The apparent deglycase activity of DJ-1 results from the conversion of free methylglyoxal present in fast equilibrium with hemithioacetals and hemiaminals

Reversible histone glycation is associated with disease-related changes in chromatin architecture

(2019) Qingfei Zheng et al.   Nature Communications

The deglycase activity of DJ-1 mitigates α-synuclein glycation and aggregation in dopaminergic cells: Role of oxidative stress mediated downregulation of DJ-1 in Parkinson's disease

(2019) Neelam Sharma et al.   FREE RADICAL BIOLOGY AND MEDICINE

Further characterization of the Maillard deglycase DJ-1 and its prokaryotic homologs, deglycase 1/Hsp31, deglycase 2/YhbO, and deglycase 3/YajL

(2018) Gilbert Richarme et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A transient post-translational modification of active site cysteine alters binding properties of the parkinsonism protein DJ-1

(2018) Arman Mussakhmetov et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Methylglyoxal-derived posttranslational arginine modifications are abundant histone marks

(2018) James J. Galligan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Parkinson’s disease-related DJ-1 functions in thiol quality control against aldehyde attack in vitro

(2017) Noriyuki Matsuda et al.   Scientific Reports

Evidence Against a Role for the Parkinsonism-associated Protein DJ-1 in Methylglyoxal Detoxification

(2016) Daniel H. Pfaff et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bacterial Expression, Purification and In Vitro Phosphorylation of Full-Length Ribosomal S6 Kinase 2 (RSK2)

(2016) Darkhan Utepbergenov et al.   PLoS One

The DJ-1 superfamily member Hsp31 repairs proteins from glycation by methylglyoxal and glyoxal

(2015) Mouadh Mihoub et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Dicarbonyl stress in cell and tissue dysfunction contributing to ageing and disease

(2015) Naila Rabbani et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

N-terminal modifications of cellular proteins: The enzymes involved, their substrate specificities and biological effects

(2015) Sylvia Varland et al.   PROTEOMICS

Stereospecific mechanism of DJ-1 glyoxalases inferred from their hemithioacetal-containing crystal structures

(2014) Dongwook Choi et al.   FEBS Journal

Parkinsonism-associated Protein DJ-1/Park7 Is a Major Protein Deglycase That Repairs Methylglyoxal- and Glyoxal-glycated Cysteine, Arginine, and Lysine Residues

(2014) Gilbert Richarme et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Glutathione-independent Glyoxalase of the DJ-1 Superfamily Plays an Important Role in Managing Metabolically Generated Methylglyoxal inCandida albicans

(2013) Sahar Hasim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A quick, convenient and economical method for the reliable determination of methylglyoxal in millimolar concentrations: the N-acetyl-l-cysteine assay

(2012) Rebekka Wild et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Human DJ-1 and its homologs are novel glyoxalases

(2012) Ju-young Lee et al.   HUMAN MOLECULAR GENETICS

Hsp31 of Escherichia coli K-12 is glyoxalase III

(2011) Krishna P. Subedi et al.   MOLECULAR MICROBIOLOGY

Influence of the microenvironment of thiol groups in low molecular mass thiols and serum albumin on the reaction with methylglyoxal

(2010) Jelena M. Aćimović et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Formation of a Stabilized Cysteine Sulfinic Acid Is Critical for the Mitochondrial Function of the Parkinsonism Protein DJ-1

(2009) Jeff Blackinton et al.   JOURNAL OF BIOLOGICAL CHEMISTRY