL RESEARCH

Mechanisms of ferroptosis

(2016) Jennifer Yinuo Cao et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Ferroptosis, a new form of cell death, and its relationships with tumourous diseases

(2016) Haitao Yu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Mechanisms of Selective Autophagy in Normal Physiology and Cancer

(2016) Joseph D. Mancias et al.   JOURNAL OF MOLECULAR BIOLOGY

Ferroptosis, but Not Necroptosis, Is Important in Nephrotoxic Folic Acid–Induced AKI

(2016) Diego Martin-Sanchez et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Beneficial Effects ofMyo-Inositol Oxygenase Deficiency in Cisplatin-Induced AKI

(2016) Rajesh K. Dutta et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

An Overview of Pathways of Regulated Necrosis in Acute Kidney Injury

(2016) Jesper Kers et al.   SEMINARS IN NEPHROLOGY

Transcriptional and Translational Modulation ofmyo-Inositol Oxygenase (Miox) by Fatty Acids

(2015) Tatsuya Tominaga et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Progression after AKI: Understanding Maladaptive Repair Processes to Predict and Identify Therapeutic Treatments

(2015) D. P. Basile et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Glutaminolysis and Transferrin Regulate Ferroptosis

(2015) Minghui Gao et al.   MOLECULAR CELL

Ferritinophagy via NCOA4 is required for erythropoiesis and is regulated by iron dependent HERC2-mediated proteolysis

(2015) Joseph D Mancias et al.   eLife

Ferrostatins Inhibit Oxidative Lipid Damage and Cell Death in Diverse Disease Models

(2014) Rachid Skouta et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Disruption of Renal Tubular Mitochondrial Quality Control by Myo-Inositol Oxygenase in Diabetic Kidney Disease

(2014) M. Zhan et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Regulated Cell Death in AKI

(2014) A. Linkermann et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Quantitative proteomics identifies NCOA4 as the cargo receptor mediating ferritinophagy

(2014) Joseph D. Mancias et al.   NATURE

Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice

(2014) Jose Pedro Friedmann Angeli et al.   NATURE CELL BIOLOGY

Lipid Peroxidation: Production, Metabolism, and Signaling Mechanisms of Malondialdehyde and 4-Hydroxy-2-Nonenal

(2014) Antonio Ayala et al.   Oxidative Medicine and Cellular Longevity

Synchronized renal tubular cell death involves ferroptosis

(2014) Andreas Linkermann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proximal tubule H-ferritin mediates iron trafficking in acute kidney injury

(2013) Abolfazl Zarjou et al.   JOURNAL OF CLINICAL INVESTIGATION

Acute kidney injury: an increasing global concern

(2013) Norbert H Lameire et al.   LANCET

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL

Ongoing Clinical Trials in AKI

(2012) S. Faubel et al.   Clinical Journal of the American Society of Nephrology

The tumor-associated antigen EBAG9 negatively regulates the cytolytic capacity of mouse CD8+ T cells

(2009) Constantin Rüder et al.   JOURNAL OF CLINICAL INVESTIGATION