Seipin negatively regulates sphingolipid production at the ER–LD contact site
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Title
Seipin negatively regulates sphingolipid production at the ER–LD contact site
Authors
Keywords
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Journal
JOURNAL OF CELL BIOLOGY
Volume 218, Issue 11, Pages 3663-3680
Publisher
Rockefeller University Press
Online
2019-10-09
DOI
10.1083/jcb.201902072
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Note: Only part of the references are listed.- The ORMDL/Orm–serine palmitoyltransferase (SPT) complex is directly regulated by ceramide: Reconstitution of SPT regulation in isolated membranes
- (2019) Deanna L. Davis et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A Proximity Labeling Strategy Provides Insights into the Composition and Dynamics of Lipid Droplet Proteomes
- (2018) Kirill Bersuker et al. DEVELOPMENTAL CELL
- Sphingolipids activate the endoplasmic reticulum stress surveillance pathway
- (2018) Francisco Piña et al. JOURNAL OF CELL BIOLOGY
- Human SEIPIN Binds Anionic Phospholipids
- (2018) Renhong Yan et al. DEVELOPMENTAL CELL
- Cryo–electron microscopy structure of the lipid droplet–formation protein seipin
- (2018) Xuewu Sui et al. JOURNAL OF CELL BIOLOGY
- The ORMs interact with transmembrane domain 1 of Lcb1 and regulate serine palmitoyltransferase oligomerization, activity and localization
- (2018) Gongshe Han et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Regulation of sphingolipid biosynthesis by the morphogenesis checkpoint kinase Swe1.
- (2017) Neha Chauhan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- De NovoSphingolipid Biosynthesis Is Required for Adipocyte Survival and Metabolic Homeostasis
- (2017) Aikaterini Alexaki et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Quantification of 3-ketodihydrosphingosine using HPLC-ESI-MS/MS to study SPT activity in yeastSaccharomyces cerevisiae
- (2017) Jihui Ren et al. JOURNAL OF LIPID RESEARCH
- Sphingolipids facilitate age asymmetry of membrane proteins in dividing yeast cells
- (2017) Pushpendra Singh et al. MOLECULAR BIOLOGY OF THE CELL
- Sphingolipids and Lipoproteins in Health and Metabolic Disorders
- (2017) Jahangir Iqbal et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Metabolic engineering of Saccharomyces cerevisiae for production of very long chain fatty acid-derived chemicals
- (2017) Tao Yu et al. Nature Communications
- Taming the sphinx: Mechanisms of cellular sphingolipid homeostasis
- (2016) D.K. Olson et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- SEIPIN Regulates Lipid Droplet Expansion and Adipocyte Development by Modulating the Activity of Glycerol-3-phosphate Acyltransferase
- (2016) Martin Pagac et al. Cell Reports
- Seipin is involved in the regulation of phosphatidic acid metabolism at a subdomain of the nuclear envelope in yeast
- (2015) Heimo Wolinski et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Dissecting seipin function: the localized accumulation of phosphatidic acid at ER/LD junctions in the absence of seipin is suppressed by Sei1pΔNterm only in combination with Ldb16p
- (2015) Sungwon Han et al. BMC CELL BIOLOGY
- Targeted Induction of Ceramide Degradation Leads to Improved Systemic Metabolism and Reduced Hepatic Steatosis
- (2015) Jonathan Y. Xia et al. Cell Metabolism
- The seipin complex Fld1/Ldb16 stabilizes ER–lipid droplet contact sites
- (2015) Alexandra Grippa et al. JOURNAL OF CELL BIOLOGY
- Ceramides – Lipotoxic Inducers of Metabolic Disorders
- (2015) Bhagirath Chaurasia et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Metabolism of Very Long-Chain Fatty Acids: Genes and Pathophysiology
- (2014) Takayuki Sassa et al. Biomolecules & Therapeutics
- Adipose-Specific Knockout of Seipin/Bscl2 Results in Progressive Lipodystrophy
- (2014) L. Liu et al. DIABETES
- Control of lipid droplet size in budding yeast requires the collaboration between Fld1 and Ldb16
- (2014) C.-W. Wang et al. JOURNAL OF CELL SCIENCE
- High confidence proteomic analysis of yeast LDs identifies additional droplet proteins and reveals connections to dolichol synthesis and sterol acetylation
