Manganese activates autophagy to alleviate endoplasmic reticulum stress–induced apoptosis via PERK pathway

Bafilomycin A1 and U18666A Efficiently Impair ZIKV Infection

(2019) Catarina Sabino et al.   Viruses-Basel

Link of impaired metal ion homeostasis to mitochondrial dysfunction in neurons

(2018) Eunju Nam et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Hairy and enhancer of split 1 (HES1) protects cells from endoplasmic reticulum stress–induced apoptosis through repression ofGADD34

(2018) Ji Eun Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autophagy plays a protective role in Mn-induced toxicity in PC12 cells

(2018) Qian Zhou et al.   TOXICOLOGY

Manganese causes neurotoxic iron accumulation via translational repression of Amyloid Precursor Protein (APP) and H-Ferritin

(2018) Vivek Venkataramani et al.   JOURNAL OF NEUROCHEMISTRY

The Atg2-Atg18 complex tethers pre-autophagosomal membranes to the endoplasmic reticulum for autophagosome formation

(2018) Tetsuya Kotani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Anti-Cancer Natural Products and Their Bioactive Compounds Inducing ER Stress-Mediated Apoptosis: A Review

(2018) Changmin Kim et al.   Nutrients

Sirtuin 3 acts as a negative regulator of autophagy dictating hepatocyte susceptibility to lipotoxicity

(2017) Songtao Li et al.   HEPATOLOGY

Polyphenolic Extract of Euphorbia supina Attenuates Manganese-Induced Neurotoxicity by Enhancing Antioxidant Activity through Regulation of ER Stress and ER Stress-Mediated Apoptosis

(2017) Entaz Bahar et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Trehalose ameliorates oxidative stress-mediated mitochondrial dysfunction and ER stress via selective autophagy stimulation and autophagic flux restoration in osteoarthritis development

(2017) Qian Tang et al.   Cell Death & Disease

HCV-induced autophagosomes are generated via homotypic fusion of phagophores that mediate HCV RNA replication

(2017) Linya Wang et al.   PLoS Pathogens

Bilirubin-induced ER stress contributes to the inflammatory response and apoptosis in neuronal cells

(2016) Mohammed Qaisiya et al.   ARCHIVES OF TOXICOLOGY

Exposure, epidemiology, and mechanism of the environmental toxicant manganese

(2016) Pan Chen et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Tissue kallikrein protects SH-SY5Y neuronal cells against oxygen and glucose deprivation-induced injury through bradykinin B2 receptor-dependent regulation of autophagy induction

(2016) Yanping Liu et al.   JOURNAL OF NEUROCHEMISTRY

The switch from ER stress-induced apoptosis to autophagy via ROS-mediated JNK/p62 signals: A survival mechanism in methotrexate-resistant choriocarcinoma cells

(2015) Yun Shen et al.   EXPERIMENTAL CELL RESEARCH

PERK-mediated Autophagy in Osteosarcoma Cells Resists ER Stress-induced Cell Apoptosis

(2015) Guang-rong Ji et al.   International Journal of Biological Sciences

ER stress and ER stress-mediated apoptosis are involved in manganese-induced neurotoxicity in the rat striatum in vivo

(2015) Ting Wang et al.   NEUROTOXICOLOGY

Protein kinase R-like ER kinase and its role in endoplasmic reticulum stress-decided cell fate

(2015) Z Liu et al.   Cell Death & Disease

Estrogen Receptor Beta-Mediated Proliferative Inhibition and Apoptosis in Human Breast Cancer by Calycosin and Formononetin

(2013) Jian Chen et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Autophagy regulates chlorpyrifos-induced apoptosis in SH-SY5Y cells

(2013) Jae Hyeon Park et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Endoplasmic reticulum stress signaling involvement in manganese-induced nerve cell damage in organotypic brain slice cultures

(2013) Bin Xu et al.   TOXICOLOGY LETTERS

Autophagy as an essential cellular antioxidant pathway in neurodegenerative disease

(2013) Samantha Giordano et al.   Redox Biology

Stress management at the ER: Regulators of ER stress-induced apoptosis

(2012) Adrienne M. Gorman et al.   PHARMACOLOGY & THERAPEUTICS

The pivotal role of c-Jun NH2-terminal kinase-mediated Beclin 1 expression during anticancer agents-induced autophagy in cancer cells

(2008) D-D Li et al.   ONCOGENE