Elevating SOX2 in prostate tumor cells upregulates expression of neuroendocrine genes, but does not reduce the inhibitory effects of enzalutamide
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Title
Elevating SOX2 in prostate tumor cells upregulates expression of neuroendocrine genes, but does not reduce the inhibitory effects of enzalutamide
Authors
Keywords
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Journal
JOURNAL OF CELLULAR PHYSIOLOGY
Volume -, Issue -, Pages -
Publisher
Wiley
Online
2019-10-06
DOI
10.1002/jcp.29267
References
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Note: Only part of the references are listed.- Sox2 dosage: A critical determinant in the functions of Sox2 in both normal and tumor cells
- (2019) Ethan P. Metz et al. JOURNAL OF CELLULAR PHYSIOLOGY
- SOX2 regulates common and specific stem cell features in the CNS and endoderm derived organs
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- Notch Signaling Controls Transdifferentiation of Pulmonary Neuroendocrine Cells in Response to Lung Injury
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- YAP1 regulates prostate cancer stem cell-like characteristics to promote castration resistant growth
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- Modulation of SOX2 expression delineates an end-point for paclitaxel-effectiveness in breast cancer stem cells
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- Metastatic Latency and Immune Evasion through Autocrine Inhibition of WNT
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- SOX2 functions as a molecular rheostat to control the growth, tumorigenicity and drug responses of pancreatic ductal adenocarcinoma cells
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- NOTCH, ASCL1, p53 and RB alterations define an alternative pathway driving neuroendocrine and small cell lung carcinomas
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- (2015) Lin Zhang et al. MOLECULAR AND CELLULAR BIOLOGY
- Sox2 antagonizes the Hippo pathway to maintain stemness in cancer cells
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- (2014) X Yu et al. PROSTATE CANCER AND PROSTATIC DISEASES
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- Sox2 Is an Androgen Receptor-Repressed Gene That Promotes Castration-Resistant Prostate Cancer
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- The neuropeptide 26RFa is expressed in human prostate cancer and stimulates the neuroendocrine differentiation and the migration of androgeno-independent prostate cancer cells
- (2012) Jessy Alonzeau et al. EUROPEAN JOURNAL OF CANCER
- Elevating SOX2 Levels Deleteriously Affects the Growth of Medulloblastoma and Glioblastoma Cells
- (2012) Jesse L. Cox et al. PLoS One
- Neuroendocrine-derived peptides promote prostate cancer cell survival through activation of IGF-1R signaling
- (2012) John O. DaSilva et al. PROSTATE
- SOX2 promotes tumorigenesis and increases the anti-apoptotic property of human prostate cancer cell
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- Targeting the androgen receptor pathway in prostate cancer
- (2008) Yu Chen et al. CURRENT OPINION IN PHARMACOLOGY
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