- (2014) Erin Currie et al. JOURNAL OF LIPID RESEARCH
- HCV 3a Core Protein Increases Lipid Droplet Cholesteryl Ester Content via a Mechanism Dependent on Sphingolipid Biosynthesis
- (2014) Ursula Loizides-Mangold et al. PLoS One
- Lipids and cell death in yeast
- (2013) Tobias Eisenberg et al. FEMS YEAST RESEARCH
- Therapeutic reversal of chronic alcohol-related steatohepatitis with the ceramide inhibitor myriocin
- (2013) Ming Tong et al. INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY
- Orm Proteins Integrate Multiple Signals to Maintain Sphingolipid Homeostasis
- (2013) Charulatha Gururaj et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- TORC1-regulated protein kinase Npr1 phosphorylates Orm to stimulate complex sphingolipid synthesis
- (2013) Mitsugu Shimobayashi et al. MOLECULAR BIOLOGY OF THE CELL
- A Lipid E-MAP Identifies Ubx2 as a Critical Regulator of Lipid Saturation and Lipid Bilayer Stress
- (2013) Michal A. Surma et al. MOLECULAR CELL
- A novel pathway of ceramide metabolism inSaccharomyces cerevisiae
- (2012) Natalia S. Voynova et al. BIOCHEMICAL JOURNAL
- Very long-chain fatty acids: elongation, physiology and related disorders
- (2012) A. Kihara JOURNAL OF BIOCHEMISTRY
- The ubiquitin-like (UBX)-domain-containing protein Ubx2/Ubxd8 regulates lipid droplet homeostasis
- (2012) Chao-Wen Wang et al. JOURNAL OF CELL SCIENCE
- Regulation of sphingolipid synthesis through Orm1 and Orm2 in yeast
- (2012) M. Liu et al. JOURNAL OF CELL SCIENCE
- Seipin: from human disease to molecular mechanism
- (2012) Bethany R. Cartwright et al. JOURNAL OF LIPID RESEARCH
- Orm protein phosphoregulation mediates transient sphingolipid biosynthesis response to heat stress via the Pkh-Ypk and Cdc55-PP2A pathways
- (2012) Yidi Sun et al. MOLECULAR BIOLOGY OF THE CELL
- Lipid droplets are functionally connected to the endoplasmic reticulum in Saccharomyces cerevisiae
- (2011) N. Jacquier et al. JOURNAL OF CELL SCIENCE
- Molecular characterization of seipin and its mutants: implications for seipin in triacylglycerol synthesis
- (2011) Weihua Fei et al. JOURNAL OF LIPID RESEARCH
- Protein kinase Ypk1 phosphorylates regulatory proteins Orm1 and Orm2 to control sphingolipid homeostasis in Saccharomyces cerevisiae
- (2011) F. M. Roelants et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Tissue-Autonomous Function of Drosophila Seipin in Preventing Ectopic Lipid Droplet Formation
- (2011) Yuan Tian et al. PLoS Genetics
- A Role for Phosphatidic Acid in the Formation of “Supersized” Lipid Droplets
- (2011) Weihua Fei et al. PLoS Genetics
- The Activity of Yeast Hog1 MAPK Is Required during Endoplasmic Reticulum Stress Induced by Tunicamycin Exposure
- (2010) Francisco Torres-Quiroz et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Orm family proteins mediate sphingolipid homeostasis
- (2010) David K. Breslow et al. NATURE
- Orm1 and Orm2 are conserved endoplasmic reticulum membrane proteins regulating lipid homeostasis and protein quality control
- (2010) S. Han et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks
- (2009) Gabriela Bindea et al. BIOINFORMATICS
- Effect of Expression of Genes in the Sphingolipid Synthesis Pathway on the Biosynthesis of Ceramide in Saccharomyces cerevisiae
- (2009) Se Kyung Kim JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY
- Aureobasidin A arrests growth of yeast cells through both ceramide intoxication and deprivation of essential inositolphosphorylceramides
- (2009) Vanessa Cerantola et al. MOLECULAR MICROBIOLOGY
- Universal sample preparation method for proteome analysis
- (2009) Jacek R Wiśniewski et al. NATURE METHODS
- Split mCherry as a new red bimolecular fluorescence complementation system for visualizing protein–protein interactions in living cells
- (2008) Jin-Yu Fan et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Fld1p, a functional homologue of human seipin, regulates the size of lipid droplets in yeast
- (2008) Weihua Fei et al. JOURNAL OF CELL BIOLOGY
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