Elevating SOX2 in prostate tumor cells upregulates expression of neuroendocrine genes, but does not reduce the inhibitory effects of enzalutamide

Sox2 dosage: A critical determinant in the functions of Sox2 in both normal and tumor cells

(2019) Ethan P. Metz et al.   JOURNAL OF CELLULAR PHYSIOLOGY

SOX2 regulates common and specific stem cell features in the CNS and endoderm derived organs

(2018) Daniel W. Hagey et al.   PLoS Genetics

SOX2 promotes lineage plasticity and antiandrogen resistance in TP53 - and RB1 -deficient prostate cancer

(2017) Ping Mu et al.   SCIENCE

Rb1 and Trp53 cooperate to suppress prostate cancer lineage plasticity, metastasis, and antiandrogen resistance

(2017) Sheng Yu Ku et al.   SCIENCE

Notch Signaling Controls Transdifferentiation of Pulmonary Neuroendocrine Cells in Response to Lung Injury

(2017) Erica Yao et al.   STEM CELLS

YAP1 regulates prostate cancer stem cell-like characteristics to promote castration resistant growth

(2017) Ning Jiang et al.   Oncotarget

Modulation of SOX2 expression delineates an end-point for paclitaxel-effectiveness in breast cancer stem cells

(2017) Pritha Mukherjee et al.   Scientific Reports

Metastatic Latency and Immune Evasion through Autocrine Inhibition of WNT

(2016) Srinivas Malladi et al.   CELL

SOX2 functions as a molecular rheostat to control the growth, tumorigenicity and drug responses of pancreatic ductal adenocarcinoma cells

(2016) Erin L. Wuebben et al.   Oncotarget

Inhibition of Pluripotency Networks by the Rb Tumor Suppressor Restricts Reprogramming and Tumorigenesis

(2015) Michael S. Kareta et al.   Cell Stem Cell

NOTCH, ASCL1, p53 and RB alterations define an alternative pathway driving neuroendocrine and small cell lung carcinomas

(2015) Lydia Meder et al.   INTERNATIONAL JOURNAL OF CANCER

The Hippo Pathway Effector YAP Regulates Motility, Invasion, and Castration-Resistant Growth of Prostate Cancer Cells

(2015) Lin Zhang et al.   MOLECULAR AND CELLULAR BIOLOGY

Sox2 antagonizes the Hippo pathway to maintain stemness in cancer cells

(2015) Upal Basu-Roy et al.   Nature Communications

SNAI2/Slug gene is silenced in prostate cancer and regulates neuroendocrine differentiation, metastasis-suppressor and pluripotency gene expression

(2015) Silvia Esposito et al.   Oncotarget

Quiescent Sox2+ Cells Drive Hierarchical Growth and Relapse in Sonic Hedgehog Subgroup Medulloblastoma

(2014) Robert J. Vanner et al.   CANCER CELL

Sox2 is involved in paclitaxel resistance of the prostate cancer cell line PC-3 via the PI3K/Akt pathway

(2014) DONG LI et al.   Molecular Medicine Reports

SOX2 expression in the developing, adult, as well as, diseased prostate

(2014) X Yu et al.   PROSTATE CANCER AND PROSTATIC DISEASES

Sox2 Acts in a Dose-Dependent Fashion to Regulate Proliferation of Cortical Progenitors

(2014) Daniel W. Hagey et al.   Cell Reports

Sox2 Is an Androgen Receptor-Repressed Gene That Promotes Castration-Resistant Prostate Cancer

(2013) Steven Kregel et al.   PLoS One

The neuropeptide 26RFa is expressed in human prostate cancer and stimulates the neuroendocrine differentiation and the migration of androgeno-independent prostate cancer cells

(2012) Jessy Alonzeau et al.   EUROPEAN JOURNAL OF CANCER

Elevating SOX2 Levels Deleteriously Affects the Growth of Medulloblastoma and Glioblastoma Cells

(2012) Jesse L. Cox et al.   PLoS One

Neuroendocrine-derived peptides promote prostate cancer cell survival through activation of IGF-1R signaling

(2012) John O. DaSilva et al.   PROSTATE

SOX2 promotes tumorigenesis and increases the anti-apoptotic property of human prostate cancer cell

(2011) X. Jia et al.   Journal of Molecular Cell Biology

Partners in crime: deregulation of AR activity and androgen synthesis in prostate cancer

(2010) Karen E. Knudsen et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Targeting the androgen receptor pathway in prostate cancer

(2008) Yu Chen et al.   CURRENT OPINION IN PHARMACOLOGY