Membrane trafficking as an active regulator of constitutively secreted cytokines

Secretory vesicles of immune cells contain only a limited number of interleukin 6 molecules

(2018) Daniëlle R. J. Verboogen et al.   FEBS LETTERS

The unconventional secretion of IL-1β: Handling a dangerous weapon to optimize inflammatory responses

(2018) Roberto Sitia et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

When trafficking and signaling mix: how subcellular location shapes GPCR activation of heterotrimeric G proteins

(2018) Braden T. Lobingier et al.   TRAFFIC

Valor pronóstico de la interleucina-6 en la mortalidad de los pacientes con sepsis

(2017) Luís Martí Arjona et al.   MEDICINA CLINICA

Ethylene, an early marker of systemic inflammation in humans

(2017) Laurent M. Paardekooper et al.   Scientific Reports

Fluorescence Lifetime Imaging Microscopy reveals rerouting of SNARE trafficking driving dendritic cell activation

(2017) Daniëlle Rianne José Verboogen et al.   eLife

The SNARE VAMP7 Regulates Exocytic Trafficking of Interleukin-12 in Dendritic Cells

(2016) Giulia Chiaruttini et al.   Cell Reports

Sepsis and septic shock

(2016) Richard S. Hotchkiss et al.   Nature Reviews Disease Primers

Effects of endocytosis on receptor-mediated signaling

(2015) Roshanak Irannejad et al.   CURRENT OPINION IN CELL BIOLOGY

A Role for Syntaxin 3 in the Secretion of IL-6 from Dendritic Cells Following Activation of Toll-Like Receptors

(2015) Laura E. Collins et al.   Frontiers in Immunology

Serum Interleukin 6 Before and After Therapy with Tocilizumab Is a Principal Biomarker in Patients with Rheumatoid Arthritis

(2013) K. Shimamoto et al.   JOURNAL OF RHEUMATOLOGY

Cytokines in Sepsis: Potent Immunoregulators and Potential Therapeutic Targets—An Updated View

(2013) Wibke Schulte et al.   MEDIATORS OF INFLAMMATION

IL-1 receptor 2 (IL-1R2) and its role in immune regulation

(2012) Vanessa A. Peters et al.   BRAIN BEHAVIOR AND IMMUNITY

The macrophage response towards LPS and its control through the p38MAPK–STAT3 axis

(2012) Johannes G. Bode et al.   CELLULAR SIGNALLING

Tumor Necrosis Factor-α Signaling in Macrophages

(2012) Narayanan Parameswaran et al.   CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION

Synchronization of secretory protein traffic in populations of cells

(2012) Gaelle Boncompain et al.   NATURE METHODS

Endocytosis and signaling

(2011) Harald W Platta et al.   CURRENT OPINION IN CELL BIOLOGY

Release of TNF-αfrom macrophages is mediated by small GTPase Rab37

(2011) Ryoichi Mori et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

IL-6 promotes acute and chronic inflammatory disease in the absence of SOCS3

(2011) Ben A Croker et al.   IMMUNOLOGY AND CELL BIOLOGY

Interleukin-6 Signaling in Liver-Parenchymal Cells Suppresses Hepatic Inflammation and Improves Systemic Insulin Action

(2010) F. Thomas Wunderlich et al.   Cell Metabolism

Dendritic Cell (DC)-Specific Targeting Reveals Stat3 as a Negative Regulator of DC Function

(2010) Jessica A. Melillo et al.   JOURNAL OF IMMUNOLOGY

Pathways for Cytokine Secretion

(2010) Amanda C. Stanley et al.   PHYSIOLOGY

Endosomes: A legitimate platform for the signaling train

(2009) J. E. Murphy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanisms and pathologic significances in increase in serum interleukin-6 (IL-6) and soluble IL-6 receptor after administration of an anti-IL-6 receptor antibody, tocilizumab, in patients with rheumatoid arthritis and Castleman disease

(2008) N. Nishimoto et al.   BLOOD

A trans-Golgi network golgin is required for the regulated secretion of TNF in activated macrophages in vivo

(2008) Z. Z. Lieu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA